(data stored in ACNUC30567 zone)

HOGENOM: HS8_PE1190

ID   HS8_PE1190                           STANDARD;      PRT;   629 AA.
AC   HS8_PE1190; Q2VYF6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Metalloproteinase 12-like protein; (HS8.PE1190).
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS8.PE1190.
CC       Homo sapiens chromosome 8 GRCh37  sequence 1..146304022 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q2VYF6_HUMAN
CC   -!- SIMILARITY: Contains 1 disintegrin domain.
CC   -!- SIMILARITY: Contains 1 peptidase M12B domain.
CC   -!- GENE_FAMILY: HOG000230883 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000197140;ENST00000519315;ENSP00000429422.
DR   EMBL; AK122608; - ;
DR   EMBL; AY172952; - ;
DR   UniProtKB/Swiss-Prot; Q2VYF6; -.
DR   EMBL; AY172952; AAO45696.1; -; mRNA.
DR   IPI; IPI00985092; -.
DR   UniGene; Hs.521545; -.
DR   ProteinModelPortal; Q2VYF6; -.
DR   PRIDE; Q2VYF6; -.
DR   UCSC; uc003xmu.2; human.
DR   HGNC; HGNC:15479; ADAM32.
DR   ArrayExpress; Q2VYF6; -.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR006586; ADAM_Cys-rich.
DR   InterPro; IPR001762; Blood-coag_inhib_Disintegrin.
DR   InterPro; IPR018358; Disintegrin_CS.
DR   InterPro; IPR006210; EGF-like.
DR   InterPro; IPR013032; EGF-like_reg_CS.
DR   InterPro; IPR000742; EGF_3.
DR   InterPro; IPR024079; MetalloPept_cat_dom.
DR   InterPro; IPR001590; Peptidase_M12B.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   Gene3D; G3DSA:4.10.70.10; Blood-coag_inhib_Disintegrin; 1.
DR   Gene3D; G3DSA:3.40.390.10; G3DSA:3.40.390.10; 1.
DR   Pfam; PF08516; ADAM_CR; 1.
DR   Pfam; PF00200; Disintegrin; 1.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
DR   Pfam; PF01421; Reprolysin; 1.
DR   SMART; SM00608; ACR; 1.
DR   SMART; SM00050; DISIN; 1.
DR   SMART; SM00181; EGF; 1.
DR   SUPFAM; SSF57552; Disintegrin; 1.
DR   PROSITE; PS50215; ADAM_MEPRO; 1.
DR   PROSITE; PS00427; DISINTEGRIN_1; 1.
DR   PROSITE; PS50214; DISINTEGRIN_2; 1.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 1.
DR   HOGENOMDNA; HS8.PE1190; -.
KW   ENSG000001971401755old_1320000031; ENSP000004294227901old_1320000031;
KW   Q6ZWL1_HUMAN; AK122608; AY172952.
SQ   SEQUENCE   629 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MFRLWLLLAG LCGLLASRPG FQNSLLQIVI PEKIQTNTND SSEIEYEQIS YIIPIDEKLY
     TVHLKQRYFL ADNFMIYLYN QGSMNTYSSD IQTQCYYQGN IEGYPDSMVT LSTCSGLRGI
     LQFENVSYGI EPLESAVEFQ HVLYKLKNED NDIAIFIDRS LKEQPMDDNI FISEKSEPAV
     PDLFPLYLEM HIVVDKTLYD YWGSDSMIVT NKVIEIVGLA NSMFTQFKVT IVLSSLELWS
     DENKISTVGE ADELLQKFLE WKQSYLNLRP HDIAYLLIYM DYPRYLGAVF PGTMCITRYS
     AGVALQCGPA SCCDFRTCVL KDGAKCYKGL CCKDCQILQS GVECRPKAHP ECDIAENCNG
     TSPECGPDIT LINGLSCKNN KFICYDGDCH DLDARCESVF GKGSRNAPFA CYEEIQSQSD
     RFGNCGRDRN NKYVFCGWRN LICGRLVCTY PTRKPFHQEN GDVIYAFVRD SVCITVDYKL
     PRTVPDPLAV KNGSQCDIGR VCVNRECVES RIIKASAHVC SQQCSGHGVC DSRNKCHCSP
     GYKPPNCQIR SKGFSIFPEE DMGSIMERAS GKTENTWLLG FLIALPILIV TTAIVLARKQ
     LKKWFAKEEE FPSSESKSQD STQTQSSSN
//

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