(data stored in ACNUC30567 zone)

HOGENOM: HS8_PE692

ID   HS8_PE692                            STANDARD;      PRT;   391 AA.
AC   HS8_PE692; B7Z6V5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=cDNA FLJ50240, highly similar to ADAM DEC1 (HS8.PE692) (EC
DE   3.4.24 -) (Adisintegrin and metalloproteinase domain-like protein decysin
DE   1); .
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HS8.PE692.
CC       Homo sapiens chromosome 8 GRCh37  sequence 1..146304022 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:B7Z6V5_HUMAN
CC   -!- SIMILARITY: Contains 1 disintegrin domain.
CC   -!- SIMILARITY: Contains 1 peptidase M12B domain.
CC   -!- GENE_FAMILY: HOG000230883 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000134028;ENST00000522298;ENSP00000428993.
DR   EMBL; AK300959; - ;
DR   EMBL; AK301007; - ;
DR   EMBL; AK316320; - ;
DR   EMBL; AK316322; - ;
DR   UniProtKB/Swiss-Prot; B7Z6V5; -.
DR   EMBL; AK301007; BAH13391.1; -; mRNA.
DR   IPI; IPI00004480; -.
DR   RefSeq; NP_001138743.1; NM_001145271.1.
DR   RefSeq; NP_001138744.1; NM_001145272.1.
DR   RefSeq; NP_055294.1; NM_014479.3.
DR   UniGene; Hs.521459; -.
DR   STRING; B7Z6V5; -.
DR   GeneID; 27299; -.
DR   KEGG; hsa:27299; -.
DR   CTD; 27299; -.
DR   HGNC; HGNC:16299; ADAMDEC1.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR001762; Blood-coag_inhib_Disintegrin.
DR   InterPro; IPR024079; MetalloPept_cat_dom.
DR   InterPro; IPR001590; Peptidase_M12B.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   Gene3D; G3DSA:3.40.390.10; G3DSA:3.40.390.10; 1.
DR   Pfam; PF00200; Disintegrin; 1.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
DR   Pfam; PF01421; Reprolysin; 1.
DR   PROSITE; PS50215; ADAM_MEPRO; 1.
DR   PROSITE; PS50214; DISINTEGRIN_2; 1.
DR   HOGENOMDNA; HS8.PE692; -.
KW   ENSG000001340281755old_1320000031; ENSP000004289937901old_1320000031;
KW   B7Z6V5_HUMAN; B7ZAK5_HUMAN; AK300959; AK301007; AK316320; AK316322;
KW   Hydrolase; Integrin; Metal-binding; Metalloprotease; Protease.
SQ   SEQUENCE   391 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MILNGEEIIL SLQKTKHLLG PDYTETLYSP RGEEITTKPE NMEHCYYKGN ILNEKNSVAS
     ISTCDGLRGY FTHHHQRYQI KPLKSTDEKE HAVFTSNQEE QDPANHTCGV KSTDGKQGPI
     RISRSLKSPE KEDFLRAQKY IDLYLVLDNA FYKNYNENLT LIRSFVFDVM NLLNVIYNTI
     DVQVALVGME IWSDGDKIKV VPSASTTFDN FLRWHSSNLG KKIHDHAQLL SGISFNNRRV
     GLAASNSLCS PSSVAVIEAK KKNNVALVGV MSHELGHVLG MPDVPFNTKC PSGSCVMNQY
     LSSKFPKDFS TSCRAHFERY LLSQKPKCLL QAPIPTNIMT TPVCGNHLLE VGEDCDCGSP
     KECTNLCCEA LTCKLKPGTD CGGDAPNHTT E
//

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