(data stored in SCRATCH3701 zone)

HOGENOM6: HELPP_1_PE622

ID   HELPP_1_PE622                        STANDARD;      PRT;   828 AA.
AC   HELPP_1_PE622; E1Q6E4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; (HELPP_1.PE622).
GN   OrderedLocusNames=HPPC_03275;
OS   HELICOBACTER PYLORI PECAN4.
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=765963;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HELPP_1.PE622.
CC       Helicobacter pylori PeCan4 chromosome, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E1Q6E4_HELPP
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E1Q6E4; -.
DR   EMBL; CP002074; ADO06887.1; -; Genomic_DNA.
DR   RefSeq; YP_003926937.1; NC_014555.1.
DR   GeneID; 9785714; -.
DR   GenomeReviews; CP002074_GR; HPPC_03275.
DR   KEGG; hpc:HPPC_03275; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; HELPP_1.PE622; -.
DR   PRODOM; HELPP_1_PE622.
DR   SWISS-2DPAGE; HELPP_1_PE622.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   828 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQDNLISETK NIVEVGIDSS IEESYLAYSM SVIIGRALPD ARDGLKPVHR RILYAMHELG
     LTSKIAYKKS ARIVGDVIGK YHPHGDNAVY GALVRMAQDF SMRLELVDGQ GNFGSIDGDN
     AAAMRYTEAR MTKASEEILR DIDKDTIDFV PNYDDTLKEP DILPSRLPNL LVNGANGIAV
     GMATSIPPHR IDEIIDALVH VLENPNAGLD EILEFVKGPD FPTGGIIYGK AGIIEAYKTG
     RGRVKVRAKV HVEKMKNKEI IVLDEMPFQT NKAKLVEQIS DLAREKQIEG ISEVRDESDR
     EGIRVVIELK RDAMSEIVLN HLYKLTTMET TFSIILLAIY NKEPKIFTLL ELLRLFLNHR
     KTIIIRRTIF ELEKAKARAH ILEGYLIALD NIDEIVRLIK TSQSPEAAKN ALMERFTLSE
     IQSKAILEMR LQRLTGLERD KIKEEYQNLL ELINDLNGIL KSEDRLNEVV KTELLEVKEQ
     FSSQRRTEIQ EAYENIDVED LIANEPMVVS MSYKGYVKRV DLKAYERQNR GGKGKLSGNT
     YEDDFIENFF VANTHDILLF ITNKGQLYHL KVYKIPEASR IAMGKAIVNL ISLAPDEKIM
     ATLSTKDFSD ERSLAFFTKN GVVKRTNLSE FGSNRSYSGI RAIVLDEGDE LVSAKIVDKD
     AKHLLIASYL GIFIKFPLED VREIGRNARG VRGIKLNEND FVVGAVVIND DSNKLLSVSE
     NGLGKQTLAE AYREQSRGGK GIIGMKLTQK TGNLVSVTSV DDENLDLMIL TASAKMIRVS
     IKDIKETIGR NTSGVKLIDT ADKVVYANSC PKEEEPENSE NPPTQLFE
//

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