(data stored in ACNUC9435 zone)

HOGENOM: HS10_PE1335

ID   HS10_PE1335                          STANDARD;      PRT;   270 AA.
AC   HS10_PE1335; Q96SZ5; B1AL29;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=2-aminoethanethiol dioxygenase; EC=1.13.11 19;AltName:
DE   Full=Cysteamine dioxygenase; (HS10.PE1335).
GN   Name=ADO; Synonyms=C10orf22;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS10.PE1335.
CC       Homo sapiens chromosome 10 GRCh37  sequence 1..135524747 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:AEDO_HUMAN
CC   -!- CATALYTIC ACTIVITY: 2-aminoethanethiol + O(2) = hypotaurine.
CC   -!- COFACTOR: Iron (By similarity).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB55123.1; Type=Erroneous initiation;
CC   -!- WEB RESOURCE: Name=GeneReviews;
CC       URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/C10orf2";
CC   -!- GENE_FAMILY: HOG000037604 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000181915;ENST00000373783;ENSP00000362888.
DR   EMBL; AK027453; - ;
DR   EMBL; AK127694; - ;
DR   EMBL; AL133417; - ;
DR   EMBL; BC018660; - ;
DR   EMBL; BC028589; - ;
DR   EMBL; BC067740; - ;
DR   EMBL; CH471083; - ;
DR   UniProtKB/Swiss-Prot; Q96SZ5; B1AL29; -.
DR   EMBL; AL133417; CAH73826.2; -; Genomic_DNA.
DR   EMBL; CH471083; EAW54235.1; -; Genomic_DNA.
DR   EMBL; BC018660; AAH18660.3; -; mRNA.
DR   EMBL; BC028589; AAH28589.2; -; mRNA.
DR   EMBL; BC067740; AAH67740.2; -; mRNA.
DR   EMBL; AK027453; BAB55123.1; ALT_INIT; mRNA.
DR   IPI; IPI00045939; -.
DR   RefSeq; NP_116193.2; NM_032804.5.
DR   UniGene; Hs.99821; -.
DR   ProteinModelPortal; Q96SZ5; -.
DR   STRING; Q96SZ5; -.
DR   PhosphoSite; Q96SZ5; -.
DR   PRIDE; Q96SZ5; -.
DR   Ensembl; ENST00000373783; ENSP00000362888; ENSG00000181915.
DR   GeneID; 84890; -.
DR   KEGG; hsa:84890; -.
DR   UCSC; uc001jmg.1; human.
DR   CTD; 84890; -.
DR   GeneCards; GC10P058556; -.
DR   H-InvDB; HIX0008860; -.
DR   HGNC; HGNC:23506; ADO.
DR   HPA; HPA039194; -.
DR   HPA; HPA040437; -.
DR   MIM; 611392; gene.
DR   neXtProt; NX_Q96SZ5; -.
DR   GeneTree; ENSGT00390000014082; -.
DR   InParanoid; Q96SZ5; -.
DR   OMA; RIARQAC; -.
DR   OrthoDB; EOG4894N9; -.
DR   NextBio; 75218; -.
DR   ArrayExpress; Q96SZ5; -.
DR   Bgee; Q96SZ5; -.
DR   CleanEx; HS_ADO; -.
DR   Genevestigator; Q96SZ5; -.
DR   GermOnline; ENSG00000181915; Homo sapiens.
DR   GO; GO:0047800; F:cysteamine dioxygenase activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR011051; Cupin_RmlC_type.
DR   InterPro; IPR012864; Cysteamine_dioxygenase.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Gene3D; G3DSA:2.60.120.10; RmlC-like_jellyroll; 1.
DR   Pfam; PF07847; DUF1637; 1.
DR   SUPFAM; SSF51182; RmlC_like_cupin; 1.
DR   HOGENOMDNA; HS10.PE1335; -.
KW   ENSG000001819151755old_1320000031; ENSP000003628887901old_1320000031;
KW   B3KXN9_HUMAN; AK027453; AK127694; AL133417; BC018660; BC028589; BC067740;
KW   CH471083;
KW   Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase;
KW   Polymorphism; Reference proteome.
SQ   SEQUENCE   270 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPRDNMASLI QRIARQACLT FRGSGGGRGA SDRDAASGPE APMQPGFPEN LSKLKSLLTQ
     LRAEDLNIAP RKATLQPLPP NLPPVTYMHI YETDGFSLGV FLLKSGTSIP LHDHPGMHGM
     LKVLYGTVRI SCMDKLDAGG GQRPRALPPE QQFEPPLQPR EREAVRPGVL RSRAEYTEAS
     GPCILTPHRD NLHQIDAVEG PAAFLDILAP PYDPDDGRDC HYYRVLEPVR PKEASSSACD
     LPREVWLLET PQADDFWCEG EPYPGPKVFP
//

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