(data stored in SCRATCH3701 zone)

HOGENOM6: HELPG_1_PE639

ID   HELPG_1_PE639                        STANDARD;      PRT;   833 AA.
AC   HELPG_1_PE639; B5Z766;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; (HELPG_1.PE639).
GN   Name=gyrA; OrderedLocusNames=HPG27_657;
OS   HELICOBACTER PYLORI G27.
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=563041;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HELPG_1.PE639.
CC       Helicobacter pylori G27, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:B5Z766_HELPG
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B5Z766; -.
DR   EMBL; CP001173; ACI27415.1; -; Genomic_DNA.
DR   RefSeq; YP_002266281.1; NC_011333.1.
DR   STRING; B5Z766; -.
DR   GeneID; 6963546; -.
DR   GenomeReviews; CP001173_GR; HPG27_657.
DR   KEGG; hpg:HPG27_657; -.
DR   OMA; TSIPPHR; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; HELPG_1.PE639; -.
DR   PRODOM; HELPG_1_PE639.
DR   SWISS-2DPAGE; HELPG_1_PE639.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   833 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQDNSVQDNS VNETKNIVEV GIDSSIEESY LAYSMSVIIG RALPDARDGL KPVHRRILYA
     MHELGLTSKV AYKKSARIVG DVIGKYHPHG DNAVYDALVR MAQDFSMRLE LVDGQGNFGS
     IDGDNAAAMR YTEARMTKAS EEILRDIDKD TIDFVPNYDD TLKEPDILPS RLPNLLVNGA
     NGIAVGMATS IPPHRIDEII DALAHVLENP NAALDEILEF VKGPDFPTGG IIYGKAGIVE
     AYKTGRGRVK VRAKVHVEKT KNKEIIVLDE MPFQTNKAKL VEQISDLARE KQIEGISEVR
     DESDREGIRV VIELKRDAMS EIVLNHLYKL TTMETTFSII LLAIYNKEPK IFTLLELLRL
     FLNHRKTIII RRTIFELEKA KARAHILEGY LIALDNIDEI VQLIKTSQSP EAAKNALMER
     FTLSEIQSKA ILEMRLQRLT GLERDKIKEE YQNLLELIDD LNGILKSEDR LNGVVKTELL
     EVKEQFSSPR HTEIQESYEN IDIEDLIANE PMVVSMSYKG YVKRVDLKAY EKQNRGGKGK
     LSGSTYEDDF IENFFVANTH DILLFITNKG QLYHLKVYKI PEASRIAMGK AIVNLISLAP
     DEKIMATLST KDFSDERSLA FFTKNGVVKR TNLSEFGSNR SYSGIRAIVL DEGDELVSAK
     VVDKNVKHLL IASHLGIFIK FPLEDVREIG RTTRGVKGIR LAENDFVVGA VVISDDGNKL
     LSVSENGLGK QTLAEAYREQ SRGGKGIIGM RLTQKTGNLV SVISVDDENL DLMILTASAK
     MIRVSIKDIR ETGRNASGVK LINTADKVVY VNSCPKEEEP ENLETSSAQN LFE
//

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