(data stored in SCRATCH3701 zone)

HOGENOM6: GARV3_1_PE131

ID   GARV3_1_PE131                        STANDARD;      PRT;   879 AA.
AC   GARV3_1_PE131; E3D7Q9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA topoisomerase (GARV3_1.PE131) (ATP-hydrolyzing) subunit
DE   A; EC=5.99.1 3; .
GN   Name=gyrA; OrderedLocusNames=HMPREF0421_20131;
OS   GARDNERELLA VAGINALIS ATCC 14019.
OC   Bacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales;
OC   Bifidobacteriaceae; Gardnerella.
OX   NCBI_TaxID=525284;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS GARV3_1.PE131.
CC       Gardnerella vaginalis ATCC 14019 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:E3D7Q9_GARV3
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E3D7Q9; -.
DR   EMBL; CP002104; ADP38217.1; -; Genomic_DNA.
DR   RefSeq; YP_003985240.1; NC_014644.1.
DR   GeneID; 9903667; -.
DR   GenomeReviews; CP002104_GR; HMPREF0421_20131.
DR   KEGG; gvg:HMPREF0421_20131; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; GARV3_1.PE131; -.
DR   PRODOM; GARV3_1_PE131.
DR   SWISS-2DPAGE; GARV3_1_PE131.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   879 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVDEINAAND GEYRDQLPDG SMEPQSPQES DNTDYGLMKG ARVKHMDLQQ EMRESYLAYA
     LSVIVERALP DVRDGLKPVH RRVIYAMYDG GYRPDRGYNK CSRVVGDVMG KYHPHGDSAI
     YDTLVRMAQS WSMRYMLVDG QGNFGSPGDD PAAAMRYTEC RMAPLAMEMV RDIDKDTVDF
     LPNYDGKTQE PTVLPARFPN LLVNGSAGIA VGMATNIPPH NMREVADGVH WALDHPDASN
     SELLEALIQR IKGPDFPTGA TILGHKGIEQ AYRTGRGLIT MRAVVNTEEI KGRMCLVVTE
     LPYQVNPDRL AASIREAVRD GKIQGIADMR DETSGRTGQR LVLVLKRDAV PKVVLNNLYK
     HSQLQQTFGA NMLALVDGVP RTLSLDAFIR HWVSHQLEVI DRRTRYLKRE AEERDHILQG
     YLKALDMIDE VVALIRSSKD VDTARTGLMN LLDVDDVQAD AILAMQLRRL AALERQKILD
     EHEELMRKIE DYNDILASPE RQRKIVGDEL DEIVAKYGDE RRTRILPFSG EMNVEDLIAE
     ENVVVTVTRA GYIKRTKADE YRAQHRGGKG IKGAKLREDD VVDHFFLTST HNWLLFFTNR
     GRVYRIKAYE LPEGSRDSKG QHVANLLQFT PGETIQAVLS IPNYDVAKYL VLATRSGKVK
     KTALQEYDSP RQGGLIAVRL MTNEETGEPA DELIGAALCN SEDDIILVSK LGMSLKFRAD
     DEQLRPMGRQ TAGVQGMRFR EDDELLDMDV VSVETSKDLL VVTNEGFAKR TAIEEYRLQG
     RNGYGVKAVQ LAEGRGSLVG ALIVEETDQV MAIMKSGKVI RSDVNEVKRT GRTTQGVTLA
     KPDKGDEIIS IARNEERDDE SDNKNEEVEE NTSRRNLDE
//

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