(data stored in ACNUC7421 zone)

HOGENOM: HS1_PE2704

ID   HS1_PE2704                           STANDARD;      PRT;   292 AA.
AC   HS1_PE2704; Q86YB7; D3DQ36; Q9NV38;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Enoyl-CoA hydratase domain-containing protein 2,
DE   mitochondrial;Flags: Precursor; (HS1.PE2704).
GN   Name=ECHDC2;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS1.PE2704.
CC       Homo sapiens chromosome 1 GRCh37  sequence 1..249240621 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ECHD2_HUMAN
CC   -!- SUBCELLULAR LOCATION: Mitochondrion (Potential).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q86YB7-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q86YB7-2; Sequence=VSP_029177;
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC   -!- GENE_FAMILY: HOG000027939 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000121310;ENST00000371522;ENSP00000360577.
DR   EMBL; AF258590; - ;
DR   EMBL; AK001810; - ;
DR   EMBL; AK302285; - ;
DR   EMBL; BC044574; - ;
DR   UniProtKB/Swiss-Prot; Q86YB7; D3DQ36; Q9NV38; -.
DR   EMBL; AK001810; BAA91922.1; -; mRNA.
DR   EMBL; CH471059; EAX06763.1; -; Genomic_DNA.
DR   EMBL; CH471059; EAX06768.1; -; Genomic_DNA.
DR   EMBL; BC044574; AAH44574.1; -; mRNA.
DR   IPI; IPI00019485; -.
DR   IPI; IPI00384676; -.
DR   RefSeq; NP_001185890.1; NM_001198961.1.
DR   RefSeq; NP_060751.2; NM_018281.3.
DR   UniGene; Hs.476319; -.
DR   HSSP; Q13825; 1HZD.
DR   ProteinModelPortal; Q86YB7; -.
DR   SMR; Q86YB7; 27-292.
DR   IntAct; Q86YB7; 1.
DR   STRING; Q86YB7; -.
DR   PhosphoSite; Q86YB7; -.
DR   PRIDE; Q86YB7; -.
DR   Ensembl; ENST00000371522; ENSP00000360577; ENSG00000121310.
DR   GeneID; 55268; -.
DR   KEGG; hsa:55268; -.
DR   NMPDR; fig|9606.3.peg.1179; -.
DR   UCSC; uc001cup.2; human.
DR   CTD; 55268; -.
DR   GeneCards; GC01M051477; -.
DR   HGNC; HGNC:23408; ECHDC2.
DR   HPA; HPA026731; -.
DR   HPA; HPA026768; -.
DR   neXtProt; NX_Q86YB7; -.
DR   PharmGKB; PA134913726; -.
DR   InParanoid; Q86YB7; -.
DR   OMA; RPPKFVG; -.
DR   OrthoDB; EOG48D0W4; -.
DR   PhylomeDB; Q86YB7; -.
DR   ArrayExpress; Q86YB7; -.
DR   Bgee; Q86YB7; -.
DR   CleanEx; HS_ECHDC2; -.
DR   Genevestigator; Q86YB7; -.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR014748; Crontonase_C.
DR   InterPro; IPR001753; Crotonase_core.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   Gene3D; G3DSA:1.10.12.10; Crontonase_C; 1.
DR   Pfam; PF00378; ECH; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
DR   HOGENOMDNA; HS1.PE2704; -.
KW   ENSG000001213101755old_1320000031; ENSP000003605777901old_1320000031;
KW   B7Z7N0_HUMAN; Q8WY60_HUMAN; AF258590; AK001810; AK302285; BC044574;
KW   Alternative splicing; Complete proteome; Fatty acid metabolism;
KW   Lipid metabolism; Lyase; Mitochondrion; Polymorphism;
KW   Reference proteome; Transit peptide.
SQ   SEQUENCE   292 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLRVLCLLRP WRPLRARGCA SDGAAGGSEI QVRALAGPDQ GITEILMNRP SARNALGNVF
     VSELLETLAQ LREDRQVRVL LFRSGVKGVF CAGADLKERE QMSEAEVGVF VQRLRGLMND
     IAAFPAPTIA AMDGFALGGG LELALACDLR VAASSAVMGL IETTRGLLPG AGGTQRLPRC
     LGVALAKELI FTGRRLSGTE AHVLGLVNHA VAQNEEGDAA YQRARALAQE ILPQAPIAVR
     LGKVAIDRGT EVDIASGMAI EGMCYAQNIP TRDRLEGMAA FREKRTPKFV GK
//

If you have problems or comments...

PBIL Back to PBIL home page