(data stored in ACNUC31108 zone)

HOGENOM: HS1_PE2518

ID   HS1_PE2518                           STANDARD;      PRT;   241 AA.
AC   HS1_PE2518; O60635; D3DQ14; O60745; Q5VST0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Tetraspanin-1; Short=Tspan-1;AltName: Full=Tetraspan
DE   NET-1;AltName: Full=Tetraspanin TM4-C; (HS1.PE2518).
GN   Name=TSPAN1;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS1.PE2518.
CC       Homo sapiens chromosome 1 GRCh37  sequence 1..249240621 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:TSN1_HUMAN
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane; Multi-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC   -!- WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology
CC       and Haematology;
CC       URL="http://atlasgeneticsoncology.org/Genes/TSPAN1ID44178ch1p34.html";
CC   -!- GENE_FAMILY: HOG000230651 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000117472;ENST00000372003;ENSP00000361072.
DR   EMBL; AF054838; - ;
DR   EMBL; AF065388; - ;
DR   EMBL; AF133425; - ;
DR   EMBL; AK313774; - ;
DR   EMBL; AL672043; - ;
DR   EMBL; BC007290; - ;
DR   EMBL; BC013404; - ;
DR   EMBL; CH471059; - ;
DR   UniProtKB/Swiss-Prot; O60635; D3DQ14; O60745; Q5VST0; -.
DR   EMBL; AF054838; AAC69714.1; -; mRNA.
DR   EMBL; AF065388; AAC17119.1; -; mRNA.
DR   EMBL; AF133425; AAF08364.1; -; mRNA.
DR   EMBL; AK313774; BAG36512.1; -; mRNA.
DR   EMBL; AL672043; CAH72468.1; -; Genomic_DNA.
DR   EMBL; CH471059; EAX06938.1; -; Genomic_DNA.
DR   EMBL; CH471059; EAX06939.1; -; Genomic_DNA.
DR   EMBL; CH471059; EAX06940.1; -; Genomic_DNA.
DR   EMBL; BC007290; AAH07290.1; -; mRNA.
DR   EMBL; BC013404; AAH13404.1; -; mRNA.
DR   IPI; IPI00030936; -.
DR   PIR; A59262; A59262.
DR   RefSeq; NP_005718.2; NM_005727.3.
DR   UniGene; Hs.38972; -.
DR   ProteinModelPortal; O60635; -.
DR   STRING; O60635; -.
DR   PeptideAtlas; O60635; -.
DR   PRIDE; O60635; -.
DR   Ensembl; ENST00000236130; ENSP00000236130; ENSG00000117472.
DR   Ensembl; ENST00000372003; ENSP00000361072; ENSG00000117472.
DR   GeneID; 10103; -.
DR   KEGG; hsa:10103; -.
DR   UCSC; uc001cpd.2; human.
DR   CTD; 10103; -.
DR   GeneCards; GC01P044755; -.
DR   H-InvDB; HIX0000543; -.
DR   HGNC; HGNC:20657; TSPAN1.
DR   MIM; 613170; gene.
DR   neXtProt; NX_O60635; -.
DR   PharmGKB; PA134938100; -.
DR   eggNOG; prNOG05007; -.
DR   GeneTree; ENSGT00590000082914; -.
DR   InParanoid; O60635; -.
DR   OMA; QCFSFIK; -.
DR   OrthoDB; EOG4T4CWZ; -.
DR   PhylomeDB; O60635; -.
DR   NextBio; 38217; -.
DR   ArrayExpress; O60635; -.
DR   Bgee; O60635; -.
DR   CleanEx; HS_TSPAN1; -.
DR   Genevestigator; O60635; -.
DR   GermOnline; ENSG00000117472; Homo sapiens.
DR   GO; GO:0016021; C:integral to membrane; TAS:ProtInc.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018499; Tetraspanin.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   InterPro; IPR000301; Tetraspanin_subgr.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
DR   HOGENOMDNA; HS1.PE2518; -.
KW   ENSG000001174721755old_1320000031; ENSP000003610727901old_1320000031;
KW   D3DQ14_HUMAN; AF054838; AF065388; AF133425; AK313774; AL672043; BC007290;
KW   CH471059;
KW   Complete proteome; Glycoprotein; Lysosome; Membrane; Polymorphism;
KW   Reference proteome; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   241 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQCFSFIKTM MILFNLLIFL CGAALLAVGI WVSIDGASFL KIFGPLSSSA MQFVNVGYFL
     IAAGVVVFAL GFLGCYGAKT ESKCALVTFF FILLLIFIAE VAAAVVALVY TTMAEHFLTL
     LVVPAIKKDY GSQEDFTQVW NTTMKGLKCC GFTNYTDFED SPYFKENSAF PPFCCNDNVT
     NTANETCTKQ KAHDQKVEGC FNQLLYDIRT NAVTVGGVAA GIGGLELAAM IVSMYLYCNL
     Q
//

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