(data stored in ACNUC22665 zone)

HOGENOM: HORSE5_53_PE9

ID   HORSE5_53_PE9                        STANDARD;      PRT;   347 AA.
AC   HORSE5_53_PE9; P37998;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=T-cell surface antigen CD2;AltName: CD_antigen=CD2;Flags:
DE   Precursor; (HORSE5_53.PE9).
GN   Name=CD2;
OS   EQUUS CABALLUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9796;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HORSE5_53.PE9.
CC       Equus caballus chromosome 5 EquCab2 partial sequence 51574714..52574713
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:CD2_HORSE
CC   -!- FUNCTION: CD2 interacts with lymphocyte function-associated
CC       antigen (LFA-3) to mediate adhesion between T-cells and other cell
CC       types. CD2 is implicated in the triggering of T-cells, the
CC       cytoplasmic domain is implicated in the signaling function.
CC   -!- SUBUNIT: Interacts with PSTPIP1 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
CC       protein.
CC   -!- TISSUE SPECIFICITY: Expressed in spleen and thymus.
CC   -!- SIMILARITY: Contains 1 Ig-like C2-type (immunoglobulin-like)
CC       domain.
CC   -!- SIMILARITY: Contains 1 Ig-like V-type (immunoglobulin-like)
CC       domain.
CC   -!- GENE_FAMILY: HOG000276890 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Equus_caballus;ENSECAG00000019437;ENSECAT00000020758;ENSECAP00000017053.
DR   EMBL; X69884; - ;
DR   UniProtKB/Swiss-Prot; P37998; -.
DR   EMBL; X69884; CAA49511.1; -; mRNA.
DR   PIR; S41638; S41638.
DR   RefSeq; NP_001078903.1; NM_001085434.1.
DR   UniGene; Eca.2146; -.
DR   ProteinModelPortal; P37998; -.
DR   SMR; P37998; 27-124.
DR   MINT; MINT-1769693; -.
DR   STRING; P37998; -.
DR   Ensembl; ENSECAT00000020758; ENSECAP00000017053; ENSECAG00000019437.
DR   GeneID; 100034205; -.
DR   KEGG; ecb:100034205; -.
DR   CTD; 914; -.
DR   GeneTree; ENSGT00390000009232; -.
DR   InParanoid; P37998; -.
DR   OMA; HQQKGPP; -.
DR   OrthoDB; EOG4H9XMK; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008424; Ig_C2-set.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR015631; Signal_lymphocyte_activ_molc.
DR   InterPro; IPR015632; T-cell_sdhesion_molc_CD2.
DR   Gene3D; G3DSA:2.60.40.10; Ig-like_fold; 2.
DR   PANTHER; PTHR12080:SF10; CD2_pre; 1.
DR   PANTHER; PTHR12080; SLAM_related; 1.
DR   Pfam; PF05790; C2-set; 1.
DR   Pfam; PF07686; V-set; 1.
DR   PRINTS; PR01870; CD2ANTIGEN.
DR   PROSITE; PS50835; IG_LIKE; FALSE_NEG.
DR   HOGENOMDNA; HORSE5_53.PE9; -.
KW   ENSECAG000000194375old_1320000031; ENSECAP000000170531old_1320000031;
KW   X69884;
KW   Cell adhesion; Complete proteome; Disulfide bond; Glycoprotein;
KW   Immunoglobulin domain; Membrane; Repeat; Signal; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   347 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNLACKLLAS FLLIFFFSSK GAVSKKNITI LGALERDINL DIPAFQMSEH VEDIQWSKGK
     TKIAKFKNGS MTFQKDKTYE VLKNGTLKIK HLERIHEGTY KVDAYDSDGK NVLEETFHLS
     LLEMVSKPNI SWSCTNTTLT CEVTKGTDFE LKLYLNGRMI QKSPRKVIVY KRASNQIASF
     KCTANNTVSE ESSSVVIRCT EKGLDIYLIS GICGGGIILF VFLALLIFYI SKRKKQNSRR
     NDEELEIRAH KVISEERGRK PHQIPGSTPL NPAASQPPPP PSHRPQAPGH RPQVPGHRPL
     PPGHRVQHQQ QKRPAPTPGT QAHQQKGPPL PRPRVQPKPP RGATENS
//

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