(data stored in ACNUC10043 zone)

HOGENOM: IGNAA_1_PE1001

ID   IGNAA_1_PE1001                       STANDARD;      PRT;   430 AA.
AC   IGNAA_1_PE1001; E0SNQ8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=tRNA pseudouridine synthase Pus10; EC=5.4.99 -;AltName:
DE   Full=tRNA pseudouridine 54/55 synthase; Short=Psi54/55 synthase;
DE   (IGNAA_1.PE1001).
GN   Name=pus10; OrderedLocusNames=Igag_1040;
OS   IGNISPHAERA AGGREGANS DSM 17230.
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Ignisphaera.
OX   NCBI_TaxID=583356;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS IGNAA_1.PE1001.
CC       Ignisphaera aggregans DSM 17230 chromosome, complete genome.
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:PUS10_IGNAA
CC   -!- FUNCTION: Responsible for synthesis of pseudouridine from uracil-
CC       54 and uracil-55 in the psi GC loop of transfer RNAs (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: tRNA uridine = tRNA pseudouridine.
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase Pus10 family.
CC   -!- GENE_FAMILY: HOG000227928 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E0SNQ8; -.
DR   EMBL; CP002098; ADM27854.1; -; Genomic_DNA.
DR   RefSeq; YP_003859734.1; NC_014471.1.
DR   GeneID; 9716356; -.
DR   GenomeReviews; CP002098_GR; Igag_1040.
DR   KEGG; iag:Igag_1040; -.
DR   OMA; PQTRWPC; -.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   HAMAP; MF_01893; Pus10_arch; 1; -.
DR   InterPro; IPR005912; CHP01213.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom.
DR   InterPro; IPR004114; THUMP.
DR   Pfam; PF02926; THUMP; 1.
DR   SUPFAM; SSF55120; PsdUridine_synth_cat_dom; 1.
DR   TIGRFAMs; TIGR01213; TIGR01213; 1.
DR   PROSITE; PS51165; THUMP; FALSE_NEG.
DR   HOGENOMDNA; IGNAA_1.PE1001; -.
KW   pseudouridylate synthase;
KW   Complete proteome; Isomerase; RNA-binding; tRNA processing.
SQ   SEQUENCE   430 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSIIDIANNI LRKYCLCDRC LGRLFASLGR GLSNDERGKA IKIALVLELH KRYLDGDKDS
     LKQLVELSPN IGPIAVNLIK NLGIEIEYTP RTCFICDNKI NDIIDTYSQR IADIINERHI
     NSFVLGIRGV TSYIRKEESI ANEFKLLYWE NIKRELKREI GKKIQMMTNA KVDFLNPEAM
     IIIDIDRDRI YIESPSLLIY GRYWKLGRMI SQNIWLTKNG VKKYPLSIEE IAKMLVKDGF
     GDDVVLHIAG REDVDVRTLG SGRPFVLEIK RPRKRNIDIK DIENRLNSIS RWLKFELNMF
     VDRDFVSRVK KGCRTSYKIY RAIVVADRDI GIEDIKRLEE FFRDRIIEQR TPTRVLRRKK
     DVLRRRKVFE IKTRVISPRV FEALIKCEGG LYVKELISGD NGRTVPSFSS VLNANTLCLT
     LDALYVHEYI
//

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