(data stored in ACNUC12663 zone)

HOVERGEN: GAGE5_HUMAN

ID   GAGE5_HUMAN             Reviewed;         117 AA.
AC   Q13069; Q6FG72;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   13-OCT-2009, entry version 65.
DE   RecName: Full=G antigen 5;
DE            Short=GAGE-5;
DE   AltName: Full=Cancer/testis antigen 4.5;
DE            Short=CT4.5;
GN   Name=GAGE5;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Melanoma;
RX   MEDLINE=95378788; PubMed=7544395; DOI=10.1084/jem.182.3.689;
RA   van den Eynde B., Peeters O., de Backer O., Gaugler B., Lucas S.,
RA   Boon T.;
RT   "A new family of genes coding for an antigen recognized by autologous
RT   cytolytic T lymphocytes on a human melanoma.";
RL   J. Exp. Med. 182:689-698(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S.,
RA   Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W.,
RA   Korn B., Zuo D., Hu Y., LaBaer J.;
RT   "Cloning of human full open reading frames in Gateway(TM) system entry
RT   vector (pDONR201).";
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Liver;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- TISSUE SPECIFICITY: Expressed in a variety of tumor tissues but
CC       not in normal tissues, except testis.
CC   -!- SIMILARITY: Belongs to the GAGE family.
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CC   -!- GENE_FAMILY: HBG056227 [ FAMILY / ALN / TREE ]
DR   EMBL; U19146; AAA82748.1; -; mRNA.
DR   EMBL; CR542236; CAG47032.1; -; mRNA.
DR   EMBL; BC024914; AAH24914.1; -; mRNA.
DR   IPI; IPI00011531; -.
DR   RefSeq; NP_001465.1; -.
DR   RefSeq; NP_001466.1; -.
DR   UniGene; Hs.460641; -.
DR   UniGene; Hs.632815; -.
DR   IntAct; Q13069; 1.
DR   STRING; Q13069; -.
DR   PhosphoSite; Q13069; -.
DR   Ensembl; ENST00000355154; ENSP00000347280; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000381700; ENSP00000371119; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000381709; ENSP00000371128; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000399877; ENSP00000382766; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000403519; ENSP00000385596; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000404349; ENSP00000385920; ENSG00000205777; Homo sapiens.
DR   Ensembl; ENST00000404804; ENSP00000384542; ENSG00000215269; Homo sapiens.
DR   Ensembl; ENST00000415752; ENSP00000391465; ENSG00000237671; Homo sapiens.
DR   Ensembl; ENST00000416493; ENSP00000391965; ENSG00000237671; Homo sapiens.
DR   Ensembl; ENST00000420398; ENSP00000397103; ENSG00000237671; Homo sapiens.
DR   Ensembl; ENST00000422672; ENSP00000405110; ENSG00000237671; Homo sapiens.
DR   Ensembl; ENST00000440137; ENSP00000404123; ENSG00000236362; Homo sapiens.
DR   Ensembl; ENST00000445148; ENSP00000416249; ENSG00000215269; Homo sapiens.
DR   Ensembl; ENST00000447358; ENSP00000399049; ENSG00000236362; Homo sapiens.
DR   Ensembl; ENST00000451387; ENSP00000406557; ENSG00000205777; Homo sapiens.
DR   GeneID; 2576; -.
DR   GeneID; 2577; -.
DR   KEGG; hsa:2576; -.
DR   KEGG; hsa:2577; -.
DR   CTD; 2577; -.
DR   GeneCards; GC0XP049214; -.
DR   GeneCards; GC0XP049215; -.
DR   HGNC; HGNC:4102; GAGE5.
DR   MIM; 300598; gene.
DR   PharmGKB; PA28517; -.
DR   HOVERGEN; Q13069; -.
DR   NextBio; 10189; -.
DR   ArrayExpress; Q13069; -.
DR   Bgee; Q13069; -.
DR   Genevestigator; Q13069; -.
DR   GermOnline; ENSG00000068990; Homo sapiens.
DR   GermOnline; ENSG00000198716; Homo sapiens.
DR   GermOnline; ENSG00000205777; Homo sapiens.
DR   InterPro; IPR008625; GAGE.
DR   Pfam; PF05831; GAGE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q13069.
DR   SWISS-2DPAGE; Q13069.
KW   Complete proteome.
FT   DOMAIN        1    114       PRODOM:2005.1:PD012589  18
FT   CHAIN         1    117       G antigen 5.
FT                                /FTId=PRO_0000148343.
FT   CONFLICT     23     23       V -> M (in Ref. 2; CAG47032).
SQ   SEQUENCE   117 AA;  12924 MW;  234A865E2ECDDD06 CRC64;
     MSWRGRSTYY WPRPRRYVQP PEVIGPMRPE QFSDEVEPAT PEEGEPATQR QDPAAAQEGE
     DEGASAGQGP KPEADSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE GEKQSQC
//

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