(data stored in ACNUC7421 zone)

HOGENOM: GARV4_1_PE1013

ID   GARV4_1_PE1013                       STANDARD;      PRT;   514 AA.
AC   GARV4_1_PE1013; D2RBV0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Inosine-5'-monophosphate dehydrogenase; EC=1.1.1 205;
DE   (GARV4_1.PE1013).
GN   Name=guaB; OrderedLocusNames=HMPREF0424_1082;
OS   GARDNERELLA VAGINALIS 409-05.
OC   Bacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales;
OC   Bifidobacteriaceae; Gardnerella.
OX   NCBI_TaxID=553190;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS GARV4_1.PE1013.
CC       Gardnerella vaginalis 409-05 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:D2RBV0_GARV4
CC   -!- CATALYTIC ACTIVITY: Inosine 5'-phosphate + NAD(+) + H(2)O =
CC       xanthosine 5'-phosphate + NADH.
CC   -!- PATHWAY: Purine metabolism; XMP biosynthesis via de novo pathway;
CC       XMP from IMP: step 1/1.
CC   -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC   -!- GENE_FAMILY: HOG000165755 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D2RBV0; -.
DR   EMBL; CP001849; ADB14276.1; -; Genomic_DNA.
DR   RefSeq; YP_003374285.1; NC_013721.1.
DR   ProteinModelPortal; D2RBV0; -.
DR   GeneID; 8708905; -.
DR   GenomeReviews; CP001849_GR; HMPREF0424_1082.
DR   KEGG; gva:HMPREF0424_1082; -.
DR   OMA; GIGIVHK; -.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR000644; Cysta_beta_synth_core.
DR   InterPro; IPR005990; IMP_DH.
DR   InterPro; IPR018529; IMP_DH-rel.
DR   InterPro; IPR015875; IMP_DH/GMP_Rdtase_CS.
DR   InterPro; IPR001093; IMP_DH_GMPRt.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   PANTHER; PTHR11911:SF6; IMP_DH_GMPRtase; 1.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF00478; IMPDH; 1.
DR   PIRSF; PIRSF000130; IMPDH; 1.
DR   SMART; SM00116; CBS; 2.
DR   TIGRFAMs; TIGR01302; IMP_dehydrog; 1.
DR   PROSITE; PS51371; CBS; 2.
DR   PROSITE; PS00487; IMP_DH_GMP_RED; 1.
DR   HOGENOMDNA; GARV4_1.PE1013; -.
KW   Complete proteome; GMP biosynthesis; Metal-binding; NAD;
KW   Oxidoreductase; Potassium; Purine biosynthesis.
SQ   SEQUENCE   514 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MATTDMNTES VYAPVPPIFE KLGLAYDDVL LLPNETDVIP SEVDTSTRLT REITMKVPTI
     SAAMDTVTES DMAIAMARNG GIGVLHRNLS IDDQAAQVDI VKRSESGMIT DPLTVHPDAT
     LADLDKLCGR FHISGLPVVD SENRLVGIIT NRDMRFIASE DYDRLKVKDV MTRENLVTGP
     SNISKEDAHR LLADNKIEKL PLVDAEGKLT GLITVKDFVK TEQYPDATKD DQGRLRVAAG
     IGFLGDAWQR ACALMEAGVD VLVVDTANGE ARLALDMIRR IKADKAFDGV QIIGGNIATR
     QGAQAMIDAG VDAVKVGVGP GSICTTRVVA GVGVPQLTAV YDAAQACKAA GIPCIADGGI
     HYSGDIAKAL VAGADTVMLG GTLAGCEEAP GEKVLLHGKQ YKLYRGMGSL GAMAPRGKKS
     YSKDRYFQAD VTSSDKVVPE GVEGEVPYRG PLNAVLYQLL GGLHQSMFYV GAHNIKEMQE
     RGRFIRITDA GLRESHPHDI VMTAEAPNYS GFHN
//

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