(data stored in SCRATCH3701 zone)

HOGENOM6: HALWD_1_PE1581

ID   HALWD_1_PE1581                       STANDARD;      PRT;   856 AA.
AC   HALWD_1_PE1581; Q18GY3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (HALWD_1.PE1581).
GN   Name=gyrA; OrderedLocusNames=HQ2651A;
OS   HALOQUADRATUM WALSBYI DSM 16790.
OC   Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae;
OC   Haloquadratum.
OX   NCBI_TaxID=362976;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HALWD_1.PE1581.
CC       Haloquadratum walsbyi DSM 16790, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:GYRA_HALWD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q18GY3; -.
DR   EMBL; AM180088; CAJ52762.1; -; Genomic_DNA.
DR   RefSeq; YP_658368.1; NC_008212.1.
DR   ProteinModelPortal; Q18GY3; -.
DR   STRING; Q18GY3; -.
DR   GeneID; 4194090; -.
DR   GenomeReviews; AM180088_GR; HQ2651A.
DR   KEGG; hwa:HQ2651A; -.
DR   NMPDR; fig|362976.6.peg.1655; -.
DR   eggNOG; arNOG05278; -.
DR   OMA; QRENVIV; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; HWAL362976:HQ2651A-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; HALWD_1.PE1581; -.
DR   PRODOM; HALWD_1_PE1581.
DR   SWISS-2DPAGE; HALWD_1_PE1581.
KW   DNA gyrase / DNA topoisomerase II subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   856 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSSDAPERFD PETGIAAEVE TARIEREMEQ SYIDYAMSVI AGRALPDARD GLKPVHRRIL
     YAMHQSGISA RSAHRKSSSI VGETMGDYHP HGDSAIYNAL ARMAQDFSMR NPLVDGQGNF
     GSVDGDPPAA MRYTEARMSP IAEELLDNIE MDTVEFTANY DDRLSEPAVL PAAFPNLLVN
     GSSGIAVGMS TNIPPHNLGE VIDATIHLIH HPECTVEDLM NHVQGPDFPT GANIVGQNAI
     YKAYKTGRGR VRVRAEFDVQ DDRIVITELP FQTNKARLVE RIADNVNAGT IEGIRDLRDE
     SDRDGIRVVV ELKRGANPDI VKNQLLEHHL ESTFGVINLA LVDGQPQVLT LKETLHEYLE
     HRRTVVRRRS QYELDEKRDR AHILEGRLRA LEQVDDVVDI IRNSTDRDNA KAALRGEHVV
     ESDERGESLP TFDFSEDQAN HIVAMQLGSL TSLESDEIED EYESVQERIE RLQTILNNPD
     ELDAVVEDEL ATIRDKYADE RRTRIIEDDG TVTHEDLIAQ EDVVVVVTED DYIKRMSLED
     FRSQHRGGKG IIGTSLKDGD TVSSVYVANT HDYLLYFTSH GQVYQLKTYQ IPEMSRTARG
     KSAVNLLELD DGEQITAVVN TAEMDIDDDE ERYFTMVTQS GYIKRTSVNS FQNIRSTGII
     AISLGADDKL IDVEVTDGNR DIILGTRKGM AIRFNEGDVR SVGRSARGVH GIKLEDTDAV
     AALAAVDDDQ DDWVLTVTEH GYGKRTDIDR YRQQSRNGKG LIDIKTNERN GHVCEVETVG
     ISDELFMMSR KGQILRTPVD DISTVGRNTM GVIVMDLEDT DTVASVDTHP RTDDSSEADS
     GDGESESENA TATTPS
//

If you have problems or comments...

PBIL Back to PBIL home page