(data stored in ACNUC24361 zone)

HOGENOM: HS3_PE1362

ID   HS3_PE1362                           STANDARD;      PRT;   754 AA.
AC   HS3_PE1362; Q9P0L1; A0PJV3; A8K5H0; Q6WL09; Q96FQ2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Zinc finger protein 167;AltName: Full=Zinc finger protein
DE   448;AltName: Full=Zinc finger protein 64;AltName: Full=Zinc finger
DE   protein with KRAB and SCAN domains 7; (HS3.PE1362).
GN   Name=ZNF167; Synonyms=ZKSCAN7, ZNF448, ZNF64;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS3.PE1362.
CC       Homo sapiens chromosome 3 GRCh37  sequence 1..197962430 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ZN167_HUMAN
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus (Potential).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q9P0L1-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q9P0L1-2; Sequence=VSP_011955, VSP_011956;
CC         Note=No experimental confirmation available;
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family.
CC   -!- SIMILARITY: Contains 13 C2H2-type zinc fingers.
CC   -!- SIMILARITY: Contains 1 KRAB domain.
CC   -!- SIMILARITY: Contains 1 SCAN box domain.
CC   -!- GENE_FAMILY: HOG000234619 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000196345;ENST00000426540;ENSP00000395524.
DR   EMBL; AF154846; - ;
DR   EMBL; AK022800; - ;
DR   EMBL; AK291285; - ;
DR   EMBL; AY280798; - ;
DR   EMBL; BC010555; - ;
DR   EMBL; BC063020; - ;
DR   EMBL; BC127640; - ;
DR   EMBL; BC148260; - ;
DR   EMBL; M88372; - ;
DR   EMBL; M88373; - ;
DR   UniProtKB/Swiss-Prot; Q9P0L1; A0PJV3; A8K5H0; Q6WL09; Q96FQ2; -.
DR   EMBL; AF154846; AAF72104.1; -; mRNA.
DR   EMBL; AY280798; AAQ16302.1; -; mRNA.
DR   EMBL; AK291285; BAF83974.1; -; mRNA.
DR   EMBL; BC010555; AAH10555.1; -; mRNA.
DR   EMBL; BC063020; AAH63020.1; -; mRNA.
DR   EMBL; BC127640; AAI27641.1; -; mRNA.
DR   IPI; IPI00396512; -.
DR   IPI; IPI00479927; -.
DR   PIR; G45193; G45193.
DR   RefSeq; NP_061121.2; NM_018651.2.
DR   RefSeq; NP_079445.1; NM_025169.1.
DR   UniGene; Hs.529512; -.
DR   UniGene; Hs.696570; -.
DR   ProteinModelPortal; Q9P0L1; -.
DR   SMR; Q9P0L1; 48-136, 226-277, 353-748.
DR   IntAct; Q9P0L1; 3.
DR   STRING; Q9P0L1; -.
DR   PRIDE; Q9P0L1; -.
DR   Ensembl; ENST00000273320; ENSP00000273320; ENSG00000196345.
DR   Ensembl; ENST00000426540; ENSP00000395524; ENSG00000196345.
DR   GeneID; 55888; -.
DR   KEGG; hsa:55888; -.
DR   UCSC; uc003cnj.1; human.
DR   CTD; 55888; -.
DR   GeneCards; GC03P044572; -.
DR   HGNC; HGNC:12955; ZNF167.
DR   neXtProt; NX_Q9P0L1; -.
DR   PharmGKB; PA37537; -.
DR   eggNOG; prNOG07749; -.
DR   GeneTree; ENSGT00580000081386; -.
DR   InParanoid; Q9P0L1; -.
DR   OMA; AQEQEIH; -.
DR   OrthoDB; EOG4FJ884; -.
DR   PhylomeDB; Q9P0L1; -.
DR   Reactome; REACT_71; Gene Expression.
DR   NextBio; 61218; -.
DR   ArrayExpress; Q9P0L1; -.
DR   Bgee; Q9P0L1; -.
DR   CleanEx; HS_ZNF167; -.
DR   Genevestigator; Q9P0L1; -.
DR   GermOnline; ENSG00000196345; Homo sapiens.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral reproduction; IEA:InterPro.
DR   InterPro; IPR001909; Krueppel-associated_box.
DR   InterPro; IPR008916; Retrov_capsid_C.
DR   InterPro; IPR003309; Tscrpt_reg_SCAN.
DR   InterPro; IPR007087; Znf_C2H2.
DR   InterPro; IPR015880; Znf_C2H2-like.
DR   InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR   Gene3D; G3DSA:3.30.160.60; Znf_C2H2/integrase_DNA-bd; 13.
DR   Pfam; PF01352; KRAB; 1.
DR   Pfam; PF02023; SCAN; 1.
DR   Pfam; PF00096; zf-C2H2; 13.
DR   SMART; SM00349; KRAB; 1.
DR   SMART; SM00431; SCAN; 1.
DR   SMART; SM00355; ZnF_C2H2; 13.
DR   SUPFAM; SSF109640; Krueppel-associated_box; 1.
DR   SUPFAM; SSF47353; Retrov_capsid_C; 1.
DR   PROSITE; PS50805; KRAB; 1.
DR   PROSITE; PS50804; SCAN_BOX; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 13.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
DR   HOGENOMDNA; HS3.PE1362; -.
KW   ENSG000001963451755old_1320000031; ENSP000003955247901old_1320000031;
KW   A7MAY2_HUMAN; Q16524_HUMAN; Q9H9H9_HUMAN; AF154846; AK022800; AK291285;
KW   BC010555; BC063020; BC127640; BC148260; M88372; M88373;
KW   Alternative splicing; Complete proteome; DNA-binding; Metal-binding;
KW   Nucleus; Polymorphism; Reference proteome; Repeat; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
SQ   SEQUENCE   754 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTTAGRGNLG LIPRSTAFQK QEGRLTVKQE PANQTWGQGS SLQKNYPPVC EIFRLHFRQL
     CYHEMSGPQE ALSRLRELCR WWLMPEVHTK EQILELLVLE QFLSILPGEL RTWVQLHHPE
     SGEEAVAVVE DFQRHLSGSE EVSAPAQKQE MHFEETTALG TTKESPPTSP LSGGSAPGAH
     LEPPYDPGTH HLPSGDFAQC TSPVPTLPQV GNSGDQAGAT VLRMVRPQDT VAYEDLSVDY
     TQKKWKSLTL SQRALQWNMM PENHHSMASL AGENMMKGSE LTPKQEFFKG SESSNRTSGG
     LFGVVPGAAE TGDVCEDTFK ELEGQTSDEE GSRLENDFLE ITDEDKKKST KDRYDKYKEV
     GEHPPLSSSP VEHEGVLKGQ KSYRCDECGK AFNRSSHLIG HQRIHTGEKP YECNECGKTF
     RQTSQLIVHL RTHTGEKPYE CSECGKAYRH SSHLIQHQRL HNGEKPYKCN ECAKAFTQSS
     RLTDHQRTHT GEKPYECNEC GEAFIRSKSL ARHQVLHTGK KPYKCNECGR AFCSNRNLID
     HQRIHTGEKP YECSECGKAF SRSKCLIRHQ SLHTGEKPYK CSECGKAFNQ NSQLIEHERI
     HTGEKPFECS ECGKAFGLSK CLIRHQRLHT GEKPYKCNEC GKSFNQNSHL IIHQRIHTGE
     KPYECNECGK VFSYSSSLMV HQRTHTGEKP YKCNDCGKAF SDSSQLIVHQ RVHTGEKPYE
     CSECGKAFSQ RSTFNHHQRT HTGEKSSGLA WSVS
//

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