(data stored in ACNUC4305 zone)

HOGENOM: HS3_PE4631

ID   HS3_PE4631                           STANDARD;      PRT;   202 AA.
AC   HS3_PE4631; P30408; Q6IB51;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Transmembrane 4 L6 family member 1;AltName: Full=Membrane
DE   component chromosome 3 surface marker 1;AltName: Full=Tumor-associated
DE   antigen L6; (HS3.PE4631).
GN   Name=TM4SF1; Synonyms=M3S1, TAAL6;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS3.PE4631.
CC       Homo sapiens chromosome 3 GRCh37  sequence 1..197962430 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:T4S1_HUMAN
CC   -!- SUBUNIT: Present in high molecular weight complexes in tumor
CC       cells.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Highly expressed in lung, breast, colon and
CC       ovarian carcinomas. It is also present on some normal cells,
CC       endothelial cells in particular.
CC   -!- SIMILARITY: Belongs to the L6 tetraspanin family.
CC   -!- GENE_FAMILY: HOG000030899 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000169908;ENST00000305366;ENSP00000304277.
DR   EMBL; BC008442; - ;
DR   EMBL; BC010166; - ;
DR   EMBL; CR456953; - ;
DR   EMBL; M90657; - ;
DR   UniProtKB/Swiss-Prot; P30408; Q6IB51; -.
DR   EMBL; M90657; AAA36158.1; -; mRNA.
DR   EMBL; CR456953; CAG33234.1; -; mRNA.
DR   EMBL; BC008442; AAH08442.1; -; mRNA.
DR   EMBL; BC010166; AAH10166.1; -; mRNA.
DR   IPI; IPI00744287; -.
DR   PIR; A42926; A42926.
DR   RefSeq; NP_055035.1; NM_014220.2.
DR   UniGene; Hs.351316; -.
DR   ProteinModelPortal; P30408; -.
DR   IntAct; P30408; 5.
DR   MINT; MINT-1371524; -.
DR   STRING; P30408; -.
DR   PRIDE; P30408; -.
DR   Ensembl; ENST00000305366; ENSP00000304277; ENSG00000169908.
DR   GeneID; 4071; -.
DR   KEGG; hsa:4071; -.
DR   UCSC; uc003exb.1; human.
DR   CTD; 4071; -.
DR   GeneCards; GC03M146458; -.
DR   H-InvDB; HIX0021987; -.
DR   HGNC; HGNC:11853; TM4SF1.
DR   HPA; CAB002760; -.
DR   HPA; HPA002823; -.
DR   MIM; 191155; gene.
DR   neXtProt; NX_P30408; -.
DR   PharmGKB; PA36554; -.
DR   eggNOG; prNOG13819; -.
DR   GeneTree; ENSGT00390000010992; -.
DR   OrthoDB; EOG4XWG02; -.
DR   PhylomeDB; P30408; -.
DR   NextBio; 15960; -.
DR   ArrayExpress; P30408; -.
DR   Bgee; P30408; -.
DR   CleanEx; HS_TM4SF1; -.
DR   Genevestigator; P30408; -.
DR   GermOnline; ENSG00000169908; Homo sapiens.
DR   GO; GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.
DR   InterPro; IPR008661; L6_membrane.
DR   Pfam; PF05805; L6_membrane; 1.
DR   HOGENOMDNA; HS3.PE4631; -.
KW   ENSG000001699081755old_1320000031; ENSP000003042777901old_1320000031;
KW   BC008442; BC010166; CR456953; M90657;
KW   Complete proteome; Glycoprotein; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
SQ   SEQUENCE   202 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCYGKCARCI GHSLVGLALL CIAANILLYF PNGETKYASE NHLSRFVWFF SGIVGGGLLM
     LLPAFVFIGL EQDDCCGCCG HENCGKRCAM LSSVLAALIG IAGSGYCVIV AALGLAEGPL
     CLDSLGQWNY TFASTEGQYL LDTSTWSECT EPKHIVEWNV SLFSILLALG GIEFILCLIQ
     VINGVLGGIC GFCCSHQQQY DC
//

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