(data stored in ACNUC24361 zone)

HOGENOM: HS7_PE2584

ID   HS7_PE2584                           STANDARD;      PRT;   839 AA.
AC   HS7_PE2584; Q9Y2L8; A4D280; D6W5S9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 5;AltName:
DE   Full=Zinc finger protein 95 homolog; Short=Zfp-95; (HS7.PE2584).
GN   Name=ZKSCAN5; Synonyms=KIAA1015, ZFP95;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS7.PE2584.
CC       Homo sapiens chromosome 7 GRCh37  sequence 1..159128663 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ZKSC5_HUMAN
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus (Potential).
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family.
CC   -!- SIMILARITY: Contains 13 C2H2-type zinc fingers.
CC   -!- SIMILARITY: Contains 1 KRAB domain.
CC   -!- SIMILARITY: Contains 1 SCAN box domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA76859.2; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000234619 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000196652;ENST00000451158;ENSP00000392104.
DR   EMBL; AB023232; - ;
DR   EMBL; AC005020; - ;
DR   EMBL; AF170025; - ;
DR   EMBL; AK027714; - ;
DR   EMBL; AK096552; - ;
DR   EMBL; BC030790; - ;
DR   EMBL; CH236956; - ;
DR   EMBL; CH471091; - ;
DR   UniProtKB/Swiss-Prot; Q9Y2L8; A4D280; D6W5S9; -.
DR   EMBL; AF170025; AAF24219.1; -; mRNA.
DR   EMBL; AB023232; BAA76859.2; ALT_INIT; mRNA.
DR   EMBL; CH236956; EAL23873.1; -; Genomic_DNA.
DR   EMBL; CH471091; EAW76654.1; -; Genomic_DNA.
DR   EMBL; CH471091; EAW76655.1; -; Genomic_DNA.
DR   EMBL; CH471091; EAW76656.1; -; Genomic_DNA.
DR   EMBL; CH471091; EAW76657.1; -; Genomic_DNA.
DR   IPI; IPI00032316; -.
DR   RefSeq; NP_055384.1; NM_014569.3.
DR   RefSeq; NP_659570.1; NM_145102.2.
DR   UniGene; Hs.110839; -.
DR   PDB; 2EM5; NMR; -; A=768-800.
DR   PDB; 2EMM; NMR; -; A=544-576.
DR   PDB; 2EMZ; NMR; -; A=628-660.
DR   PDB; 2EN3; NMR; -; A=796-828.
DR   PDB; 2EOM; NMR; -; A=341-373.
DR   PDB; 2EON; NMR; -; A=397-429.
DR   PDB; 2EOO; NMR; -; A=425-457.
DR   PDB; 2YSO; NMR; -; A=656-688.
DR   PDB; 2YTG; NMR; -; A=369-401.
DR   PDBsum; 2EM5; -.
DR   PDBsum; 2EMM; -.
DR   PDBsum; 2EMZ; -.
DR   PDBsum; 2EN3; -.
DR   PDBsum; 2EOM; -.
DR   PDBsum; 2EON; -.
DR   PDBsum; 2EOO; -.
DR   PDBsum; 2YSO; -.
DR   PDBsum; 2YTG; -.
DR   ProteinModelPortal; Q9Y2L8; -.
DR   SMR; Q9Y2L8; 44-133, 212-264, 342-829.
DR   IntAct; Q9Y2L8; 2.
DR   STRING; Q9Y2L8; -.
DR   PhosphoSite; Q9Y2L8; -.
DR   PRIDE; Q9Y2L8; -.
DR   Ensembl; ENST00000326775; ENSP00000322872; ENSG00000196652.
DR   Ensembl; ENST00000394170; ENSP00000377725; ENSG00000196652.
DR   Ensembl; ENST00000451158; ENSP00000392104; ENSG00000196652.
DR   GeneID; 23660; -.
DR   KEGG; hsa:23660; -.
DR   UCSC; uc003uqv.1; human.
DR   CTD; 23660; -.
DR   GeneCards; GC07P093738; -.
DR   HGNC; HGNC:12867; ZKSCAN5.
DR   HPA; HPA003201; -.
DR   MIM; 611272; gene.
DR   neXtProt; NX_Q9Y2L8; -.
DR   GeneTree; ENSGT00600000084347; -.
DR   InParanoid; Q9Y2L8; -.
DR   OMA; TNGERGH; -.
DR   OrthoDB; EOG45755X; -.
DR   PhylomeDB; Q9Y2L8; -.
DR   Reactome; REACT_71; Gene Expression.
DR   NextBio; 46509; -.
DR   ArrayExpress; Q9Y2L8; -.
DR   Bgee; Q9Y2L8; -.
DR   CleanEx; HS_ZKSCAN5; -.
DR   Genevestigator; Q9Y2L8; -.
DR   GermOnline; ENSG00000196652; Homo sapiens.
DR   GO; GO:0005634; C:nucleus; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral reproduction; IEA:InterPro.
DR   InterPro; IPR001909; Krueppel-associated_box.
DR   InterPro; IPR008916; Retrov_capsid_C.
DR   InterPro; IPR003309; Tscrpt_reg_SCAN.
DR   InterPro; IPR007087; Znf_C2H2.
DR   InterPro; IPR015880; Znf_C2H2-like.
DR   InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR   Gene3D; G3DSA:3.30.160.60; Znf_C2H2/integrase_DNA-bd; 13.
DR   Pfam; PF01352; KRAB; 1.
DR   Pfam; PF02023; SCAN; 1.
DR   Pfam; PF00096; zf-C2H2; 11.
DR   SMART; SM00349; KRAB; 1.
DR   SMART; SM00431; SCAN; 1.
DR   SMART; SM00355; ZnF_C2H2; 12.
DR   SUPFAM; SSF109640; Krueppel-associated_box; 1.
DR   SUPFAM; SSF47353; Retrov_capsid_C; 1.
DR   PROSITE; PS50805; KRAB; 1.
DR   PROSITE; PS50804; SCAN_BOX; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
DR   HOGENOMDNA; HS7.PE2584; -.
KW   ENSG000001966521755old_1320000031; ENSP000003921047901old_1320000031;
KW   B3KNK8_HUMAN; B3KU58_HUMAN; D6W5S9_HUMAN; Q75MV2_HUMAN; Q8N718_HUMAN;
KW   AC005020; AF170025; AK027714; AK096552; BC030790; CH236956; CH471091;
KW   3D-structure; Complete proteome; DNA-binding; Metal-binding; Nucleus;
KW   Phosphoprotein; Reference proteome; Repeat; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
SQ   SEQUENCE   839 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MIMTESREVI DLDPPAETSQ EQEDLFIVKV EEEDCTWMQE YNPPTFETFY QRFRHFQYHE
     ASGPREALSQ LRVLCCEWLR PELHTKEQIL ELLVLEQFLT ILPEEFQPWV REHHPESGEE
     AVAVIENIQR ELEERRQQIV ACPDVLPRKM ATPGAVQESC SPHPLTVDTQ PEQAPQKPRL
     LEENALPVLQ VPSLPLKDSQ ELTASLLSTG SQKLVKIEEV ADVAVSFILE EWGHLDQSQK
     SLYRDDRKEN YGSITSMGYE SRDNMELIVK QISDDSESHW VAPEHTERSV PQDPDFAEVS
     DLKGMVQRWQ VNPTVGKSRQ NPSQKRDLDA ITDISPKQST HGERGHRCSD CGKFFLQASN
     FIQHRRIHTG EKPFKCGECG KSYNQRVHLT QHQRVHTGEK PYKCQVCGKA FRVSSHLVQH
     HSVHSGERPY GCNECGKNFG RHSHLIEHLK RHFREKSQRC SDKRSKNTKL SVKKKISEYS
     EADMELSGKT QRNVSQVQDF GEGCEFQGKL DRKQGIPMKE ILGQPSSKRM NYSEVPYVHK
     KSSTGERPHK CNECGKSFIQ SAHLIQHQRI HTGEKPFRCE ECGKSYNQRV HLTQHQRVHT
     GEKPYTCPLC GKAFRVRSHL VQHQSVHSGE RPFKCNECGK GFGRRSHLAG HLRLHSREKS
     HQCRECGEIF FQYVSLIEHQ VLHMGQKNEK NGICEEAYSW NLTVIEDKKI ELQEQPYQCD
     ICGKAFGYSS DLIQHYRTHT AEKPYQCDIC RENVGQCSHT KQHQKIYSST KSHQCHECGR
     GFTLKSHLNQ HQRIHTGEKP FQCKECGMNF SWSCSLFKHL RSHERTDPIN TLSVEGSLL
//

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