(data stored in ACNUC7421 zone)

HOGENOM: KLEP7_1_PE616

ID   KLEP7_1_PE616                        STANDARD;      PRT;   342 AA.
AC   KLEP7_1_PE616; A6T656;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase; (KLEP7_1.PE616).
GN   Name=mtnA; OrderedLocusNames=KPN78578_06160; ORFNames=KPN_00627;
OS   KLEBSIELLA PNEUMONIAE SUBSP. PNEUMONIAE MGH 78578.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=272620;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS KLEP7_1.PE616.
CC       Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:MTNA_KLEP7
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A6T656; -.
DR   EMBL; CP000647; ABR76077.1; -; Genomic_DNA.
DR   RefSeq; YP_001334307.1; NC_009648.1.
DR   ProteinModelPortal; A6T656; -.
DR   STRING; A6T656; -.
DR   GeneID; 5342223; -.
DR   GenomeReviews; CP000647_GR; KPN78578_06160.
DR   KEGG; kpn:KPN_00627; -.
DR   eggNOG; COG0182; -.
DR   OMA; RPRNQGA; -.
DR   ProtClustDB; CLSK928047; -.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_01678; Salvage_MtnA; 1; -.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; KLEP7_1.PE616; -.
KW   methyltransferase domain-containing protein;
KW   Amino-acid biosynthesis; Complete proteome; Isomerase;
KW   Methionine biosynthesis.
SQ   SEQUENCE   342 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQTLQTTSLR VSENQLFILD QQALPQETRW LAADNVALLV DHIHTLRVRG APLIGLSASL
     LLALLAQRGL NRDALQQALE TLRAARPTAV NLMNNLDRMK QALAREDYPQ ALEAEALRLV
     EEDKQLCARI AEAGSALVKP GSRLLTHCNT GGLATAGVGT ALGVIALAHR QGKVTNVWVD
     ETRPLLQGGR LTAWELGELG VPYQLIADSM AASLMAQGQV DAVWVGADRI AANGDVANKI
     GTYSLAVLAH YHQIPFYVAA PQTTLDRYCP NGAAIPIEQR AAAEVTGVAG SFGAVQWAPT
     GAAVYNPAFD VTPAGLISGW VLDSGVVTPA QVAAGAFAPD NG
//

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