(data stored in ACNUC14238 zone)

HOGENOM: KLLAC1_1_PE5

ID   KLLAC1_1_PE5                         STANDARD;      PRT;   534 AA.
AC   KLLAC1_1_PE5; P20386; Q6DN59;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Cytochrome c oxidase subunit 1; EC=1.9.3 1;AltName:
DE   Full=Cytochrome c oxidase polypeptide I; (KLLAC1_1.PE5).
GN   Name=COX1;
OS   KLUYVEROMYCES LACTIS NRRL Y-1140.
OG   Mitochondrion.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS KLLAC1_1.PE5.
CC       Kluyveromyces lactis (strain CBS 2359 / WM37 / ATCC 8585 / DSM 70799 /
CC       NRRL Y-1140) mitochondrion, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:COX1_KLULA
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B.
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass
CC       membrane protein.
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC   -!- GENE_FAMILY: HOG000085274 [ FAMILY / ALN / TREE ]
DR   EMBL; CAA34130.1; - ;
DR   EMBL; CAA40765.1; - ;
DR   UniProtKB/Swiss-Prot; P20386; Q6DN59; -.
DR   EMBL; X57546; CAA40765.1; -; Genomic_DNA.
DR   EMBL; AY654900; AAT64956.1; -; Genomic_DNA.
DR   EMBL; X15999; CAA34130.1; -; Genomic_DNA.
DR   PIR; S17993; S17993.
DR   RefSeq; YP_054500.1; NC_006077.1.
DR   ProteinModelPortal; P20386; -.
DR   SMR; P20386; 2-532.
DR   STRING; P20386; -.
DR   GeneID; 2914076; -.
DR   GenomeReviews; AY654900_GR; COX1.
DR   KEGG; kla:KllafMp05; -.
DR   OrthoDB; EOG4BK8C4; -.
DR   PhylomeDB; P20386; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
DR   InterPro; IPR000883; Cyt_c_Oxase_su1.
DR   InterPro; IPR023615; Cyt_c_Oxase_su1_BS.
DR   InterPro; IPR023616; Cyt_c_Oxase_su1_dom.
DR   Gene3D; G3DSA:1.20.210.10; COX1; 1.
DR   PANTHER; PTHR10422; COX1; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; COX1; 1.
DR   PROSITE; PS50855; COX1; 1.
DR   PROSITE; PS00077; COX1_CUB; 1.
DR   HOGENOMDNA; KLLAC1_1.PE5; -.
KW   AAT64956.1824841755old_1320000031; CAA34130.1; CAA40765.1;
KW   Cytochrome c oxidase subunit 1 ;
KW   Complete proteome; Copper; Electron transport; Heme; Iron; Membrane;
KW   Metal-binding; Mitochondrion; Mitochondrion inner membrane;
KW   Oxidoreductase; Respiratory chain; Transmembrane; Transmembrane helix;
KW   Transport.
SQ   SEQUENCE   534 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MIERWLYSTN AKDIAVLYFI FAIFCGMAGT AMSLIIRLEL AAPGNQVLSG NHQLFNVLVV
     GHAVLIIFFL VMPALIGGFG NYMLPLLIGA SDMSFARLNN ISFWCLPPAL VCLVTSTLVE
     SGAGTGWTVY PPLSSIQAHS GPSVDLAIFA LHLTSISSLL GAINFIVTTL NMRTNGMTMH
     RLPLFVWSIF ITAFLLLLSL PVLSAGVTML LLDRNFNTSF FEVAGGGDPV LYQHLFWFFG
     HPEVYILIIP GFGIISHIVS TYSKKPVFGE VSMVYAMASI GLLGFLVWSH HMYIVGLDAD
     TRAYFTSATM IIAIPTGIKI FSWLATIYGG SIRLAVPMLY AIAFLFLFTI GGLTGVALAN
     ASLDVAFHDT YYVVGHFHYV LSMGAIFSLF AGYYYWSPQI LGLYYNEKLA QIQFWLIFVG
     ANVIFLPMHF LGVNGMPRRI PDYPDAFAGW NYVASIGSII AVFSLFLFIY ILYDQLVNGL
     ENKVNNKSVI YNKGPDFVES NQIFATNKIK SSSIEFLLTS PPAVHTFNTP AVQS
//

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