(data stored in SCRATCH3701 zone)

HOGENOM6: ISPAL1_2_PE1237

ID   ISPAL1_2_PE1237                      STANDARD;      PRT;   914 AA.
AC   ISPAL1_2_PE1237; E8R6D3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (ISPAL1_2.PE1237).
GN   OrderedLocusNames=Isop_1248;
OS   ISOSPHAERA PALLIDA ATCC 43644.
OC   Bacteria; Planctomycetes; Planctomycetacia; Planctomycetales;
OC   Planctomycetaceae; Isosphaera.
OX   NCBI_TaxID=575540;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ISPAL1_2.PE1237.
CC       Isosphaera pallida ATCC 43644 chromosome, complete genome.
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:E8R6D3_ISOPI
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E8R6D3; -.
DR   EMBL; CP002353; ADV61834.1; -; Genomic_DNA.
DR   RefSeq; YP_004178383.1; NC_014962.1.
DR   GeneID; 10155361; -.
DR   GenomeReviews; CP002353_GR; Isop_1248.
DR   KEGG; ipa:Isop_1248; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ISPAL1_2.PE1237; -.
DR   PRODOM; ISPAL1_2_PE1237.
DR   SWISS-2DPAGE; ISPAL1_2_PE1237.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   914 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSIAVATPPP SEPREPLPLN IEEELKESYL TYAMSVIVSR ALPDARDGLK PSQRRILAAM
     LDLGLTPGGS TSKCAGIVGE TMKRYHPHGD NSIYPTLARM AQWWNMRHLL VTGQGNFGSI
     HGLPPAAMRY TEAKLSPVAA EMLDDIKLDT VDFQPSYDEK HQEPRVLPAR FPNLLVNGSG
     GIAVGMATSI PPHNLGEVCD ALIALIDNPA IDFEDLIEKL PGPDFPTGGV ICGRMGIREA
     YLTGRGRIVL RAKHVVEETR DGRTQIVFTE IPYQLMKEPL LKKLGDLVNT DRIKGIADVV
     DESDRRQPVR IVVKLKRNED PNVILNQLYQ YSPLQDTFGV IMLALVDGRP KTLTLRELLK
     IYLDHRANVI RRRTAFLLRR DRARAHVVEG LLIALDMIDE IIHIIRSSPN PTEARTRLMG
     MAVGPDVMRR ALNDPEAQAT TGLTRNQADA ILAMRLQQLT GLELDKLVAE YRELRAAIAD
     AEDILAREVR VREIIKADLE ELKRKYADPR RTVISDEELG SYDKEALIRE EYMVVTITDG
     GYIKRLPPST YRAQGRGGRG KTAAGTKEGD FLAHMFVALT HDYLLFFTDQ GLIHWLKVYD
     VPIAPRTATG RAIVNLLELR EGERITGVIP VRRFPDNEFL FMATRRGTVK KTPLSAYSRP
     QRGGIIALGL EEGDQLIAVA RTQPGDHVIL STRNGMAIRF EESDVRPMGR PACGVRGIRL
     EGDDQVVGMV VANGPDDPAS LLTVCSNGFG KRTRLSEYRA QHRGGKGLID IKTTERNGPV
     VAIAKVTDAD EVMLTTERGI LIRTGLSETR DIGRNTQGVR LIRVDEGDRV VALAKLPESE
     LSQDQPDVAE VEPPPDSNAP PLAPSDRLLA NGILALDDLS GTDSASHEKE EEIPFDTGGD
     GLEPAEDDGV AADD
//

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