(data stored in ACNUC27670 zone)

HOGENOM: HS1_PE4670

ID   HS1_PE4670                           STANDARD;      PRT;   104 AA.
AC   HS1_PE4670; Q9HCY8; Q5RHT0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Protein S100-A14;AltName: Full=S100 calcium-binding protein
DE   A14; Short=S114; (HS1.PE4670).
GN   Name=S100A14; Synonyms=S100A15;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS1.PE4670.
CC       Homo sapiens chromosome 1 GRCh37  sequence 1..249240621 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:S10AE_HUMAN
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- TISSUE SPECIFICITY: Expressed at highest levels in colon and at
CC       moderate levels in thymus, kidney, liver, small intestine, and
CC       lung. Low expression in heart and no expression is seen in brain,
CC       skeletal muscle, spleen, placenta and peripheral blood leukocytes.
CC   -!- SIMILARITY: Belongs to the S-100 family.
CC   -!- SIMILARITY: Contains 2 EF-hand domains.
CC   -!- GENE_FAMILY: HOG000246968 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000189334;ENST00000368702;ENSP00000357691.
DR   EMBL; AF426828; - ;
DR   EMBL; AY007220; - ;
DR   EMBL; BC005019; - ;
DR   EMBL; BX470102; - ;
DR   UniProtKB/Swiss-Prot; Q9HCY8; Q5RHT0; -.
DR   EMBL; AY007220; AAG01893.1; -; mRNA.
DR   EMBL; AF426828; AAM19206.1; -; Genomic_DNA.
DR   EMBL; BX470102; CAI14759.1; -; Genomic_DNA.
DR   EMBL; BC005019; AAH05019.1; -; mRNA.
DR   IPI; IPI00010214; -.
DR   RefSeq; NP_065723.1; NM_020672.1.
DR   UniGene; Hs.288998; -.
DR   ProteinModelPortal; Q9HCY8; -.
DR   SMR; Q9HCY8; 12-102.
DR   IntAct; Q9HCY8; 1.
DR   MINT; MINT-5002007; -.
DR   STRING; Q9HCY8; -.
DR   PhosphoSite; Q9HCY8; -.
DR   PeptideAtlas; Q9HCY8; -.
DR   PRIDE; Q9HCY8; -.
DR   Ensembl; ENST00000344616; ENSP00000340463; ENSG00000189334.
DR   Ensembl; ENST00000368701; ENSP00000357690; ENSG00000189334.
DR   Ensembl; ENST00000368702; ENSP00000357691; ENSG00000189334.
DR   Ensembl; ENST00000476873; ENSP00000420296; ENSG00000189334.
DR   GeneID; 57402; -.
DR   KEGG; hsa:57402; -.
DR   UCSC; uc001fce.1; human.
DR   CTD; 57402; -.
DR   GeneCards; GC01M124950; -.
DR   H-InvDB; HIX0199952; -.
DR   HGNC; HGNC:18901; S100A14.
DR   HPA; HPA027613; -.
DR   MIM; 607986; gene.
DR   neXtProt; NX_Q9HCY8; -.
DR   PharmGKB; PA134905502; -.
DR   eggNOG; prNOG21170; -.
DR   GeneTree; ENSGT00530000063972; -.
DR   InParanoid; Q9HCY8; -.
DR   OMA; IANLGNC; -.
DR   OrthoDB; EOG4WSWC3; -.
DR   PhylomeDB; Q9HCY8; -.
DR   NextBio; 63504; -.
DR   ArrayExpress; Q9HCY8; -.
DR   Bgee; Q9HCY8; -.
DR   CleanEx; HS_S100A14; -.
DR   Genevestigator; Q9HCY8; -.
DR   GermOnline; ENSG00000189334; Homo sapiens.
DR   GO; GO:0030054; C:cell junction; IDA:HPA.
DR   GO; GO:0015630; C:microtubule cytoskeleton; IDA:HPA.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0042379; F:chemokine receptor binding; IMP:UniProtKB.
DR   GO; GO:0055074; P:calcium ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEP:UniProtKB.
DR   GO; GO:0071624; P:positive regulation of granulocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; IDA:UniProtKB.
DR   InterPro; IPR011992; EF-hand-like_dom.
DR   InterPro; IPR013787; S100_Ca-bd_sub.
DR   Gene3D; G3DSA:1.10.238.10; EF-Hand_type; 1.
DR   Pfam; PF01023; S_100; 1.
DR   PROSITE; PS00018; EF_HAND_1; FALSE_NEG.
DR   PROSITE; PS50222; EF_HAND_2; FALSE_NEG.
DR   PROSITE; PS00303; S100_CABP; FALSE_NEG.
DR   HOGENOMDNA; HS1.PE4670; -.
KW   ENSG000001893341755old_1320000031; ENSP000003576917901old_1320000031;
KW   AF426828; AY007220; BC005019; BX470102;
KW   Calcium; Complete proteome; Cytoplasm; Phosphoprotein;
KW   Reference proteome.
SQ   SEQUENCE   104 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGQCRSANAE DAQEFSDVER AIETLIKNFH QYSVEGGKET LTPSELRDLV TQQLPHLMPS
     NCGLEEKIAN LGSCNDSKLE FRSFWELIGE AAKSVKLERP VRGH
//

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