(data stored in SCRATCH3701 zone)

HOGENOM6: HAES1_2_PE1171

ID   HAES1_2_PE1171                       STANDARD;      PRT;   881 AA.
AC   HAES1_2_PE1171; Q0I3Y3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (HAES1_2.PE1171).
GN   Name=gyrA; OrderedLocusNames=HS_1163;
OS   HAEMOPHILUS SOMNUS 129PT.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=205914;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HAES1_2.PE1171.
CC       Haemophilus somnus 129PT, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q0I3Y3_HAES1
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q0I3Y3; -.
DR   EMBL; CP000436; ABI25438.1; -; Genomic_DNA.
DR   RefSeq; YP_719375.1; NC_008309.1.
DR   ProteinModelPortal; Q0I3Y3; -.
DR   SMR; Q0I3Y3; 30-521, 534-868.
DR   STRING; Q0I3Y3; -.
DR   GeneID; 4240664; -.
DR   GenomeReviews; CP000436_GR; HS_1163.
DR   KEGG; hso:HS_1163; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q0I3Y3; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; HAES1_2.PE1171; -.
DR   PRODOM; HAES1_2_PE1171.
DR   SWISS-2DPAGE; HAES1_2_PE1171.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   881 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDFTPNVTP VSIEEELKSS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF SMDQSSNTYN
     KAYVKSARVV GDVIGKYHPH GDSAVYDTIV RMAQPFSLRY MLVDGQGNFG SVDGDAPAAM
     RYTEVRMQKI TQELLTDLDK ETVDFSPNYD GKEMIPDVLP TKIPTLLVNG SSGIAVGMAT
     NIPPHNLNEV LDGCLAYVDN EEISIDELMQ YIPGPDFPTA ALINGRKGIE EAYKTGRGKI
     YVRAKAEIET NDKGRETIVV TEIPYQVNKA KLVEKIAELV REKKIEGISN VRDVSNKEGN
     RVEVEVKRDA VGEVVLNNLY ALTQMQVTFG INMVALDHGQ PKLLNLKQII EAFVRHRREV
     ITRRTVFELR KARERAHILE GLAIALANID PVIELIRASK TADEARVGLL SQAWELGNVA
     TMLSATGVDS SRPDNLADNL GIIDGKYYLS DEQARAILDL RLQRLTGLEH EKIVTEYQEI
     LIEIGKLLHI LNSADRLKEV LCEELEKVKE EFGDARRTEI TSASGDINLE DLITQEDVIV
     TLSHAGYVKY QPLTDYEAQR RGGKGKSATK MKDEDFIERL LVANTHDTIL CFSSRGRLYW
     LKVYQLPQAN RGARGRPIVN ILPLQENERI TAILPVAAYE EDKFIVMATA GGLVKKIALT
     EFSRPRSSGI IALNLRDEDE LIGVDITDGT NEIMLFSSQG RVVRFEENAV RAMGRLATGV
     RGIKLALTND ISDDESAVEI EDISDEDTKE PLDLNVDKVV SLVIPKNDGA ILTATQNGYG
     KRTALSEYPT KSRNTKGVIS IKVSDRNGKV VAATQVEEND QIMLITDAGT LVRTRVSEIS
     IVGRNTQGVR LIRTAETEQV VSLERVCDTD EDEENIDNNF E
//

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