(data stored in ACNUC24361 zone)

HOGENOM: HS7_PE2650

ID   HS7_PE2650                           STANDARD;      PRT;   563 AA.
AC   HS7_PE2650; P17029; A4D294; P52745; Q2M1U1; Q8TBW5; Q8TEK7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;AltName:
DE   Full=Zinc finger protein 139;AltName: Full=Zinc finger protein
DE   36;AltName: Full=Zinc finger protein KOX18; (HS7.PE2650).
GN   Name=ZKSCAN1; Synonyms=KOX18, ZNF139, ZNF36;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS7.PE2650.
CC       Homo sapiens chromosome 7 GRCh37  sequence 1..159128663 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ZKSC1_HUMAN
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus (Potential).
CC   -!- PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family.
CC   -!- SIMILARITY: Contains 6 C2H2-type zinc fingers.
CC   -!- SIMILARITY: Contains 1 KRAB domain.
CC   -!- SIMILARITY: Contains 1 SCAN box domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC50264.1; Type=Frameshift; Positions=241;
CC   -!- GENE_FAMILY: HOG000234619 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000106261;ENST00000324306;ENSP00000323148.
DR   EMBL; AC004522; - ;
DR   EMBL; AC093619; - ;
DR   EMBL; AF454940; - ;
DR   EMBL; AK054676; - ;
DR   EMBL; AK074116; - ;
DR   EMBL; AK091471; - ;
DR   EMBL; AK123012; - ;
DR   EMBL; BC022378; - ;
DR   EMBL; BC112224; - ;
DR   EMBL; BC113697; - ;
DR   EMBL; BX640646; - ;
DR   EMBL; CH236956; - ;
DR   EMBL; CH471091; - ;
DR   EMBL; U09848; - ;
DR   EMBL; X52349; - ;
DR   UniProtKB/Swiss-Prot; P17029; A4D294; P52745; Q2M1U1; Q8TBW5; Q8TEK7; -.
DR   EMBL; AK074116; BAB84942.1; -; mRNA.
DR   EMBL; BX640646; CAE45792.1; -; mRNA.
DR   EMBL; CH236956; EAL23861.1; -; Genomic_DNA.
DR   EMBL; CH471091; EAW76613.1; -; Genomic_DNA.
DR   EMBL; BC022378; AAH22378.1; -; mRNA.
DR   EMBL; BC112224; AAI12225.1; -; mRNA.
DR   EMBL; BC113697; AAI13698.1; -; mRNA.
DR   EMBL; U09848; AAC50264.1; ALT_FRAME; mRNA.
DR   EMBL; X52349; CAA36575.1; -; mRNA.
DR   IPI; IPI00657757; -.
DR   PIR; I38616; I38616.
DR   RefSeq; NP_003430.1; NM_003439.1.
DR   UniGene; Hs.615360; -.
DR   ProteinModelPortal; P17029; -.
DR   SMR; P17029; 50-138, 293-539.
DR   STRING; P17029; -.
DR   PhosphoSite; P17029; -.
DR   PRIDE; P17029; -.
DR   Ensembl; ENST00000324306; ENSP00000323148; ENSG00000106261.
DR   GeneID; 7586; -.
DR   KEGG; hsa:7586; -.
DR   UCSC; uc003usk.1; human.
DR   CTD; 7586; -.
DR   GeneCards; GC07P094248; -.
DR   HGNC; HGNC:13101; ZKSCAN1.
DR   HPA; HPA006672; -.
DR   MIM; 601260; gene.
DR   neXtProt; NX_P17029; -.
DR   PharmGKB; PA37676; -.
DR   InParanoid; P17029; -.
DR   OMA; KREQQGR; -.
DR   OrthoDB; EOG4DJJW3; -.
DR   PhylomeDB; P17029; -.
DR   Reactome; REACT_71; Gene Expression.
DR   NextBio; 29653; -.
DR   ArrayExpress; P17029; -.
DR   Bgee; P17029; -.
DR   CleanEx; HS_ZKSCAN1; -.
DR   Genevestigator; P17029; -.
DR   GermOnline; ENSG00000106261; Homo sapiens.
DR   GO; GO:0005739; C:mitochondrion; IDA:HPA.
DR   GO; GO:0005634; C:nucleus; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral reproduction; IEA:InterPro.
DR   InterPro; IPR001909; Krueppel-associated_box.
DR   InterPro; IPR008916; Retrov_capsid_C.
DR   InterPro; IPR003309; Tscrpt_reg_SCAN.
DR   InterPro; IPR007087; Znf_C2H2.
DR   InterPro; IPR015880; Znf_C2H2-like.
DR   InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR   Gene3D; G3DSA:3.30.160.60; Znf_C2H2/integrase_DNA-bd; 6.
DR   Pfam; PF01352; KRAB; 1.
DR   Pfam; PF02023; SCAN; 1.
DR   Pfam; PF00096; zf-C2H2; 6.
DR   SMART; SM00349; KRAB; 1.
DR   SMART; SM00431; SCAN; 1.
DR   SMART; SM00355; ZnF_C2H2; 6.
DR   SUPFAM; SSF109640; Krueppel-associated_box; 1.
DR   SUPFAM; SSF47353; Retrov_capsid_C; 1.
DR   PROSITE; PS50805; KRAB; 1.
DR   PROSITE; PS50804; SCAN_BOX; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
DR   HOGENOMDNA; HS7.PE2650; -.
KW   ENSG000001062611755old_1320000031; ENSP000003231487901old_1320000031;
KW   B3KNP9_HUMAN; B3KRF7_HUMAN; B3KVN6_HUMAN; C9JRM9_HUMAN; Q7Z4R1_HUMAN;
KW   AC093619; AF454940; AK054676; AK074116; AK091471; AK123012; BC022378;
KW   BC113697; BX640646; CH236956; CH471091; U09848; X52349;
KW   Complete proteome; DNA-binding; Metal-binding; Nucleus;
KW   Phosphoprotein; Polymorphism; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
SQ   SEQUENCE   563 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MMTAESREAT GLSPQAAQEK DGIVIVKVEE EDEEDHMWGQ DSTLQDTPPP DPEIFRQRFR
     RFCYQNTFGP REALSRLKEL CHQWLRPEIN TKEQILELLV LEQFLSILPK ELQVWLQEYR
     PDSGEEAVTL LEDLELDLSG QQVPGQVHGP EMLARGMVPL DPVQESSSFD LHHEATQSHF
     KHSSRKPRLL QSRALPAAHI PAPPHEGSPR DQAMASALFT ADSQAMVKIE DMAVSLILEE
     WGCQNLARRN LSRDNRQENY GSAFPQGGEN RNENEESTSK AETSEDSASR GETTGRSQKE
     FGEKRDQEGK TGERQQKNPE EKTRKEKRDS GPAIGKDKKT ITGERGPREK GKGLGRSFSL
     SSNFTTPEEV PTGTKSHRCD ECGKCFTRSS SLIRHKIIHT GEKPYECSEC GKAFSLNSNL
     VLHQRIHTGE KPHECNECGK AFSHSSNLIL HQRIHSGEKP YECNECGKAF SQSSDLTKHQ
     RIHTGEKPYE CSECGKAFNR NSYLILHRRI HTREKPYKCT KCGKAFTRSS TLTLHHRIHA
     RERASEYSPA SLDAFGAFLK SCV
//

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