(data stored in SCRATCH3701 zone)

HOGENOM6: KINRD_2_PE2206

ID   KINRD_2_PE2206                       STANDARD;      PRT;   910 AA.
AC   KINRD_2_PE2206; A6W3W0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (KINRD_2.PE2206).
GN   OrderedLocusNames=Krad_0007;
OS   KINEOCOCCUS RADIOTOLERANS SRS30216.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Kineosporiineae; Kineosporiaceae; Kineococcus.
OX   NCBI_TaxID=266940;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS KINRD_2.PE2206.
CC       Kineococcus radiotolerans SRS30216, complete genome.
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:A6W3W0_KINRD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A6W3W0; -.
DR   EMBL; CP000750; ABS01499.1; -; Genomic_DNA.
DR   RefSeq; YP_001359763.1; NC_009664.2.
DR   ProteinModelPortal; A6W3W0; -.
DR   STRING; A6W3W0; -.
DR   GeneID; 5335382; -.
DR   GenomeReviews; CP000750_GR; Krad_0007.
DR   KEGG; kra:Krad_0007; -.
DR   NMPDR; fig|266940.1.peg.2654; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; KINRD_2.PE2206; -.
DR   PRODOM; KINRD_2_PE2206.
DR   SWISS-2DPAGE; KINRD_2_PE2206.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   910 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSESTTEPPH PGDRVEQVDL QAEMQRSYLD YAMSVIVSRA LPDVRDGLKP VHRRVLYAMY
     DGGYRPDRGY SKCARVVGDV MGHYHPHGDT SIYDALVRLA QDWSLRYPLV DGQGNFGSPG
     NDPAAAPRYT ECRMAPLAME MVRDIDEETV DFSPNYDGHT DEPDVLPSRF PNLLVNGSAG
     IAVGMATNIP PHNLREVAEG AKWLLDNPDA SDEEQLAALL TRIKGPDFPT GALILGHRGI
     SDAYRTGRGS ITMRAVVEVE EIQGRTCLVV SELPYQVNPD NLAENIANLV RDGRLTGIAD
     VQDHTSGKTG QRLVIILRRD AVAKVVLNNL YKHTQLQTNF GANMLALVDG VPRTLPIHAF
     LKHWIAHQLD VIVRRTRFRL RKAEERAHIL RALLKALDAL DEVIALIRAS PTVESARDGL
     MGLLEIDEIQ SRAILEMQLR RLAALERQRI TDEYDELMRM IGDFNDILAR PERQRQIVGD
     ELAELVERYG DERKTQILPF EGDMTVEDLI PVEDVVVTVT RGGYAKRTKT DLYRAQRRGG
     RGVRGASLRE DDVVEHFFTT TTHHWLLFFT NLGRVYRAKG YELPEGGRDG RGQHVANLLA
     FQPGERIVAV LDIEDYEQAP YLVLATRGGI VKKTRLSEYD SNRSGGLIAI NLRSHPGADG
     TEEVDDELFA ATLVSEDEDL FLVSRKGMSV RFEATDENLR PMGRATSGVT GMKFRGEDEL
     LAMAVARDDL FVFVVTELGY AKRTKIEHYR KQGRGGLGIK VAKLTEERGD LVGALTVSED
     DEVLVVMQAG RVVRSRVDEV PDKGRDTMGV TFARPETGDR ILAITRNVER VIDVEVEAEE
     VSEATTSGVD DPIADVAGSG DDLAAAEGAD EAPIGGAPVE ERGIDPVSGA GDGVPSPEAP
     TSEPDPGGDE
//

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