(data stored in ACNUC9543 zone)

HOGENOM: HS2_PE2103

ID   HS2_PE2103                           STANDARD;      PRT;   717 AA.
AC   HS2_PE2103; Q8TE96; Q6B017; Q8NAM8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=ATP-dependent RNA helicase DQX1; EC=3.6.4 12;AltName:
DE   Full=DEAQ box polypeptide 1; (HS2.PE2103).
GN   Name=DQX1;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS2.PE2103.
CC       Homo sapiens chromosome 2 GRCh37  sequence 1..243189373 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:DQX1_HUMAN
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q8TE96-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q8TE96-2; Sequence=VSP_024470;
CC       Name=3;
CC         IsoId=Q8TE96-3; Sequence=VSP_024471, VSP_024472;
CC   -!- SIMILARITY: Contains 1 helicase ATP-binding domain.
CC   -!- SIMILARITY: Contains 1 helicase C-terminal domain.
CC   -!- GENE_FAMILY: HOG000175261 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000144045;ENST00000404568;ENSP00000384621.
DR   EMBL; AC005041; - ;
DR   EMBL; AK074337; - ;
DR   EMBL; AK092420; - ;
DR   EMBL; BC075018; - ;
DR   UniProtKB/Swiss-Prot; Q8TE96; Q6B017; Q8NAM8; -.
DR   EMBL; AK074337; BAB85056.1; -; mRNA.
DR   EMBL; AK092420; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AC005041; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC075018; AAH75018.1; -; mRNA.
DR   IPI; IPI00385794; -.
DR   IPI; IPI00843897; -.
DR   IPI; IPI00844595; -.
DR   RefSeq; NP_598376.2; NM_133637.2.
DR   UniGene; Hs.191705; -.
DR   ProteinModelPortal; Q8TE96; -.
DR   SMR; Q8TE96; 20-700.
DR   STRING; Q8TE96; -.
DR   PRIDE; Q8TE96; -.
DR   Ensembl; ENST00000393951; ENSP00000377523; ENSG00000144045.
DR   Ensembl; ENST00000404568; ENSP00000384621; ENSG00000144045.
DR   GeneID; 165545; -.
DR   KEGG; hsa:165545; -.
DR   NMPDR; fig|9606.3.peg.18093; -.
DR   UCSC; uc010ffk.1; human.
DR   CTD; 165545; -.
DR   GeneCards; GC02M074481; -.
DR   H-InvDB; HIX0200286; -.
DR   HGNC; HGNC:20410; DQX1.
DR   neXtProt; NX_Q8TE96; -.
DR   PharmGKB; PA134916600; -.
DR   eggNOG; prNOG10420; -.
DR   GeneTree; ENSGT00550000074627; -.
DR   InParanoid; Q8TE96; -.
DR   OMA; HSFSISK; -.
DR   OrthoDB; EOG4548Z3; -.
DR   NextBio; 88548; -.
DR   ArrayExpress; Q8TE96; -.
DR   Bgee; Q8TE96; -.
DR   CleanEx; HS_DQX1; -.
DR   Genevestigator; Q8TE96; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   InterPro; IPR014001; DEAD-like_helicase.
DR   InterPro; IPR011709; DUF1605.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR001650; Helicase_C.
DR   Pfam; PF04408; HA2; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   HOGENOMDNA; HS2.PE2103; -.
KW   ENSG000001440451755old_1320000031; ENSP000003846217901old_1320000031;
KW   C9J0W1_HUMAN; AC005041; AK074337; AK092420; BC075018;
KW   Alternative splicing; ATP-binding; Complete proteome; Helicase;
KW   Hydrolase; Nucleotide-binding; Nucleus; Reference proteome.
SQ   SEQUENCE   717 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTSQPLRLAE EYGPSPGESE LAVNPFDGLP FSSRYYELLK QRQALPIWAA RFTFLEQLES
     NPTGVVLVSG EPGSGKSTQI PQWCAEFALA RGFQKGQVTV TQPYPLAARS LALRVADEMD
     LTLGHEVGYS IPQEDCTGPN TLLRFCWDRL LLQEVASTRG TGAWGVLVLD EAQERSVASD
     SLQGLLQDAR LEKLPGDLRV VVVTDPALEP KLRAFWGNPP IVHIPREPGE RPSPIYWDTI
     PPDRVEAACQ AVLELCRKEL PGDVLVFLPS EEEISLCCES LSREVESLLL QGLPPRVLPL
     HPDCGRAVQA VYEDMDARKV VVTHWLADFS FSLPSIQHVI DSGLELRSVY NPRIRAEFQV
     LRPISKCQAE ARRLRARGFP PGSCLCLYPK SFLELEAPPL PQPRVCEENL SSLVLLLKRR
     QIAEPGECHF LDQPAPEALM QALEDLDYLA ALDDDGDLSD LGVILSEFPL APELAKALLA
     SCEFDCVDEM LTLAAMLTAA PGFTRPPLSA EEAALRRALE HTDGDHSSLI QVYEAFIQSG
     ADEAWCQARG LNWAALCQAH KLRGELLELM QRIELPLSLP AFGSEQNRRD LQKALVSGYF
     LKVARDTDGT GNYLLLTHKH VAQLSSYCCY RSRRAPARPP PWVLYHNFTI SKDNCLSIVS
     EIQPQMLVEL APPYFLSNLP PSESRDLLNQ LREGMADSTA GSKSSSAQEF RDPCVLQ
//

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