(data stored in ACNUC26462 zone)

HOGENOM: HS8_PE2120

ID   HS8_PE2120                           STANDARD;      PRT;   385 AA.
AC   HS8_PE2120; Q96QS6; A0AV22;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Serine/threonine-protein kinase H2; EC=2.7.11 1;AltName:
DE   Full=Protein serine kinase H2; Short=PSK-H2; (HS8.PE2120).
GN   Name=PSKH2;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS8.PE2120.
CC       Homo sapiens chromosome 8 GRCh37  sequence 1..146304022 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:KPSH2_HUMAN
CC   -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK
CC       Ser/Thr protein kinase family.
CC   -!- SIMILARITY: Contains 1 protein kinase domain.
CC   -!- CAUTION: Asn-183 is present instead of the conserved Asp which is
CC       expected to be an active site residue.
CC   -!- GENE_FAMILY: HOG000233016 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000147613;ENST00000276616;ENSP00000276616.
DR   EMBL; AY037806; - ;
DR   EMBL; BC126180; - ;
DR   EMBL; BC126182; - ;
DR   UniProtKB/Swiss-Prot; Q96QS6; A0AV22; -.
DR   EMBL; AY037806; AAK59985.1; -; mRNA.
DR   EMBL; BC126180; AAI26181.1; -; mRNA.
DR   EMBL; BC126182; AAI26183.1; -; mRNA.
DR   IPI; IPI00045068; -.
DR   RefSeq; NP_149117.1; NM_033126.1.
DR   UniGene; Hs.680136; -.
DR   ProteinModelPortal; Q96QS6; -.
DR   SMR; Q96QS6; 58-323.
DR   PhosphoSite; Q96QS6; -.
DR   PRIDE; Q96QS6; -.
DR   Ensembl; ENST00000276616; ENSP00000276616; ENSG00000147613.
DR   GeneID; 85481; -.
DR   KEGG; hsa:85481; -.
DR   UCSC; uc003ydo.1; human.
DR   CTD; 85481; -.
DR   GeneCards; GC08M082270; -.
DR   H-InvDB; HIX0034313; -.
DR   HGNC; HGNC:18997; PSKH2.
DR   HPA; HPA015095; -.
DR   neXtProt; NX_Q96QS6; -.
DR   PharmGKB; PA134961168; -.
DR   eggNOG; prNOG06076; -.
DR   GeneTree; ENSGT00550000074354; -.
DR   InParanoid; Q96QS6; -.
DR   OMA; REACVSE; -.
DR   OrthoDB; EOG4DFPNV; -.
DR   PhylomeDB; Q96QS6; -.
DR   NextBio; 76154; -.
DR   ArrayExpress; Q96QS6; -.
DR   Bgee; Q96QS6; -.
DR   CleanEx; HS_PSKH2; -.
DR   Genevestigator; Q96QS6; -.
DR   GermOnline; ENSG00000147613; Homo sapiens.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR020636; Ca/CaM-dep_Ca-dep_prot_Kinase.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR017442; Se/Thr_kinase-like_dom.
DR   InterPro; IPR002290; Ser/Thr_kinase_dom.
DR   PANTHER; PTHR24347; PTHR24347; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; FALSE_NEG.
DR   HOGENOMDNA; HS8.PE2120; -.
KW   ENSG000001476131755old_1320000031; ENSP000002766167901old_1320000031;
KW   AY037806; BC126180; BC126182;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW   Polymorphism; Reference proteome; Serine/threonine-protein kinase;
KW   Transferase.
SQ   SEQUENCE   385 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGCGASRKVV PGPPALAWAK HEGQNQAGVG GAGPGPEAAA QAAQRIQVAR FRAKFDPRVL
     ARYDIKALIG TGSFSRVVRV EQKTTKKPFA IKVMETRERE GREACVSELS VLRRVSHRYI
     VQLMEIFETE DQVYMVMELA TGGELFDRLI AQGSFTERDA VRILQMVADG IRYLHALQIT
     HRNLKPENLL YYHPGEESKI LITDFGLAYS GKKSGDWTMK TLCGTPEYIA PEVLLRKPYT
     SAVDMWALGV ITYALLSGFL PFDDESQTRL YRKILKGKYN YTGEPWPSIS HLAKDFIDKL
     LILEAGHRMS AGQALDHPWV ITMAAGSSMK NLQRAISRNL MQRASPHSQS PGSAQSSKSH
     YSHKSRHMWS KRNLRIVESP LSALL
//

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