(data stored in ACNUC1829 zone)

HOGENOM: HS11_PE132

ID   HS11_PE132                           STANDARD;      PRT;   257 AA.
AC   HS11_PE132; O14817; Q6IAP6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Tetraspanin-4; Short=Tspan-4;AltName: Full=Novel antigen 2;
DE   Short=NAG-2;AltName: Full=Transmembrane 4 superfamily member 7;
DE   (HS11.PE132).
GN   Name=TSPAN4; Synonyms=NAG2, TM4SF7;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS11.PE132.
CC       Homo sapiens chromosome 11 GRCh37  sequence 1..134946516 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:TSN4_HUMAN
CC   -!- SUBUNIT: Forms a complex with integrins.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Expressed in multiple tissues but is absent in
CC       brain, lymphoid cells, and platelets.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC   -!- GENE_FAMILY: HOG000230651 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000214063;ENST00000409531;ENSP00000386899.
DR   EMBL; AF022813; - ;
DR   EMBL; AF054841; - ;
DR   EMBL; AK291089; - ;
DR   EMBL; AP006623; - ;
DR   EMBL; BC000389; - ;
DR   EMBL; BC019314; - ;
DR   EMBL; BC093031; - ;
DR   EMBL; BT006776; - ;
DR   EMBL; CH471158; - ;
DR   EMBL; CR457108; - ;
DR   UniProtKB/Swiss-Prot; O14817; Q6IAP6; -.
DR   EMBL; AF022813; AAC51864.1; -; mRNA.
DR   EMBL; AF054841; AAC69717.1; -; mRNA.
DR   EMBL; AK291089; BAF83778.1; -; mRNA.
DR   EMBL; BT006776; AAP35422.1; -; mRNA.
DR   EMBL; CR457108; CAG33389.1; -; mRNA.
DR   EMBL; CH471158; EAX02409.1; -; Genomic_DNA.
DR   EMBL; BC000389; AAH00389.1; -; mRNA.
DR   EMBL; BC019314; AAH19314.1; -; mRNA.
DR   EMBL; BC093031; AAH93031.1; -; mRNA.
DR   IPI; IPI00024174; -.
DR   PIR; A59265; A59265.
DR   RefSeq; NP_001020405.1; NM_001025234.1.
DR   RefSeq; NP_001020406.1; NM_001025235.1.
DR   RefSeq; NP_001020407.1; NM_001025236.1.
DR   RefSeq; NP_001020408.1; NM_001025237.1.
DR   RefSeq; NP_001020409.1; NM_001025238.1.
DR   RefSeq; NP_001020410.1; NM_001025239.1.
DR   RefSeq; NP_003262.1; NM_003271.4.
DR   UniGene; Hs.654836; -.
DR   ProteinModelPortal; O14817; -.
DR   STRING; O14817; -.
DR   PRIDE; O14817; -.
DR   Ensembl; ENST00000346501; ENSP00000324304; ENSG00000214063.
DR   Ensembl; ENST00000397397; ENSP00000380552; ENSG00000214063.
DR   Ensembl; ENST00000397404; ENSP00000380553; ENSG00000214063.
DR   Ensembl; ENST00000397406; ENSP00000380554; ENSG00000214063.
DR   Ensembl; ENST00000397408; ENSP00000380555; ENSG00000214063.
DR   Ensembl; ENST00000397411; ENSP00000380558; ENSG00000214063.
DR   Ensembl; ENST00000409531; ENSP00000386899; ENSG00000214063.
DR   Ensembl; ENST00000421676; ENSP00000411982; ENSG00000214063.
DR   GeneID; 7106; -.
DR   KEGG; hsa:7106; -.
DR   UCSC; uc001lsd.1; human.
DR   CTD; 7106; -.
DR   GeneCards; GC11P000658; -.
DR   H-InvDB; HIX0018257; -.
DR   HGNC; HGNC:11859; TSPAN4.
DR   HPA; HPA016435; -.
DR   MIM; 602644; gene.
DR   neXtProt; NX_O14817; -.
DR   eggNOG; prNOG08299; -.
DR   GeneTree; ENSGT00590000082914; -.
DR   InParanoid; O14817; -.
DR   OrthoDB; EOG4KD6MV; -.
DR   PhylomeDB; O14817; -.
DR   NextBio; 27801; -.
DR   ArrayExpress; O14817; -.
DR   Bgee; O14817; -.
DR   CleanEx; HS_TSPAN4; -.
DR   Genevestigator; O14817; -.
DR   GermOnline; ENSG00000177769; Homo sapiens.
DR   GO; GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   InterPro; IPR018499; Tetraspanin.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   InterPro; IPR000301; Tetraspanin_subgr.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
DR   HOGENOMDNA; HS11.PE132; -.
KW   ENSG000002140631755old_1320000031; ENSP000003868997901old_1320000031;
KW   A8MVV6_HUMAN; AF022813; AF054841; AK291089; AP006623; BC000389; BC019314;
KW   BT006776; CH471158; CR457108;
KW   Complete proteome; Glycoprotein; Membrane; Polymorphism;
KW   Reference proteome; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   257 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTPRSAGTSA HGAELKRCGM ARACLQAVKY LMFAFNLLFW LGGCGVLGVG IWLAATQGSF
     ATLSSSFPSL SAANLLIITG AFVMAIGFVG CLGAIKENKC LLLTFFLLLL LVFLLEATIA
     ILFFAYTDKI DRYAQQDLKK GLHLYGTQGN VGLTNAWSII QTDFRCCGVS NYTDWFEVYN
     ATRVPDSCCL EFSESCGLHA PGTWWKAPCY ETVKVWLQEN LLAVGIFGLC TALVQILGLT
     FAMTMYCQVV KADTYCA
//

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