(data stored in SCRATCH3701 zone)

HOGENOM6: GARV4_1_PE37

ID   GARV4_1_PE37                         STANDARD;      PRT;   876 AA.
AC   GARV4_1_PE37; D2RCN4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (GARV4_1.PE37).
GN   Name=gyrA; OrderedLocusNames=HMPREF0424_0040;
OS   GARDNERELLA VAGINALIS 409-05.
OC   Bacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales;
OC   Bifidobacteriaceae; Gardnerella.
OX   NCBI_TaxID=553190;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS GARV4_1.PE37.
CC       Gardnerella vaginalis 409-05 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:D2RCN4_GARV4
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D2RCN4; -.
DR   EMBL; CP001849; ADB14274.1; -; Genomic_DNA.
DR   RefSeq; YP_003373311.1; NC_013721.1.
DR   GeneID; 8708757; -.
DR   GenomeReviews; CP001849_GR; HMPREF0424_0040.
DR   KEGG; gva:HMPREF0424_0040; -.
DR   OMA; TGRGRIY; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; GARV4_1.PE37; -.
DR   PRODOM; GARV4_1_PE37.
DR   SWISS-2DPAGE; GARV4_1_PE37.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   876 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVDEINSARD DAERDQLPDG SMEPQSPQEA DNTDYGLMKG ARVKNMDLQQ EMRESYLAYA
     LSVIVERALP DVRDGLKPVH RRVIYAMYDG GYRPDRGYNK CSRVVGDVMG KYHPHGDSAI
     YDTLVRMAQS WSMRYMLVDG QGNFGSPGDD PAAAMRYTEC RMAPLAMEMV RDIDKDTVDF
     LPNYDGKTQE PTVLPARFPN LLVNGSAGIA VGMATNIPPH NMREVADGVH WALDHPDASK
     EELLEALIQR IKGPDFPTGA TILGHKGIEQ AYRTGRGLIT MRAVVNTEEI KGRMCLVVTE
     LPYQVNPDRL AASIREAVRD GKIQGIADMR DETSGRTGQR LVLVLKRDAV PKVVLNNLYK
     HSQLQQTFGA NMLALVDGVP RTLSLDAFIR HWVTHQLEVI DRRTRYLKRE AEERDHILQG
     YLKALDMIDE VVALIRSSKD VETARTGLMN LLDVDEVQAD AILAMQLRRL AALERQKILD
     EHEDLMIKIA DYNDILASPE RQRKIVGDEL DEIVAKYGDD RRTKILPFSG EMNVEDLIAE
     ENVVVTVTRA GYIKRTKADE YRAQHRGGKG IKGAKLREDD VVDHFFLTST HNWLLFFTNR
     GRVYRLKAYE LPEGSRDSKG QHVANLLQFT PGETIQAVLS IPNYDVAKYL VLATRSGKVK
     KTALQEYDSP RQGGLIAVRL MANEETGEPV DELIGAALCN SEDDIILVSK LGMSLKFRAD
     DEQLRPMGRQ TAGVQGMRFR EGDELLDMDV VAAETSKDLL VVTNEGFAKR TAIEEYRLQG
     RNGYGVKAVQ LAEGRGSLVG ALIVEETDQV MAIMKSGKVI RSDINEVKRT GRTTQGVTLA
     KPDKGDEIIS IARNEETDDE ENQLEEKEAT SENEEA
//

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