(data stored in ACNUC25930 zone)

HOGENOM: HS10_PE1013

ID   HS10_PE1013                          STANDARD;      PRT;   703 AA.
AC   HS10_PE1013; Q5VTM2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing
DE   protein 9; Short=AGAP-9;AltName: Full=Centaurin-gamma-like family member
DE   6; (HS10.PE1013).
GN   Name=AGAP9; Synonyms=CTGLF6;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS10.PE1013.
CC       Homo sapiens chromosome 10 GRCh37  sequence 1..135524747 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:AGAP9_HUMAN
CC   -!- FUNCTION: Putative GTPase-activating protein (Potential).
CC   -!- MISCELLANEOUS: Encoded by one of the numerous copies of centaurin
CC       gamma-like genes clustered in the q11 region of chromosome 10.
CC   -!- SIMILARITY: Belongs to the centaurin gamma-like family.
CC   -!- SIMILARITY: Contains 1 ANK repeat.
CC   -!- SIMILARITY: Contains 1 Arf-GAP domain.
CC   -!- SIMILARITY: Contains 1 PH domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAH72201.1; Type=Erroneous gene model prediction;
CC   -!- GENE_FAMILY: HOG000007233 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000198035;ENST00000453919;ENSP00000396454.
DR   EMBL; AL591684; - ;
DR   UniProtKB/Swiss-Prot; Q5VTM2; -.
DR   EMBL; AL591684; CAH72201.1; ALT_SEQ; Genomic_DNA.
DR   IPI; IPI00747142; -.
DR   UniGene; Hs.645346; -.
DR   ProteinModelPortal; Q5VTM2; -.
DR   SMR; Q5VTM2; 325-492, 511-701.
DR   PRIDE; Q5VTM2; -.
DR   Ensembl; ENST00000453919; ENSP00000396454; ENSG00000198035.
DR   GeneCards; GC10P048214; -.
DR   HGNC; HGNC:23463; AGAP9.
DR   neXtProt; NX_Q5VTM2; -.
DR   GeneTree; ENSGT00600000084361; -.
DR   CleanEx; HS_AGAP9; -.
DR   Genevestigator; Q5VTM2; -.
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR001164; ArfGAP.
DR   InterPro; IPR011993; PH_type.
DR   InterPro; IPR001849; Pleckstrin_homology.
DR   InterPro; IPR000795; ProtSyn_GTP-bd.
DR   Gene3D; G3DSA:1.25.40.20; ANK; 1.
DR   Gene3D; G3DSA:2.30.29.30; PH_type; 2.
DR   Pfam; PF01412; ArfGap; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF00169; PH; 1.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF57863; ArfGAP; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; FALSE_NEG.
DR   PROSITE; PS50115; ARFGAP; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   HOGENOMDNA; HS10.PE1013; -.
KW   ENSG000001980351755old_1320000031; ENSP000003964547901old_1320000031;
KW   AL591684;
KW   ANK repeat; Complete proteome; GTPase activation; Metal-binding;
KW   Reference proteome; Zinc; Zinc-finger.
SQ   SEQUENCE   703 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MFEDVFSDSG NTGNFDRGKK RRLTIIECGC DINMMIDLAK VADLVLMLID ASFGFEMEMF
     EFLNICQAHG FPKILGVLTH LDSFKHNKQL KKTKKRLKHR FWTEVYQDKV GLTHELVQSL
     ISTYSTIDAK MASSRVTLLS NSKPLGSEAI DNQGVSLEFD QQQGSVCPSE SEIYEAGAED
     RMAGAPMAAA VQPAEVTVEV GEDLHMHQVR DREMPEVVEI RRSNCTNHCD LGDTSSYHTK
     VSTVHIMKKR NGGGSLNNYS SSIPPTPSTS QEDPQFSVPP TANTPTPVCK RSMRWSNLFT
     SEKGSDPDKE RKAPENHADT IGSGRAIPIK QGMLLKRSGK WLKTWKKKYV TLCSNGVLTY
     YSSLGDYMKN IHKKEIDLRT STIKVPGKWP SLATSACAPI SSSKSNGLSK DMDTGLGDSI
     CFSPGISSTT SPKLNPPPSP HANKKKHLKK KSTNNFMIVS ATGQTWHFEA TTYEERDAWV
     QAIQSQILAS LQSCKSSKSK SQLTSQSEAM ALQSIQNMRG NAHCVDCETQ NPKWASLNLG
     VLMCIECSGI HRSFGTRLSR VRSLELDDWP VELRKVMSSI GNELANSIWE GSSQGQTKPS
     IKSTREEKEW WIRSKYEEKL FLAPLPCTEL SLGQQLLRAT TDEDLQTAIL LLAHGSREEV
     NETCGEGDGC TALHLACRKG NVVLEQLLTG WTSWPEMPTG TQR
//

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