(data stored in ACNUC12663 zone)

HOVERGEN: GAGE3_HUMAN

ID   GAGE3_HUMAN             Reviewed;         118 AA.
AC   Q13067;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-NOV-2009, entry version 59.
DE   RecName: Full=G antigen 3;
DE            Short=GAGE-3;
DE   AltName: Full=Cancer/testis antigen 4.3;
DE            Short=CT4.3;
GN   Name=GAGE3;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Melanoma;
RX   MEDLINE=95378788; PubMed=7544395; DOI=10.1084/jem.182.3.689;
RA   van den Eynde B., Peeters O., de Backer O., Gaugler B., Lucas S.,
RA   Boon T.;
RT   "A new family of genes coding for an antigen recognized by autologous
RT   cytolytic T lymphocytes on a human melanoma.";
RL   J. Exp. Med. 182:689-698(1995).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-10, AND MASS
RP   SPECTROMETRY.
RX   MEDLINE=22426906; PubMed=12522270; DOI=10.1073/pnas.2436191100;
RA   Salomon A.R., Ficarro S.B., Brill L.M., Brinker A., Phung Q.T.,
RA   Ericson C., Sauer K., Brock A., Horn D.M., Schultz P.G., Peters E.C.;
RT   "Profiling of tyrosine phosphorylation pathways in human cells using
RT   mass spectrometry.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:443-448(2003).
CC   -!- TISSUE SPECIFICITY: Expressed in a variety of tumor tissues but
CC       not in normal tissues, except testis.
CC   -!- SIMILARITY: Belongs to the GAGE family.
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CC   -!- GENE_FAMILY: HBG056227 [ FAMILY / ALN / TREE ]
DR   EMBL; U19144; AAA82746.1; -; mRNA.
DR   IPI; IPI00011529; -.
DR   STRING; Q13067; -.
DR   PhosphoSite; Q13067; -.
DR   Ensembl; ENST00000355154; ENSP00000347280; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000381700; ENSP00000371119; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000381709; ENSP00000371128; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000399877; ENSP00000382766; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000403519; ENSP00000385596; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000404349; ENSP00000385920; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000404804; ENSP00000384542; ENSG00000215269; Homo sapiens.
DR   Ensembl; ENST00000415752; ENSP00000391465; ENSG00000237671; Homo sapiens.
DR   Ensembl; ENST00000416493; ENSP00000391965; ENSG00000237671; Homo sapiens.
DR   Ensembl; ENST00000420398; ENSP00000397103; ENSG00000237671; Homo sapiens.
DR   Ensembl; ENST00000422672; ENSP00000405110; ENSG00000237671; Homo sapiens.
DR   Ensembl; ENST00000440137; ENSP00000404123; ENSG00000236362; Homo sapiens.
DR   Ensembl; ENST00000445148; ENSP00000416249; ENSG00000215269; Homo sapiens.
DR   Ensembl; ENST00000447358; ENSP00000399049; ENSG00000236362; Homo sapiens.
DR   Ensembl; ENST00000451387; ENSP00000406557; ENSG00000205777; Homo sapiens.
DR   GeneCards; GC0XP049214; -.
DR   GeneCards; GC0XU990066; -.
DR   HGNC; HGNC:4100; GAGE3.
DR   MIM; 300596; gene.
DR   PharmGKB; PA28515; -.
DR   HOGENOM; Q13067; -.
DR   HOVERGEN; Q13067; -.
DR   ArrayExpress; Q13067; -.
DR   Bgee; Q13067; -.
DR   Genevestigator; Q13067; -.
DR   GermOnline; ENSG00000068990; Homo sapiens.
DR   GermOnline; ENSG00000198716; Homo sapiens.
DR   GermOnline; ENSG00000205777; Homo sapiens.
DR   InterPro; IPR008625; GAGE.
DR   Pfam; PF05831; GAGE; 1.
PE   1: Evidence at protein level;
DR   PRODOM; Q13067.
DR   SWISS-2DPAGE; Q13067.
KW   Complete proteome; Phosphoprotein.
FT   DOMAIN        5    115       PRODOM:2005.1:PD012589  18
FT   CHAIN         1    118       G antigen 3.
FT                                /FTId=PRO_0000148341.
FT   MOD_RES      10     10       Phosphotyrosine.
SQ   SEQUENCE   118 AA;  12937 MW;  D97EEBB19E735103 CRC64;
     MNLSRGKSTY YWPRPRRYVQ PPEVIGPMRP EQFSDEVEPA TPEEGEPATQ RQDPAAAQEG
     EDEGASAGQG PKPEADSQEQ GHPQTGCECE DGPDGQEMDP PNPEEVKTPE EGEKQSQC
//

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