(data stored in ACNUC24361 zone)

HOGENOM: HS6_PE627

ID   HS6_PE627                            STANDARD;      PRT;   485 AA.
AC   HS6_PE627; P49910;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Zinc finger protein 165;AltName: Full=Cancer/testis antigen
DE   53; Short=CT53;AltName: Full=LD65;AltName: Full=Zinc finger and SCAN
DE   domain-containing protein 7; (HS6.PE627).
GN   Name=ZNF165; Synonyms=ZPF165, ZSCAN7;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS6.PE627.
CC       Homo sapiens chromosome 6 GRCh37  sequence 1..171055067 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ZN165_HUMAN
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- INTERACTION:
CC       P13994:CCDC130; NbExp=2; IntAct=EBI-741694, EBI-716093;
CC       O14641:DVL2; NbExp=2; IntAct=EBI-741694, EBI-740850;
CC       Q01844:EWSR1; NbExp=2; IntAct=EBI-741694, EBI-739737;
CC   -!- SUBCELLULAR LOCATION: Nucleus (Potential).
CC   -!- TISSUE SPECIFICITY: Expressed specifically in testis.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family.
CC   -!- SIMILARITY: Contains 6 C2H2-type zinc fingers.
CC   -!- SIMILARITY: Contains 1 SCAN box domain.
CC   -!- GENE_FAMILY: HOG000234619 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000197279;ENST00000377325;ENSP00000366542.
DR   EMBL; AK292371; - ;
DR   EMBL; AL121944; - ;
DR   EMBL; AY083664; - ;
DR   EMBL; AY366500; - ;
DR   EMBL; BC026092; - ;
DR   EMBL; BC037779; - ;
DR   EMBL; CH471081; - ;
DR   EMBL; U78722; - ;
DR   EMBL; U88084; - ;
DR   EMBL; U88085; - ;
DR   EMBL; U88086; - ;
DR   EMBL; X84801; - ;
DR   UniProtKB/Swiss-Prot; P49910; -.
DR   EMBL; X84801; CAA59268.1; -; mRNA.
DR   EMBL; U78722; AAC51658.1; -; mRNA.
DR   EMBL; U88086; AAD04755.1; -; Genomic_DNA.
DR   EMBL; U88084; AAD04755.1; JOINED; Genomic_DNA.
DR   EMBL; U88085; AAD04755.1; JOINED; Genomic_DNA.
DR   EMBL; AL121944; CAB92080.1; -; Genomic_DNA.
DR   EMBL; BC026092; AAH26092.1; -; mRNA.
DR   IPI; IPI00029075; -.
DR   PIR; S52411; S52411.
DR   RefSeq; NP_003438.1; NM_003447.3.
DR   UniGene; Hs.535177; -.
DR   UniGene; Hs.55481; -.
DR   ProteinModelPortal; P49910; -.
DR   SMR; P49910; 46-132, 288-484.
DR   IntAct; P49910; 12.
DR   STRING; P49910; -.
DR   PRIDE; P49910; -.
DR   Ensembl; ENST00000252206; ENSP00000252206; ENSG00000197279.
DR   Ensembl; ENST00000377325; ENSP00000366542; ENSG00000197279.
DR   GeneID; 7718; -.
DR   KEGG; hsa:7718; -.
DR   UCSC; uc003nkg.1; human.
DR   CTD; 7718; -.
DR   GeneCards; GC06P027856; -.
DR   HGNC; HGNC:12953; ZNF165.
DR   MIM; 600834; gene.
DR   neXtProt; NX_P49910; -.
DR   PharmGKB; PA37535; -.
DR   eggNOG; prNOG12406; -.
DR   InParanoid; P49910; -.
DR   OMA; THQKSCK; -.
DR   OrthoDB; EOG4QRH3V; -.
DR   PhylomeDB; P49910; -.
DR   NextBio; 29912; -.
DR   ArrayExpress; P49910; -.
DR   Bgee; P49910; -.
DR   CleanEx; HS_ZNF165; -.
DR   Genevestigator; P49910; -.
DR   GermOnline; ENSG00000197279; Homo sapiens.
DR   GO; GO:0005634; C:nucleus; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral reproduction; IEA:InterPro.
DR   InterPro; IPR008916; Retrov_capsid_C.
DR   InterPro; IPR003309; Tscrpt_reg_SCAN.
DR   InterPro; IPR007087; Znf_C2H2.
DR   InterPro; IPR015880; Znf_C2H2-like.
DR   InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR   Gene3D; G3DSA:3.30.160.60; Znf_C2H2/integrase_DNA-bd; 6.
DR   Pfam; PF02023; SCAN; 1.
DR   Pfam; PF00096; zf-C2H2; 5.
DR   SMART; SM00431; SCAN; 1.
DR   SMART; SM00355; ZnF_C2H2; 6.
DR   SUPFAM; SSF47353; Retrov_capsid_C; 1.
DR   PROSITE; PS50804; SCAN_BOX; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 5.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
DR   HOGENOMDNA; HS6.PE627; -.
KW   ENSG000001972791755old_1320000031; ENSP000003665427901old_1320000031;
KW   A8K8K6_HUMAN; Q53Z40_HUMAN; Q8IY56_HUMAN; AK292371; AL121944; AY083664;
KW   BC026092; BC037779; CH471081; U78722; U88084; U88085; U88086; X84801;
KW   Complete proteome; DNA-binding; Metal-binding; Nucleus;
KW   Reference proteome; Repeat; Transcription; Transcription regulation;
KW   Zinc; Zinc-finger.
SQ   SEQUENCE   485 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MATEPKKAAA QNSPEDEGLL IVKIEEEEFI HGQDTCLQRS ELLKQELCRQ LFRQFCYQDS
     PGPREALSRL RELCCQWLKP EIHTKEQILE LLVLEQFLTI LPGDLQAWVH EHYPESGEEA
     VTILEDLERG TDEAVLQVQA HEHGQEIFQK KVSPPGPALN VKLQPVETKA HFDSSEPQLL
     WDCDNESENS RSMPKLEIFE KIESQRIISG RISGYISEAS GESQDICKSA GRVKRQWEKE
     SGESQRLSSA QDEGFGKILT HKNTVRGEII SHDGCERRLN LNSNEFTHQK SCKHGTCDQS
     FKWNSDFINH QIIYAGEKNH QYGKSFKSPK LAKHAAVFSG DKTHQCNECG KAFRHSSKLA
     RHQRIHTGER CYECNECGKS FAESSDLTRH RRIHTGERPF GCKECGRAFN LNSHLIRHQR
     IHTREKPYEC SECGKTFRVS SHLIRHFRIH TGEKPYECSE CGRAFSQSSN LSQHQRIHMR
     ENLLM
//

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