(data stored in ACNUC30567 zone)

HOGENOM: HS10_PE2946

ID   HS10_PE2946                          STANDARD;      PRT;   740 AA.
AC   HS10_PE2946; Q5JRP2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=ADAM metallopeptidase domain 12 (HS10.PE2946) (Meltrin
DE   alpha);SubName: Full=Uncharacterized protein;Flags: Fragment; .
GN   Name=ADAM12; ORFNames=RP11-295J3.5-003;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS10.PE2946.
CC       Homo sapiens chromosome 10 GRCh37  sequence 1..135524747 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q5JRP2_HUMAN
CC   -!- SIMILARITY: Contains 1 peptidase M12B domain.
CC   -!- GENE_FAMILY: HOG000230883 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000148848;ENST00000368683;ENSP00000357672.
DR   EMBL; AC022015; - ;
DR   EMBL; AC026226; - ;
DR   EMBL; AL589787; - ;
DR   UniProtKB/Swiss-Prot; Q5JRP2; -.
DR   EMBL; AC063963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL691463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL589787; CAI40681.1; -; Genomic_DNA.
DR   EMBL; AC022015; CAI40681.1; JOINED; Genomic_DNA.
DR   EMBL; AC026226; CAI40681.1; JOINED; Genomic_DNA.
DR   IPI; IPI00646614; -.
DR   UniGene; Hs.594537; -.
DR   ProteinModelPortal; Q5JRP2; -.
DR   SMR; Q5JRP2; 208-277.
DR   STRING; Q5JRP2; -.
DR   PRIDE; Q5JRP2; -.
DR   Ensembl; ENST00000448723; ENSP00000391268; ENSG00000148848.
DR   HGNC; HGNC:190; ADAM12.
DR   GeneTree; ENSGT00590000082827; -.
DR   ArrayExpress; Q5JRP2; -.
DR   Bgee; Q5JRP2; -.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR024079; MetalloPept_cat_dom.
DR   InterPro; IPR001590; Peptidase_M12B.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   Gene3D; G3DSA:3.40.390.10; G3DSA:3.40.390.10; 1.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
DR   Pfam; PF01421; Reprolysin; 1.
DR   PROSITE; PS50215; ADAM_MEPRO; 1.
DR   HOGENOMDNA; HS10.PE2946; -.
KW   ENSG000001488481755old_1320000031; ENSP000003576727901old_1320000031;
KW   AC022015; AC026226; AL589787;
KW   Complete proteome; Hydrolase; Metal-binding; Metalloprotease;
KW   Protease; Reference proteome.
SQ   SEQUENCE   740 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAARPLPVSP ARALLLALAG ALLAPCEARG VSLWNQGRAD EVVSASVGSG DLWIPVKSFD
     SKNHPEVLNI RLQRESKELI INLERNEGLI ASSFTETHYL QDGTDVSLAR NYTGHCYYHG
     HVRGYSDSAV SLSTCSGLRG LIVFENESYV LEPMKSATNR YKLFPAKKLK SVRGSCGSHH
     NTPNLAAKNV FPPPSQTWAR RHKRETLKAT KYVELVIVAD NREFQRQGKD LEKVKQRLIE
     IANHVDKFYR PLNIRIVLVG VEVWNDMDKC SVSQDPFTSL HEFLDWRKMK LLPRKSHDNA
     QLVSGVYFQG TTIGMAPIMS MCTADQSGGI VMDHSDNPLG AAVTLAHELG HNFGMNHDTL
     DRGCSCQMAV EKGGCIMNAS TGQGKYPFPM VFSSCSRKDL ETSLEKGMGV CLFNLPEVRE
     SFGGQKCGNR FVEEGEECDC GEPEECMNRC CNATTCTLKP DAVCAHGLCC EDCQLKPAGT
     ACRDSSNSCD LPEFCTGASP HCPANVYLHD GHSCQDVDGY CYNGICQTHE QQCVTLWGPG
     AKPAPGICFE RVNSAGDPYG NCGKVSKSSF AKCEMRDAKC GKIQCQGGAS RPVIGTNAVS
     IETNIPLQQG GRILCRGTHV YLGDDMPDPG LVLAGTKCAD GKICLNRQCQ NISVFGVHEC
     AMQCHGRGVC NNRKNCHCEA HWAPPFCDKF GFGGSTDSGP IRQAGKEARQ EAAESNRERG
     QGQEPVGSQE HASTASLTLI
//

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