(data stored in ACNUC7421 zone)

HOGENOM: IDLOI1_1_PE1006

ID   IDLOI1_1_PE1006                      STANDARD;      PRT;   872 AA.
AC   IDLOI1_1_PE1006; Q5QWH4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase; EC=5.99.1 2; (IDLOI1_1.PE1006).
GN   Name=topA; OrderedLocusNames=IL1010;
OS   IDIOMARINA LOIHIENSIS L2TR.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Idiomarinaceae; Idiomarina.
OX   NCBI_TaxID=283942;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS IDLOI1_1.PE1006.
CC       Idiomarina loihiensis L2TR chromosome, complete genome.
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q5QWH4_IDILO
CC   -!- FUNCTION: The reaction catalyzed by topoisomerases leads to the
CC       conversion of one topological isomer of DNA to another (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-independent breakage of single-stranded
CC       DNA, followed by passage and rejoining.
CC   -!- SIMILARITY: Belongs to the prokaryotic type I/III topoisomerase
CC       family.
CC   -!- SIMILARITY: Contains 1 Toprim domain.
CC   -!- GENE_FAMILY: HOG000004018 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5QWH4; -.
DR   EMBL; AE017340; AAV81850.1; -; Genomic_DNA.
DR   RefSeq; YP_155399.1; NC_006512.1.
DR   ProteinModelPortal; Q5QWH4; -.
DR   SMR; Q5QWH4; 2-602, 752-867.
DR   GeneID; 3172060; -.
DR   GenomeReviews; AE017340_GR; IL1010.
DR   KEGG; ilo:IL1010; -.
DR   NMPDR; fig|283942.3.peg.369; -.
DR   OMA; EEYWSID; -.
DR   ProtClustDB; PRK07561; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR000380; Topo_IA.
DR   InterPro; IPR003601; Topo_IA_2.
DR   InterPro; IPR023406; Topo_IA_AS.
DR   InterPro; IPR013497; Topo_IA_cen.
DR   InterPro; IPR013824; Topo_IA_cen_sub1.
DR   InterPro; IPR013825; Topo_IA_cen_sub2.
DR   InterPro; IPR023405; Topo_IA_core_domain.
DR   InterPro; IPR003602; Topo_IA_DNA-bd.
DR   InterPro; IPR013498; Topo_IA_Znf.
DR   InterPro; IPR005733; TopoI_bac-type.
DR   InterPro; IPR013263; TopoI_Znr_bac.
DR   InterPro; IPR006171; Toprim_domain.
DR   Gene3D; G3DSA:1.10.460.10; Topo_IA_cen_sub1; 2.
DR   Gene3D; G3DSA:2.70.20.10; Topo_IA_cen_sub2; 2.
DR   PANTHER; PTHR11390; Topo_IA; 1.
DR   Pfam; PF08272; Topo_Zn_Ribbon; 2.
DR   Pfam; PF01131; Topoisom_bac; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   Pfam; PF01396; zf-C4_Topoisom; 2.
DR   PRINTS; PR00417; PRTPISMRASEI.
DR   SMART; SM00437; TOP1Ac; 1.
DR   SMART; SM00436; TOP1Bc; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   SUPFAM; SSF56712; Topo_IA_core; 1.
DR   TIGRFAMs; TIGR01051; TopA_bact; 1.
DR   PROSITE; PS00396; TOPOISOMERASE_I_PROK; 1.
DR   HOGENOMDNA; IDLOI1_1.PE1006; -.
KW   ATP-binding; Complete proteome; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   872 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAKSLVIVES PAKAKTINKY LGKDFVVKSS VGHVRDLPTR ATETIKSKPA AEVRKMSPDA
     KAKYQKERDY KRLIARMGVD PENDWEAHYE VLQGKEKVVK ELKQLAKKSD EIILATDLDR
     EGEAIAWHLR ELIGGDDSRY KRVVFNEITK KAIQEAFQHP AELNTDRVNA QQTRRFLDRV
     VGFMVSPLLW KKIARGLSAG RVQSVAVRLV VEREREIKAF VPEEYWDVHA DLNTPADESL
     RMQVMKQAGK NFRPSNKQET DAALALLKKA GYEITGREDK PTSSKPSAPF ITSTLQQAAS
     TRLGFGVKKT MMMAQRLYEA GHITYMRTDS TNLSSEAVDA CRELITKDFG KNYLPDDPVR
     YGAKSNAQEA HEAIRPSDVK VKSESLASVE RDAQRLYELI WRQFVACQMV PARYDSTTLT
     ATAGDFELKA RGRVMRFAGW TKVMPPASSK KDGDATLPDV KKGDALQLEK LNPEQHFTKP
     PARYGEASLV KELEKRGIGR PSTYASIIST IQDRGYVRVE SRRFFAEKMG EIVNDRLIEN
     FTELMNYNFT AEMEQALDDI AAGKRDWKET LDKFYADFKE RLEKAELEPT EGGMRENSMV
     LTDIDCPECG RKMGIRTAST GVFLGCSGYN LPPKERCTKT LNLTPGEEAI EVTDEEERET
     EALRAKKRCP KCGTAMDSYL IDEKRKLHVC GNNPTCDGQL VEEGTFRIKG YDGPTIECDK
     CGSEMQLKTG RFGKYFGCTN SECKNTRKLL RSGEAAPPKE DPVPLPELPC EESDAYFVLR
     DGASGIFLSA NTFPKSRETR AVTVKELAKF KDRLPEKFKY LAEAPKEDDD GNDAIVRFSR
     KNKEQYVVTE IKKKQTGWKA FYRSGKWQVE EK
//

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