(data stored in ACNUC14830 zone)

HOGENOM: HEFEL1_1_PE1010

ID   HEFEL1_1_PE1010                      STANDARD;      PRT;   268 AA.
AC   HEFEL1_1_PE1010; E7ACY1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Shikimate dehydrogenase; EC=1.1.1 25; (HEFEL1_1.PE1010).
GN   Name=aroE; OrderedLocusNames=Hfelis_10150; ORFNames=HFELIS_10150;
OS   HELICOBACTER FELIS ATCC 49179.
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=936155;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HEFEL1_1.PE1010.
CC       Helicobacter felis ATCC 49179, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E7ACY1_HELFC
CC   -!- CATALYTIC ACTIVITY: Shikimate + NADP(+) = 3-dehydroshikimate +
CC       NADPH.
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 4/7.
CC   -!- SIMILARITY: Belongs to the shikimate dehydrogenase family.
CC   -!- GENE_FAMILY: HOG000237875 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E7ACY1; -.
DR   EMBL; FQ670179; CBY83099.1; -; Genomic_DNA.
DR   RefSeq; YP_004073689.1; NC_014810.2.
DR   GeneID; 10050421; -.
DR   GenomeReviews; FQ670179_GR; Hfelis_10150.
DR   KEGG; hfe:Hfelis_10150; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0004764; F:shikimate 5-dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00222; Shikimate_DH_AroE; 1; -.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR011342; Shikimate_DH.
DR   InterPro; IPR013708; Shikimate_DH-bd_N.
DR   InterPro; IPR022893; Shikimate_quinate_DH.
DR   InterPro; IPR006151; Shikm_DH/Glu-tRNA_Rdtase.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Pfam; PF01488; Shikimate_DH; 1.
DR   Pfam; PF08501; Shikimate_dh_N; 1.
DR   TIGRFAMs; TIGR00507; AroE; 1.
DR   HOGENOMDNA; HEFEL1_1.PE1010; -.
KW   shikimate 5-dehydrogenase;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; NADP; Oxidoreductase.
SQ   SEQUENCE   268 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKEKFFGVFG NPIAHSKSPL LHNKAFGDFE KELGFRGHYQ AILLEEGSSL KATFLALNLS
     GANITAPFKE DAYHLSDVQE GQAQAIQALN TWVYEKGRIV GRTTDIEGFY APLKERNFKP
     QKVLVLGAGG SARAVVAGLC AQGVEVHVFN RSSQRLETFY AQGLTCFHPP HFPLESYDLL
     VNTTSAGMDG ATYPLDLDIL KSLLAKAHMA YDLIYSVQTP FLRLAKDIGA EVLDGRAMFI
     AQAALSFGYF CAQKIPYAEI LKSMQEVF
//

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