(data stored in ACNUC4305 zone)

HOGENOM: HS3_PE4636

ID   HS3_PE4636                           STANDARD;      PRT;   202 AA.
AC   HS3_PE4636; P48230; B2RDA4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Transmembrane 4 L6 family member 4;AltName: Full=Intestine
DE   and liver tetraspan membrane protein; Short=IL-TMP; (HS3.PE4636).
GN   Name=TM4SF4; Synonyms=ILTMP;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS3.PE4636.
CC       Homo sapiens chromosome 3 GRCh37  sequence 1..197962430 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:T4S4_HUMAN
CC   -!- FUNCTION: Regulates the adhesive and proliferative status of
CC       intestinal epithelial cells. Can mediate density-dependent cell
CC       proliferation.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Jejunum and liver.
CC   -!- PTM: N-glycosylated. Glycosylation is required for the growth
CC       inhibitory effect.
CC   -!- SIMILARITY: Belongs to the L6 tetraspanin family.
CC   -!- GENE_FAMILY: HOG000030899 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000169903;ENST00000305354;ENSP00000305852.
DR   EMBL; AK055577; - ;
DR   EMBL; AK315464; - ;
DR   EMBL; BC001386; - ;
DR   EMBL; BT007430; - ;
DR   EMBL; CH471052; - ;
DR   EMBL; U31449; - ;
DR   UniProtKB/Swiss-Prot; P48230; B2RDA4; -.
DR   EMBL; U31449; AAA74745.1; -; mRNA.
DR   EMBL; BT007430; AAP36098.1; -; mRNA.
DR   EMBL; AK315464; BAG37851.1; -; mRNA.
DR   EMBL; CH471052; EAW78871.1; -; Genomic_DNA.
DR   EMBL; BC001386; AAH01386.1; -; mRNA.
DR   IPI; IPI00008779; -.
DR   RefSeq; NP_004608.1; NM_004617.3.
DR   UniGene; Hs.133527; -.
DR   ProteinModelPortal; P48230; -.
DR   STRING; P48230; -.
DR   PRIDE; P48230; -.
DR   Ensembl; ENST00000305354; ENSP00000305852; ENSG00000169903.
DR   GeneID; 7104; -.
DR   KEGG; hsa:7104; -.
DR   NMPDR; fig|9606.3.peg.23340; -.
DR   UCSC; uc003exd.1; human.
DR   CTD; 7104; -.
DR   GeneCards; GC03P146564; -.
DR   H-InvDB; HIX0003764; -.
DR   HGNC; HGNC:11856; TM4SF4.
DR   MIM; 606567; gene.
DR   neXtProt; NX_P48230; -.
DR   eggNOG; prNOG14879; -.
DR   GeneTree; ENSGT00390000010992; -.
DR   InParanoid; P48230; -.
DR   OMA; WYFGGIL; -.
DR   OrthoDB; EOG46Q6TR; -.
DR   PhylomeDB; P48230; -.
DR   NextBio; 27793; -.
DR   ArrayExpress; P48230; -.
DR   Bgee; P48230; -.
DR   CleanEx; HS_TM4SF4; -.
DR   Genevestigator; P48230; -.
DR   GermOnline; ENSG00000169903; Homo sapiens.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008661; L6_membrane.
DR   Pfam; PF05805; L6_membrane; 1.
DR   HOGENOMDNA; HS3.PE4636; -.
KW   ENSG000001699031755old_1320000031; ENSP000003058527901old_1320000031;
KW   B3KP26_HUMAN; AK055577; AK315464; BC001386; BT007430; CH471052; U31449;
KW   Complete proteome; Glycoprotein; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
SQ   SEQUENCE   202 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCTGGCARCL GGTLIPLAFF GFLANILLFF PGGKVIDDND HLSQEIWFFG GILGSGVLMI
     FPALVFLGLK NNDCCGCCGN EGCGKRFAMF TSTIFAVVGF LGAGYSFIIS AISINKGPKC
     LMANSTWGYP FHDGDYLNDE ALWNKCREPL NVVPWNLTLF SILLVVGGIQ MVLCAIQVVN
     GLLGTLCGDC QCCGCCGGDG PV
//

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