(data stored in ACNUC3759 zone)

HOGENOM: HS3_PE2668

ID   HS3_PE2668                           STANDARD;      PRT;   601 AA.
AC   HS3_PE2668; Q8NFY9; Q96JI5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 8;AltName:
DE   Full=T-cell activation kelch repeat protein; Short=TA-KRP; (HS3.PE2668).
GN   Name=KBTBD8; Synonyms=KIAA1842, TAKRP;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS3.PE2668.
CC       Homo sapiens chromosome 3 GRCh37  sequence 1..197962430 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:KBTB8_HUMAN
CC   -!- SIMILARITY: Contains 1 BACK (BTB/Kelch associated) domain.
CC   -!- SIMILARITY: Contains 1 BTB (POZ) domain.
CC   -!- SIMILARITY: Contains 5 Kelch repeats.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI17488.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
CC       Sequence=AAM43839.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
CC   -!- GENE_FAMILY: HOG000113200 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000163376;ENST00000417314;ENSP00000401878.
DR   EMBL; AB058745; - ;
DR   EMBL; AC020655; - ;
DR   EMBL; AF385438; - ;
DR   EMBL; AK096640; - ;
DR   EMBL; BC117487; - ;
DR   UniProtKB/Swiss-Prot; Q8NFY9; Q96JI5; -.
DR   EMBL; AK096640; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AC020655; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AF385438; AAM43839.1; ALT_INIT; mRNA.
DR   EMBL; BC117487; AAI17488.1; ALT_INIT; mRNA.
DR   EMBL; AB058745; BAB47471.1; -; mRNA.
DR   IPI; IPI00168944; -.
DR   RefSeq; NP_115894.2; NM_032505.2.
DR   UniGene; Hs.116665; -.
DR   HSSP; P41182; 1R29.
DR   ProteinModelPortal; Q8NFY9; -.
DR   SMR; Q8NFY9; 25-255, 286-579.
DR   STRING; Q8NFY9; -.
DR   PhosphoSite; Q8NFY9; -.
DR   PRIDE; Q8NFY9; -.
DR   Ensembl; ENST00000417314; ENSP00000401878; ENSG00000163376.
DR   GeneID; 84541; -.
DR   KEGG; hsa:84541; -.
DR   UCSC; uc003dmy.1; human.
DR   CTD; 84541; -.
DR   GeneCards; GC03P067132; -.
DR   H-InvDB; HIX0003432; -.
DR   HGNC; HGNC:30691; KBTBD8.
DR   HPA; HPA041285; -.
DR   neXtProt; NX_Q8NFY9; -.
DR   PharmGKB; PA142671641; -.
DR   eggNOG; prNOG18245; -.
DR   GeneTree; ENSGT00600000084116; -.
DR   InParanoid; Q8NFY9; -.
DR   OMA; VEKGPSN; -.
DR   OrthoDB; EOG4TXBRH; -.
DR   NextBio; 74398; -.
DR   ArrayExpress; Q8NFY9; -.
DR   Bgee; Q8NFY9; -.
DR   CleanEx; HS_KBTBD8; -.
DR   Genevestigator; Q8NFY9; -.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR000210; BTB/POZ-like.
DR   InterPro; IPR011333; BTB/POZ_fold.
DR   InterPro; IPR013069; BTB_POZ.
DR   InterPro; IPR017096; Kelch-like_gigaxonin.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   Gene3D; G3DSA:3.30.710.10; BTB/POZ_fold; 1.
DR   Gene3D; G3DSA:2.120.10.80; Kelch-typ_b-propeller; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 3.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 3.
DR   SUPFAM; SSF54695; BTB/POZ_fold; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   HOGENOMDNA; HS3.PE2668; -.
KW   ENSG000001633761755old_1320000031; ENSP000004018787901old_1320000031;
KW   C9J331_HUMAN; C9JAA6_HUMAN; AB058745; AC020655; AF385438; AK096640;
KW   BC117487;
KW   Complete proteome; Kelch repeat; Polymorphism; Reference proteome;
KW   Repeat.
SQ   SEQUENCE   601 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAASADLSKS SPTPNGIPSS DPASDAMDPF HACSILKQLK TMYDEGQLTD IVVEVDHGKT
     FSCHRNVLAA ISPYFRSMFT SGLTESTQKE VRIVGVEAES MDLVLNYAYT SRVILTEANV
     QALFTAASIF QIPSIQDQCA KYMISHLDPQ NSIGVFIFAD HYGHQELGDR SKEYIRKKFL
     CVTKEQEFLQ LTKDQLISIL DSDDLNVDRE EHVYESIIRW FEHEQNEREV HLPEIFAKCI
     RFPLMEDTFI EKIPPQFAQA IAKSCVEKGP SNTNGCTQRL GMTASEMIIC FDAAHKHSGK
     KQTVPCLDIV TGRVFKLCKP PNDLREVGIL VSPDNDIYIA GGYRPSSSEV SIDHKAENDF
     WMYDHSTNRW LSKPSLLRAR IGCKLVYCCG KMYAIGGRVY EGDGRNSLKS VECYDSRENC
     WTTVCAMPVA MEFHNAVEYK EKIYVLQGEF FLFYEPQKDY WGFLTPMTVP RIQGLAAVYK
     DSIYYIAGTC GNHQRMFTVE AYDIELNKWT RKKDFPCDQS INPYLKLVLF QNKLHLFVRA
     TQVTVEEHVF RTSRKNSLYQ YDDIADQWMK VYETPDRLWD LGRHFECAVA KLYPQCLQKV
     L
//

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