(data stored in ACNUC30567 zone)

HOGENOM: HS8_PE687

ID   HS8_PE687                            STANDARD;      PRT;   540 AA.
AC   HS8_PE687; B4DDY3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Uncharacterized protein;SubName: Full=cDNA FLJ60418, highly
DE   similar to ADAM 28 (HS8.PE687) (EC 3.4.24 -) (Adisintegrin and
DE   metalloproteinase domain 28); .
GN   Name=ADAM28;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS8.PE687.
CC       Homo sapiens chromosome 8 GRCh37  sequence 1..146304022 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:B4DDY3_HUMAN
CC   -!- SIMILARITY: Contains 1 disintegrin domain.
CC   -!- SIMILARITY: Contains 1 peptidase M12B domain.
CC   -!- GENE_FAMILY: HOG000230883 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000042980;ENST00000437154;ENSP00000393699.
DR   EMBL; AK293382; - ;
DR   UniProtKB/Swiss-Prot; B4DDY3; -.
DR   EMBL; AC044891; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC120193; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK293382; BAG56894.1; -; mRNA.
DR   IPI; IPI01010046; -.
DR   UniGene; Hs.174030; -.
DR   STRING; B4DDY3; -.
DR   Ensembl; ENST00000540823; ENSP00000443743; ENSG00000042980.
DR   HGNC; HGNC:206; ADAM28.
DR   GeneTree; ENSGT00590000082827; -.
DR   Bgee; B4DDY3; -.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR006586; ADAM_Cys-rich.
DR   InterPro; IPR001762; Blood-coag_inhib_Disintegrin.
DR   InterPro; IPR018358; Disintegrin_CS.
DR   InterPro; IPR024079; MetalloPept_cat_dom.
DR   InterPro; IPR001590; Peptidase_M12B.
DR   Gene3D; G3DSA:4.10.70.10; Blood-coag_inhib_Disintegrin; 1.
DR   Gene3D; G3DSA:3.40.390.10; G3DSA:3.40.390.10; 1.
DR   Pfam; PF08516; ADAM_CR; 1.
DR   Pfam; PF00200; Disintegrin; 1.
DR   Pfam; PF01421; Reprolysin; 1.
DR   PRINTS; PR00289; DISINTEGRIN.
DR   SMART; SM00050; DISIN; 1.
DR   SUPFAM; SSF57552; Disintegrin; 1.
DR   PROSITE; PS50215; ADAM_MEPRO; 1.
DR   PROSITE; PS00427; DISINTEGRIN_1; 1.
DR   PROSITE; PS50214; DISINTEGRIN_2; 1.
DR   HOGENOMDNA; HS8.PE687; -.
KW   ENSG000000429801755old_1320000031; ENSP000003936997901old_1320000031;
KW   AK293382;
KW   Complete proteome; Integrin; Reference proteome.
SQ   SEQUENCE   540 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLQGLLPVSL LLSVAVSAIK ELPGVKKYEV VYPIRLHPLH KREAKEPEQQ EQFETELKYK
     MTINGKIAVL YLKKNKNLLA PGYTETYYNS TGKEITTSPQ IMDDCYYQGH ILNEKVSDAS
     ISTCRGLRGY FSQGDQRYFI EPLSPIHRDG QEHALFKYNP DEKNYDSTCG MDGVLWAHDL
     QQNIALPATK LVKLKDRKVQ EHEKYIEYYL VLDNGEFKRY NENQDEIRKR VFEMANYVNM
     LYKKLNTHVA LVGMEIWTDK DKIKITPNAS FTLENFSKWR GSVLSRRKRH DIAQLITATE
     LAGTTVGLAF MSTMCSPYSV GVVQDHSDNL LRVAGTMAHE MGHNFGMFHD DYSCKCPSTI
     CVMDKALSFY IPTDFSSCSR LSYDKFFEDK LSNCLFNAPL PTDIISTPIC GNQLVEMGED
     CDCGTSEECT NICCDAKTCK IKATFQCALG ECCEKCQFKK AGMVCRPAKD ECDLPEMCNG
     KSGNCPDDRF QVNGFPCHHG KGHCLMGTCP TLQEQCTELW GPGRRTNPFP CACAKENHFR
//

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