(data stored in ACNUC10243 zone)

HOGENOM: HS5_PE2484

ID   HS5_PE2484                           STANDARD;      PRT;   305 AA.
AC   HS5_PE2484; Q13151; Q6IB18;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A0; Short=hnRNP A0;
DE   (HS5.PE2484).
GN   Name=HNRNPA0; Synonyms=HNRPA0;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS5.PE2484.
CC       Homo sapiens chromosome 5 GRCh37  sequence 1..180905260 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ROA0_HUMAN
CC   -!- FUNCTION: This protein is a component of ribonucleosomes.
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity). Note=Component of
CC       ribonucleosomes (By similarity).
CC   -!- PTM: Arg-291 is dimethylated, probably to asymmetric
CC       dimethylarginine.
CC   -!- SIMILARITY: Contains 2 RRM (RNA recognition motif) domains.
CC   -!- GENE_FAMILY: HOG000234442 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000177733;ENST00000314940;ENSP00000316042.
DR   EMBL; BC001008; - ;
DR   EMBL; BC007271; - ;
DR   EMBL; BC009284; - ;
DR   EMBL; BC011972; - ;
DR   EMBL; BC012980; - ;
DR   EMBL; BC018949; - ;
DR   EMBL; BC019271; - ;
DR   EMBL; BC028976; - ;
DR   EMBL; BC030249; - ;
DR   EMBL; CH471062; - ;
DR   EMBL; CR456986; - ;
DR   EMBL; U23803; - ;
DR   UniProtKB/Swiss-Prot; Q13151; Q6IB18; -.
DR   EMBL; U23803; AAA65094.1; -; mRNA.
DR   EMBL; CR456986; CAG33267.1; -; mRNA.
DR   EMBL; CH471062; EAW62182.1; -; Genomic_DNA.
DR   EMBL; BC001008; AAH01008.1; -; mRNA.
DR   EMBL; BC007271; AAH07271.1; -; mRNA.
DR   EMBL; BC009284; AAH09284.1; -; mRNA.
DR   EMBL; BC011972; AAH11972.1; -; mRNA.
DR   EMBL; BC012980; AAH12980.1; -; mRNA.
DR   EMBL; BC018949; AAH18949.1; -; mRNA.
DR   EMBL; BC019271; AAH19271.1; -; mRNA.
DR   EMBL; BC028976; AAH28976.1; -; mRNA.
DR   EMBL; BC030249; AAH30249.1; -; mRNA.
DR   IPI; IPI00011913; -.
DR   RefSeq; NP_006796.1; NM_006805.3.
DR   UniGene; Hs.645902; -.
DR   UniGene; Hs.96996; -.
DR   ProteinModelPortal; Q13151; -.
DR   SMR; Q13151; 2-181.
DR   IntAct; Q13151; 10.
DR   MINT; MINT-5001237; -.
DR   STRING; Q13151; -.
DR   PhosphoSite; Q13151; -.
DR   SWISS-2DPAGE; Q13151; -.
DR   REPRODUCTION-2DPAGE; Q13151; -.
DR   PeptideAtlas; Q13151; -.
DR   PRIDE; Q13151; -.
DR   Ensembl; ENST00000314940; ENSP00000316042; ENSG00000177733.
DR   GeneID; 10949; -.
DR   KEGG; hsa:10949; -.
DR   UCSC; uc003lbt.1; human.
DR   CTD; 10949; -.
DR   GeneCards; GC05M132277; -.
DR   H-InvDB; HIX0005201; -.
DR   HGNC; HGNC:5030; HNRNPA0.
DR   HPA; HPA036569; -.
DR   MIM; 609409; gene.
DR   neXtProt; NX_Q13151; -.
DR   PharmGKB; PA162391106; -.
DR   eggNOG; prNOG08228; -.
DR   GeneTree; ENSGT00560000076532; -.
DR   InParanoid; Q13151; -.
DR   OMA; PKEDIHA; -.
DR   OrthoDB; EOG4W6NX4; -.
DR   PhylomeDB; Q13151; -.
DR   Reactome; REACT_1675; mRNA Processing.
DR   Reactome; REACT_71; Gene Expression.
DR   NextBio; 41601; -.
DR   ArrayExpress; Q13151; -.
DR   Bgee; Q13151; -.
DR   CleanEx; HS_HNRNPA0; -.
DR   Genevestigator; Q13151; -.
DR   GermOnline; ENSG00000177733; Homo sapiens.
DR   GO; GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; TAS:ProtInc.
DR   GO; GO:0005654; C:nucleoplasm; TAS:Reactome.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait.
DR   InterPro; IPR000504; RRM_dom.
DR   Gene3D; G3DSA:3.30.70.330; a_b_plait_nuc_bd; 2.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   PROSITE; PS50102; RRM; 2.
DR   HOGENOMDNA; HS5.PE2484; -.
KW   ENSG000001777331755old_1320000031; ENSP000003160427901old_1320000031;
KW   BC001008; BC007271; BC009284; BC011972; BC012980; BC018949; BC019271;
KW   BC030249; CH471062; CR456986; U23803;
KW   Acetylation; Complete proteome; Direct protein sequencing;
KW   Methylation; Nucleus; Phosphoprotein; Reference proteome; Repeat;
KW   Ribonucleoprotein; RNA-binding.
SQ   SEQUENCE   305 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MENSQLCKLF IGGLNVQTSE SGLRGHFEAF GTLTDCVVVV NPQTKRSRCF GFVTYSNVEE
     ADAAMAASPH AVDGNTVELK RAVSREDSAR PGAHAKVKKL FVGGLKGDVA EGDLIEHFSQ
     FGTVEKAEII ADKQSGKKRG FGFVYFQNHD AADKAAVVKF HPIQGHRVEV KKAVPKEDIY
     SGGGGGGSRS SRGGRGGRGR GGGRDQNGLS KGGGGGYNSY GGYGGGGGGG YNAYGGGGGG
     SSYGGSDYGN GFGGFGSYSQ HQSSYGPMKS GGGGGGGGSS WGGRSNSGPY RGGYGGGGGY
     GGSSF
//

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