(data stored in ACNUC15465 zone)

HOGENOM: HSX_PE973

ID   HSX_PE973                            STANDARD;      PRT;   117 AA.
AC   HSX_PE973; Q13067;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=G antigen 3; Short=GAGE-3;AltName: Full=Cancer/testis
DE   antigen 4.3; Short=CT4 3; (HSX.PE973).
GN   Name=GAGE3;
OS   HOMO SAPIENS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Homo.
OX   NCBI_TaxID=9606;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS HSX.PE973.
CC       Homo sapiens chromosome X GRCh37  sequence 1..155260560 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:GAGE3_HUMAN
CC   -!- TISSUE SPECIFICITY: Expressed in a variety of tumor tissues but
CC       not in normal tissues, except testis.
CC   -!- MISCELLANEOUS: This gene belongs to a family of genes organized in
CC       clustered repeats. They have a high degree of predicted sequence
CC       identity, but differ by scattered single nucleotide substitution.
CC       Their sequences contain either the antigenic peptide YYWPRPRRY or
CC       YRPRPRRY which is recognized by cytotoxic T cells.
CC   -!- SIMILARITY: Belongs to the GAGE family.
CC   -!- CAUTION: The first GAGE nomenclature was based on identified mRNA
CC       sequences, but the high identity of the GAGE members made
CC       impossible to separate products of paralogous genes from polymorph
CC       products. PubMed:18179644 presented a new GAGE gene nomenclature
CC       based on the identified genes and their products.
CC   -!- GENE_FAMILY: HOG000237345 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Homo_sapiens;ENSG00000205777;ENST00000451387;ENSP00000406557.
DR   EMBL; AC142497; - ;
DR   EMBL; BC024914; - ;
DR   EMBL; BC069470; - ;
DR   EMBL; BC081536; - ;
DR   EMBL; BC171769; - ;
DR   EMBL; CR542236; - ;
DR   EMBL; U19144; - ;
DR   EMBL; U19145; - ;
DR   EMBL; U19146; - ;
DR   EMBL; U19147; - ;
DR   UniProtKB/Swiss-Prot; Q13067; -.
DR   EMBL; U19144; AAA82746.1; -; mRNA.
DR   IPI; IPI00011529; -.
DR   STRING; Q13067; -.
DR   PhosphoSite; Q13067; -.
DR   Ensembl; ENST00000404804; ENSP00000384542; ENSG00000215269.
DR   Ensembl; ENST00000415752; ENSP00000391465; ENSG00000241465.
DR   Ensembl; ENST00000422672; ENSP00000405110; ENSG00000241465.
DR   Ensembl; ENST00000440137; ENSP00000404123; ENSG00000236362.
DR   Ensembl; ENST00000445148; ENSP00000416249; ENSG00000215269.
DR   Ensembl; ENST00000447358; ENSP00000399049; ENSG00000236362.
DR   Ensembl; ENST00000451387; ENSP00000406557; ENSG00000205777.
DR   GeneCards; GC0XP049355; -.
DR   HGNC; HGNC:4100; GAGE3.
DR   MIM; 300596; gene.
DR   neXtProt; NX_Q13067; -.
DR   InParanoid; Q13067; -.
DR   OrthoDB; EOG4C5CM1; -.
DR   ArrayExpress; Q13067; -.
DR   Bgee; Q13067; -.
DR   Genevestigator; Q13067; -.
DR   GermOnline; ENSG00000068990; Homo sapiens.
DR   GermOnline; ENSG00000198716; Homo sapiens.
DR   GermOnline; ENSG00000205777; Homo sapiens.
DR   InterPro; IPR008625; GAGE.
DR   Pfam; PF05831; GAGE; 1.
DR   HOGENOMDNA; HSX.PE973; -.
KW   ENSG000002057771755old_1320000031; ENSP000004065577901old_1320000031;
KW   GAGE4_HUMAN; GAGE5_HUMAN; GAGE6_HUMAN; GG12F_HUMAN; B5MC01_HUMAN;
KW   AC142497; BC024914; BC069470; BC081536; BC171769; CR542236; U19144;
KW   U19146; U19147;
KW   Complete proteome; Phosphoprotein; Reference proteome.
SQ   SEQUENCE   117 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSWRGRSTYY WPRPRRYVQP PEMIGPMRPE QFSDEVEPAT PEEGEPATQR QDPAAAQEGE
     DEGASAGQGP KPEADSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE GEGQSQC
//

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