(data stored in SCRATCH3701 zone)

HOGENOM6: HELP9_1_PE705

ID   HELP9_1_PE705                        STANDARD;      PRT;   828 AA.
AC   HELP9_1_PE705; E1S8K7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (HELP9_1.PE705).
GN   Name=gyrA; OrderedLocusNames=hp908_0711;
OS   HELICOBACTER PYLORI 908.
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=869727;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HELP9_1.PE705.
CC       Helicobacter pylori (strain 908) chromosome, complete sequence.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E1S8K7_HELP9
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E1S8K7; -.
DR   EMBL; CP002184; ADN79837.1; -; Genomic_DNA.
DR   GenomeReviews; CP002184_GR; hp908_0711.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; HELP9_1.PE705; -.
DR   PRODOM; HELP9_1_PE705.
DR   SWISS-2DPAGE; HELP9_1_PE705.
KW   ADN79837.1100028595old_1320000031;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   828 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQDHLVNETK NIVEVGIDSS IEESYLAYSM SVIIGRALPD ARDGLKPVHR RILYAMHELG
     LTSKVAYKKS ARIVGDVIGK YHPHGDTAVY DALVRMAQDF SMRLELVDGQ GNFGSIDGDN
     AAAMRYTEAR MTKASEEILR DIDKDTIDFV PNYDDTLKEP DILPSRLPNL LVNGANGIAV
     GMATSIPPHR IDEIIDALAH VLENPNAELD EILEFVKGPD FPTGGIIYGK AGIVEAYKTG
     RGRVKVRAKV HVEKTKNKEI IVLDEMPFQT NKAKLVEQIS DLAREKQIEG ISEVRDESDR
     EGIRVVIELK RDAMSEIVLN HLYKLTTMET TFSIILLAIY NKEPKIFTLL ELLRLFLNHR
     KTTIIRRTIF ELEKAKARAH ILEGYLIALD NIDEIVRLIK TSPSPEVAKN ALMERFTLSE
     IQSKAILEMR LQRLTGLERD KIKEEYQNLL ELIDDLNGIL KSEDRLNEVV KTELLEVKEQ
     FSSPRRTEIQ ESYESIDTED LIANEPMVVS MSYKGYVKRV DLKAYERQNR GGKGKLSGST
     YEDDFIENFF VANTHDILLF ITNKGQLYHL KVYKIPEASR IAMGKAIVNL ISLAPDEKIM
     ATLSTKDFSD ERSLAFFTKN GVVKRTNLSE FGGNRSYSGI RAIVLDEGDE LVGAKVVDKN
     AKHLLIASHL GIFIKFPLED VREIGRTTRG VRGIKLNEND FVVGAVVISD DSNKLLSVSE
     NGLGKQTLAE AYREQSRGGK GVIGMKLTQK TGNLVSVISV DDENLDLMIL TASAKMIRVS
     IKDIRETGRN ASGVKLINTT DKVVYVNSCP KEEEPENLET SSVQNLFE
//

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