(data stored in ACNUC16852 zone)

HOGENOM: HS22_PE2380

ID   HS22_PE2380                          STANDARD;      PRT;   1171 AA.
AC   HS22_PE2380; O75132; B2RZH1; Q1ECU0; Q9UGG8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Zinc finger BED domain-containing protein 4; (HS22.PE2380).
GN   Name=ZBED4; Synonyms=KIAA0637;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS22.PE2380.
CC       Homo sapiens chromosome 22 GRCh37  sequence 1..51244566 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ZBED4_HUMAN
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Cytoplasm.
CC   -!- TISSUE SPECIFICITY: Widely expressed with highest levels in
CC       testis, kidney and spinal cord and brain corpus callosum.
CC       Expressed in the retina, found in the cone photoreceptors, Mueller
CC       cells, cone pedicles and in the innermost retinal layer.
CC   -!- SIMILARITY: Contains 4 BED-type zinc fingers.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA31612.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
CC   -!- GENE_FAMILY: HOG000139424 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000100426;ENST00000216268;ENSP00000216268.
DR   EMBL; AB014537; - ;
DR   EMBL; AL117328; - ;
DR   EMBL; BC117670; - ;
DR   EMBL; BC167155; - ;
DR   EMBL; CR456387; - ;
DR   UniProtKB/Swiss-Prot; O75132; B2RZH1; Q1ECU0; Q9UGG8; -.
DR   EMBL; AB014537; BAA31612.2; ALT_INIT; mRNA.
DR   EMBL; CR456387; CAG30273.1; -; mRNA.
DR   EMBL; AL117328; CAB62924.1; -; Genomic_DNA.
DR   EMBL; BC117670; AAI17671.1; -; mRNA.
DR   EMBL; BC167155; AAI67155.1; -; mRNA.
DR   IPI; IPI00006610; -.
DR   PIR; T00380; T00380.
DR   RefSeq; NP_055653.2; NM_014838.2.
DR   UniGene; Hs.475208; -.
DR   ProteinModelPortal; O75132; -.
DR   SMR; O75132; 457-508, 560-613.
DR   IntAct; O75132; 1.
DR   PhosphoSite; O75132; -.
DR   PRIDE; O75132; -.
DR   Ensembl; ENST00000216268; ENSP00000216268; ENSG00000100426.
DR   GeneID; 9889; -.
DR   KEGG; hsa:9889; -.
DR   CTD; 9889; -.
DR   GeneCards; GC22P033189; -.
DR   H-InvDB; HIX0016602; -.
DR   HGNC; HGNC:20721; ZBED4.
DR   MIM; 612552; gene.
DR   neXtProt; NX_O75132; -.
DR   PharmGKB; PA134948378; -.
DR   eggNOG; prNOG09254; -.
DR   GeneTree; ENSGT00530000063354; -.
DR   InParanoid; O75132; -.
DR   OMA; PLDNSKA; -.
DR   OrthoDB; EOG4GXFM1; -.
DR   ArrayExpress; O75132; -.
DR   Bgee; O75132; -.
DR   CleanEx; HS_ZBED4; -.
DR   Genevestigator; O75132; -.
DR   GermOnline; ENSG00000100426; Homo sapiens.
DR   GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   InterPro; IPR008906; HATC.
DR   InterPro; IPR012337; RNaseH-like.
DR   InterPro; IPR003656; Znf_BED_prd.
DR   Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR   Pfam; PF02892; zf-BED; 4.
DR   SMART; SM00614; ZnF_BED; 4.
DR   SUPFAM; SSF53098; RNaseH_fold; 1.
DR   PROSITE; PS50808; ZF_BED; 4.
DR   HOGENOMDNA; HS22.PE2380; -.
KW   ENSG000001004261755old_1320000031; ENSP000002162687901old_1320000031;
KW   AB014537; AL117328; BC117670; BC167155; CR456387;
KW   Complete proteome; Cytoplasm; Metal-binding; Nucleus; Polymorphism;
KW   Reference proteome; Repeat; Zinc; Zinc-finger.
SQ   SEQUENCE   1171 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MENNLKTCPK EDGDFVSDKI KFKIEEEDDD GIPPDSLERM DFKSEQEDMK QTDSGGERAG
     LGGTGCSCKP PGKYLSAESE DDYGALFSQY SSTLYDVAME AVTQSLLSSR NMSSRKKSPA
     WKHFFISPRD STKAICMYCV KEFSRGKNEK DLSTSCLMRH VRRAHPTVLI QENGSVSAVS
     SFPSPSLLLP PQPADAGDLS TILSPIKLVQ KVASKIPSPD RITEESVSVV SSEEISSDMS
     VSEKCGREEA LVGSSPHLPA LHYDEPAENL AEKSLPLPKS TSGSRRRSAV WKHFYLSPLD
     NSKAVCIHCM NEFSRGKNGK DLGTSCLIRH MWRAHRAIVL QENGGTGIPP LYSTPPTLLP
     SLLPPEGELS SVSSSPVKPV RESPSASSSP DRLTEDLQSH LNPGDGLMED VAAFSSSDDI
     GEASASSPEK QQADGLSPRL FESGAIFQQN KKVMKRLKSE VWHHFSLAPM DSLKAECRYC
     GCAISRGKKG DVGTSCLMRH LYRRHPEVVG SQKGFLGASL ANSPYATLAS AESSSSKLTD
     LPTVVTKNNQ VMFPVNSKKT SKLWNHFSIC SADSTKVVCL HCGRTISRGK KPTNLGTSCL
     LRHLQRFHSN VLKTEVSETA RPSSPDTRVP RGTELSGASS FDDTNEKFYD SHPVAKKITS
     LIAEMIALDL QPYSFVDNVG FNRLLEYLKP QYSLPAPSYF SRTAIPGMYD NVKQIIMSHL
     KEAESGVIHF TSGIWMSNQT REYLTLTAHW VSFESPARPR CDDHHCSALL DVSQVDCDYS
     GNSIQKQLEC WWEAWVTSTG LQVGITVTDN ASIGKTLNEG EHSSVQCFSH TVNLIVSEAI
     KSQRMVQNLL SLARKICERV HRSPKAKEKL AELQREYALP QHHLIQDVPS KWSTSFHMLE
     RLIEQKRAIN EMSVECNFRE LISCDQWEVM QSVCRALKPF EAASREMSTQ MSTLSQVIPM
     VHILNRKVEM LFEETMGIDT MLRSLKEAMV SRLSATLHDP RYVFATLLDP RYKASLFTEE
     EAEQYKQDLI RELELMNSTS EDVAASHRCD AGSPSKDSAA EENLWSLVAK VKKKDPREKL
     PEAMVLAYLE EEVLEHSCDP LTYWNLKKAS WPGLSALAVR FLGCPPSIVP SEKLFNTPTE
     NGSLGQSRLM MEHFEKLIFL KVNLPLIYFQ Y
//

If you have problems or comments...

PBIL Back to PBIL home page