(data stored in ACNUC30630 zone)

HOGENOM: HAMAR1_8_PE619

ID   HAMAR1_8_PE619                       STANDARD;      PRT;   489 AA.
AC   HAMAR1_8_PE619; Q5V448;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Anthranilate synthase component 1 1; EC=4.1.3 27;AltName:
DE   Full=Anthranilate synthase component I 1; (HAMAR1_8.PE619).
GN   Name=trpE1; OrderedLocusNames=rrnAC0709;
OS   HALOARCULA MARISMORTUI ATCC 43049.
OC   Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae;
OC   Haloarcula.
OX   NCBI_TaxID=272569;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HAMAR1_8.PE619.
CC       Haloarcula marismortui ATCC 43049 chromosome chromosome I, complete
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:TRPE1_HALMA
CC   -!- CATALYTIC ACTIVITY: Chorismate + L-glutamine = anthranilate +
CC       pyruvate + L-glutamate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 1/5.
CC   -!- SUBUNIT: Tetramer of two components I and two components II (By
CC       similarity).
CC   -!- MISCELLANEOUS: Component I catalyzes the formation of anthranilate
CC       using ammonia rather than glutamine, whereas component II provides
CC       glutamine amidotransferase activity.
CC   -!- SIMILARITY: Belongs to the anthranilate synthase component I
CC       family.
CC   -!- GENE_FAMILY: HOG000025142 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5V448; -.
DR   EMBL; AY596297; AAV45704.1; -; Genomic_DNA.
DR   RefSeq; YP_135410.1; NC_006396.1.
DR   ProteinModelPortal; Q5V448; -.
DR   GeneID; 3130370; -.
DR   GenomeReviews; AY596297_GR; rrnAC0709.
DR   KEGG; hma:rrnAC0709; -.
DR   NMPDR; fig|272569.1.peg.669; -.
DR   OMA; LRVTACP; -.
DR   ProtClustDB; CLSK511064; -.
DR   BioCyc; HMAR272569:RRNAC0709-MON; -.
DR   GO; GO:0004049; F:anthranilate synthase activity; IEA:EC.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR019999; Anth_synth_I.
DR   InterPro; IPR006805; Anth_synth_I_N.
DR   InterPro; IPR015890; Chorismate-bd_C.
DR   InterPro; IPR010118; Para-NH2Bz/anthranilate_synth.
DR   Gene3D; G3DSA:3.60.120.10; TRPE_1_chor_bd; 1.
DR   Pfam; PF04715; Anth_synt_I_N; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   PRINTS; PR00095; ANTSNTHASEI.
DR   SUPFAM; SSF56322; TRPE_1_chor_bd; 1.
DR   TIGRFAMs; TIGR01824; PabB-clade2; 1.
DR   HOGENOMDNA; HAMAR1_8.PE619; -.
KW   anthranilate synthase component I;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; Lyase; Tryptophan biosynthesis.
SQ   SEQUENCE   489 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQSVETDRTT FTDLAADAHP AARVPVEVRV DVDDPFLAYR RARDETGGVY LATTGGQSGW
     GYFGTAPADF REVDPRAGGT LAALTEFLDG ERLVRGDCDV PYPCGAVGWL SYDVARELES
     LPDSADADRA LPNLQVARYD RFAAWEEPRG ESVTLRVTAC PRVDDFETPE LAYEFGKQHA
     LDLARAAAQG DPSVEDPPVE TDEATFESDC TRESFADRVQ TVKQYIRDGD TFQANVSQRL
     RAPAAVHPVE AFDALRTVNP APYSALLEFP GVDLVSASPE LLLHRDGDRI ETEPIAGTRP
     RGETPDADDR LETDLLDDEK ERAEHAMLVD LERNDLGKVS KFGSVEVSDY RRVDRYSEVM
     HLVSVVEGRL RDGASLQDAI AAVFPGGTIT GAPKPRTMEI IDEVEATRRG PYTGSIGLFG
     FDGRATLNIV IRTLVRYAEE YHLRVGAGVV HDSDPDREYQ ETLDKGRALV NAVDEALGRR
     VDLAMEDQQ
//

If you have problems or comments...

PBIL Back to PBIL home page