(data stored in ACNUC13479 zone)

HOGENOM: HS3_PE4172

ID   HS3_PE4172                           STANDARD;      PRT;   271 AA.
AC   HS3_PE4172; Q9Y5M8; Q6P595; Q8N2D8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Signal recognition particle receptor subunit beta;
DE   Short=SR-beta;AltName: Full=Protein APMCF1; (HS3.PE4172).
GN   Name=SRPRB; ORFNames=PSEC0230;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS3.PE4172.
CC       Homo sapiens chromosome 3 GRCh37  sequence 1..197962430 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:SRPRB_HUMAN
CC   -!- FUNCTION: Component of the SRP (signal recognition particle)
CC       receptor. Ensures, in conjunction with the signal recognition
CC       particle, the correct targeting of the nascent secretory proteins
CC       to the endoplasmic reticulum membrane system. Has GTPase activity.
CC       May mediate the membrane association of SRPR (By similarity).
CC   -!- SUBUNIT: Heterodimer with SRPR (By similarity).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the SRP receptor beta subunit family.
CC   -!- GENE_FAMILY: HOG000241847 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000144867;ENST00000273406;ENSP00000273406.
DR   EMBL; AC080128; - ;
DR   EMBL; AF086914; - ;
DR   EMBL; AF141882; - ;
DR   EMBL; AK027525; - ;
DR   EMBL; AK075531; - ;
DR   EMBL; BC063001; - ;
DR   EMBL; BC065299; - ;
DR   EMBL; CH471052; - ;
DR   UniProtKB/Swiss-Prot; Q9Y5M8; Q6P595; Q8N2D8; -.
DR   EMBL; AF141882; AAD34888.3; -; mRNA.
DR   EMBL; AK027525; BAB55176.1; -; mRNA.
DR   EMBL; AK075531; BAC11675.1; -; mRNA.
DR   EMBL; BC063001; AAH63001.1; -; mRNA.
DR   EMBL; BC065299; AAH65299.1; -; mRNA.
DR   IPI; IPI00295098; -.
DR   RefSeq; NP_067026.3; NM_021203.3.
DR   UniGene; Hs.12152; -.
DR   ProteinModelPortal; Q9Y5M8; -.
DR   SMR; Q9Y5M8; 65-271.
DR   IntAct; Q9Y5M8; 9.
DR   MINT; MINT-1410114; -.
DR   STRING; Q9Y5M8; -.
DR   PhosphoSite; Q9Y5M8; -.
DR   PeptideAtlas; Q9Y5M8; -.
DR   PRIDE; Q9Y5M8; -.
DR   Ensembl; ENST00000273406; ENSP00000273406; ENSG00000144867.
DR   Ensembl; ENST00000466490; ENSP00000418401; ENSG00000144867.
DR   GeneID; 58477; -.
DR   KEGG; hsa:58477; -.
DR   CTD; 58477; -.
DR   GeneCards; GC03P130882; -.
DR   HGNC; HGNC:24085; SRPRB.
DR   HPA; HPA011173; -.
DR   neXtProt; NX_Q9Y5M8; -.
DR   GeneTree; ENSGT00510000048347; -.
DR   InParanoid; Q9Y5M8; -.
DR   OMA; TLVFWKL; -.
DR   OrthoDB; EOG42Z4QX; -.
DR   PhylomeDB; Q9Y5M8; -.
DR   Reactome; REACT_15380; Diabetes pathways.
DR   NextBio; 64918; -.
DR   ArrayExpress; Q9Y5M8; -.
DR   Bgee; Q9Y5M8; -.
DR   CleanEx; HS_SRPRB; -.
DR   Genevestigator; Q9Y5M8; -.
DR   GermOnline; ENSG00000144867; Homo sapiens.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR024156; Small_GTPase_ARF.
DR   InterPro; IPR019009; SRP_receptor_beta_su.
DR   Pfam; PF09439; SRPRB; 1.
DR   HOGENOMDNA; HS3.PE4172; -.
KW   ENSG000001448671755old_1320000031; ENSP000002734067901old_1320000031;
KW   C9J5Z8_HUMAN; Q549N5_HUMAN; AC080128; AF086914; AF141882; AK027525;
KW   BC063001; BC065299; CH471052;
KW   Complete proteome; Endoplasmic reticulum; GTP-binding; Membrane;
KW   Nucleotide-binding; Polymorphism; Receptor; Reference proteome;
KW   Transmembrane; Transmembrane helix.
SQ   SEQUENCE   271 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MASADSRRVA DGGGAGGTFQ PYLDTLRQEL QQTDPTLLSV VVAVLAVLLT LVFWKLIRSR
     RSSQRAVLLV GLCDSGKTLL FVRLLTGLYR DTQTSITDSC AVYRVNNNRG NSLTLIDLPG
     HESLRLQFLE RFKSSARAIV FVVDSAAFQR EVKDVAEFLY QVLIDSMGLK NTPSFLIACN
     KQDIAMAKSA KLIQQQLEKE LNTLRVTRSA APSTLDSSST APAQLGKKGK EFEFSQLPLK
     VEFLECSAKG GRGDVGSADI QDLEKWLAKI A
//

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