(data stored in ACNUC30630 zone)

HOGENOM: HALVD_4_PE2400

ID   HALVD_4_PE2400                       STANDARD;      PRT;   524 AA.
AC   HALVD_4_PE2400; P33975; D4GT37;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Anthranilate synthase component 1; EC=4.1.3 27;AltName:
DE   Full=Anthranilate synthase component I; (HALVD_4.PE2400).
GN   Name=trpE; OrderedLocusNames=HVO_2454;
OS   HALOFERAX VOLCANII DS2.
OC   Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae;
OC   Haloferax.
OX   NCBI_TaxID=309800;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HALVD_4.PE2400.
CC       Haloferax volcanii DS2 chromosome, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:TRPE_HALVD
CC   -!- CATALYTIC ACTIVITY: Chorismate + L-glutamine = anthranilate +
CC       pyruvate + L-glutamate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 1/5.
CC   -!- SUBUNIT: Tetramer of two components I and two components II (By
CC       similarity).
CC   -!- MISCELLANEOUS: Component I catalyzes the formation of anthranilate
CC       using ammonia rather than glutamine, whereas component II provides
CC       glutamine amidotransferase activity.
CC   -!- SIMILARITY: Belongs to the anthranilate synthase component I
CC       family.
CC   -!- GENE_FAMILY: HOG000025142 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P33975; D4GT37; -.
DR   EMBL; M83788; AAA73177.1; -; Genomic_DNA.
DR   EMBL; CP001956; ADE02423.1; -; Genomic_DNA.
DR   PIR; A42301; A42301.
DR   ProteinModelPortal; P33975; -.
DR   GO; GO:0004049; F:anthranilate synthase activity; IEA:EC.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR019999; Anth_synth_I.
DR   InterPro; IPR006805; Anth_synth_I_N.
DR   InterPro; IPR010116; Anthranilate_synth_I_arc.
DR   InterPro; IPR015890; Chorismate-bd_C.
DR   Gene3D; G3DSA:3.60.120.10; TRPE_1_chor_bd; 1.
DR   Pfam; PF04715; Anth_synt_I_N; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   PRINTS; PR00095; ANTSNTHASEI.
DR   SUPFAM; SSF56322; TRPE_1_chor_bd; 1.
DR   TIGRFAMs; TIGR01820; TrpE-arch; 1.
DR   HOGENOMDNA; HALVD_4.PE2400; -.
KW   anthranilate synthase component I;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; Lyase; Tryptophan biosynthesis.
SQ   SEQUENCE   524 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTAPDTDREE FVSLAGDADG PVVTHLVADL DVSVDPLAAY TTLADRSDYG FLLESAEKVS
     SSNPQGAFSA PATAADSHAR FSFVGYDPEA VVTVGPDGVD VTDLGGPAAE FVGAGDGDVL
     DSLRGALPDL PRVNFPETDR QTLTGGLVGF LAYEAVYDLW LDEVGRERPD TDDPDAEFVL
     TTRTLSFDHR EDAVRLVCTP VVSPDDDPGE VYDGVVAEAE RVAEKLRAAD DPAPGGFERT
     GEDAGSREEY EAAVRKTKEH VRDGDIYQGV ISRTRKLRGQ VDPVGLYASL REVNPSPYMF
     LLRHGDRRVV GASPETLVSV RGDRVVVNPI AGTCQRGSGP VEDRRLAGEL LADAKERAEH
     TMLVDLGRND VRRVSTPGSV RVEDFMSIIK YSHVQHIEST VSGTLDADAD AFDATRATFP
     AGTLTGAPKV RAMEIIDDLE AEPRGVYGGG VGYYSWTGDA DVAIVIRTAT VDSGGADDAI
     TVRAGAGIVA DSDPTAEYEE TEQKMGGVLD AVRRIEYGTE EASQ
//

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