(data stored in ACNUC23059 zone)

HOGENOM: HS12_PE2546

ID   HS12_PE2546                          STANDARD;      PRT;   115 AA.
AC   HS12_PE2546; O14519;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Cyclin-dependent kinase 2-associated protein 1;
DE   Short=CDK2-associated protein 1;AltName: Full=Deleted in oral cancer 1;
DE   Short=DOC-1;AltName: Full=Putative oral cancer suppressor; (HS12.PE2546).
GN   Name=CDK2AP1; Synonyms=CDKAP1, DOC1;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS12.PE2546.
CC       Homo sapiens chromosome 12 GRCh37  sequence 1..133841895 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:CDKA1_HUMAN
CC   -!- SIMILARITY: Belongs to the CDK2AP family.
CC   -!- GENE_FAMILY: HOG000035115 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000111328;ENST00000261692;ENSP00000261692.
DR   EMBL; AB006077; - ;
DR   EMBL; AF006484; - ;
DR   EMBL; BC034717; - ;
DR   UniProtKB/Swiss-Prot; O14519; -.
DR   EMBL; AB006077; BAA22937.1; -; mRNA.
DR   EMBL; AF006484; AAC77831.1; -; mRNA.
DR   EMBL; BC034717; AAH34717.1; -; mRNA.
DR   IPI; IPI00022340; -.
DR   RefSeq; NP_004633.1; NM_004642.2.
DR   UniGene; Hs.725139; -.
DR   PDB; 2KW6; NMR; -; A/B=61-115.
DR   PDBsum; 2KW6; -.
DR   ProteinModelPortal; O14519; -.
DR   SMR; O14519; 62-115.
DR   IntAct; O14519; 4.
DR   STRING; O14519; -.
DR   PRIDE; O14519; -.
DR   Ensembl; ENST00000261692; ENSP00000261692; ENSG00000111328.
DR   GeneID; 8099; -.
DR   KEGG; hsa:8099; -.
DR   UCSC; uc001ueq.1; human.
DR   CTD; 8099; -.
DR   GeneCards; GC12M120706; -.
DR   H-InvDB; HIX0201909; -.
DR   HGNC; HGNC:14002; CDK2AP1.
DR   HPA; CAB019377; -.
DR   MIM; 602198; gene.
DR   neXtProt; NX_O14519; -.
DR   PharmGKB; PA26308; -.
DR   eggNOG; prNOG20730; -.
DR   GeneTree; ENSGT00390000006964; -.
DR   InParanoid; O14519; -.
DR   OMA; PQNKYAE; -.
DR   OrthoDB; EOG4DZ1WW; -.
DR   PhylomeDB; O14519; -.
DR   NextBio; 30740; -.
DR   ArrayExpress; O14519; -.
DR   Bgee; O14519; -.
DR   CleanEx; HS_CDK2AP1; -.
DR   Genevestigator; O14519; -.
DR   GermOnline; ENSG00000111328; Homo sapiens.
DR   GO; GO:0005737; C:cytoplasm; TAS:ProtInc.
DR   GO; GO:0005634; C:nucleus; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0000084; P:S phase of mitotic cell cycle; TAS:ProtInc.
DR   InterPro; IPR017266; CDK2-associated_2.
DR   InterPro; IPR019187; Cyclin-dep_kinase2-assoc_pr.
DR   Pfam; PF09806; CDK2AP; 1.
DR   PIRSF; PIRSF037709; CDK2-associated_p2; 1.
DR   HOGENOMDNA; HS12.PE2546; -.
KW   ENSG000001113281755old_1320000031; ENSP000002616927901old_1320000031;
KW   AB006077; AF006484; BC034717;
KW   3D-structure; Cell cycle; Complete proteome; Reference proteome;
KW   Tumor suppressor.
SQ   SEQUENCE   115 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSYKPNLAAH MPAAALNAAG SVHSPSTSMA TSSQYRQLLS DYGPPSLGYT QGTGNSQVPQ
     SKYAELLAII EELGKEIRPT YAGSKSAMER LKRGIIHARG LVRECLAETE RNARS
//

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