(data stored in ACNUC14238 zone)

HOGENOM: KLLAC1_1_PE7

ID   KLLAC1_1_PE7                         STANDARD;      PRT;   256 AA.
AC   KLLAC1_1_PE7; P20387; Q6DN57;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Cytochrome c oxidase subunit 2; EC=1.9.3 1;AltName:
DE   Full=Cytochrome c oxidase polypeptide II;Flags: Precursor;
DE   (KLLAC1_1.PE7).
GN   Name=COX2;
OS   KLUYVEROMYCES LACTIS NRRL Y-1140.
OG   Mitochondrion.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS KLLAC1_1.PE7.
CC       Kluyveromyces lactis (strain CBS 2359 / WM37 / ATCC 8585 / DSM 70799 /
CC       NRRL Y-1140) mitochondrion, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:COX2_KLULA
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. Subunit 2
CC       transfers the electrons from cytochrome c via its binuclear copper
CC       A center to the bimetallic center of the catalytic subunit 1.
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O.
CC   -!- COFACTOR: Copper A.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass
CC       membrane protein.
CC   -!- PTM: The signal sequence of COX2 is processed by IMP1.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 2 family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAT64953.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000264988 [ FAMILY / ALN / TREE ]
DR   EMBL; CAA34129.2; - ;
DR   UniProtKB/Swiss-Prot; P20387; Q6DN57; -.
DR   EMBL; X15999; CAA34129.2; -; Genomic_DNA.
DR   EMBL; AY654900; AAT64953.1; ALT_INIT; Genomic_DNA.
DR   PIR; S11171; OBVK2M.
DR   ProteinModelPortal; P20387; -.
DR   STRING; P20387; -.
DR   GenomeReviews; AY654900_GR; COX2.
DR   KEGG; kla:KllafMp06; -.
DR   OrthoDB; EOG4ZW8M5; -.
DR   PhylomeDB; P20387; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro.
DR   InterPro; IPR001505; Copper_CuA.
DR   InterPro; IPR008972; Cupredoxin.
DR   InterPro; IPR014222; Cyt_c_oxidase_su2.
DR   InterPro; IPR015964; Cyt_c_oxidase_su2-like_TM_dom.
DR   InterPro; IPR002429; Cyt_c_oxidase_su2_C.
DR   InterPro; IPR011759; Cyt_c_oxidase_su2_TM_dom.
DR   Gene3D; G3DSA:1.10.287.90; COX2_TM; 1.
DR   Gene3D; G3DSA:2.60.40.420; Cupredoxin; 1.
DR   Pfam; PF00116; COX2; 1.
DR   Pfam; PF02790; COX2_TM; 1.
DR   PRINTS; PR01166; CYCOXIDASEII.
DR   SUPFAM; SSF49503; Cupredoxin; 1.
DR   SUPFAM; SSF81464; Cyt_c_oxidase_II-like_TM; 1.
DR   TIGRFAMs; TIGR02866; CoxB; 1.
DR   PROSITE; PS00078; COX2; 1.
DR   PROSITE; PS50857; COX2_CUA; 1.
DR   PROSITE; PS50999; COX2_TM; 1.
DR   HOGENOMDNA; KLLAC1_1.PE7; -.
KW   AAT64953.1824841755old_1320000031; CAA34129.2;
KW   Cytochrome c oxidase subunit 2 ;
KW   Complete proteome; Copper; Electron transport; Membrane;
KW   Metal-binding; Mitochondrion; Mitochondrion inner membrane;
KW   Oxidoreductase; Respiratory chain; Signal; Transmembrane;
KW   Transmembrane helix; Transport.
SQ   SEQUENCE   256 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MYRLKKIINM FYLLNSIIMN DVPTPYGMYF QDSATPNQEG ILELHDNIMF YLFIILGLVS
     WLLFTIVRTY SKNPIAYKYI KHGQTIEIIW TIFPAVILLI IAFPSFILLY LCDEVISPAM
     TIKAIGLQWY WKYEYSDFIN DNGETVEFES YVIPEDLLED GQLRLLDTDT SVVVPVDTHI
     RFVVTAADVI HDFAVPSLGI KIDAAPGRLN QVSALIQREG VFYGQCSEIC GQSHSAMPIK
     IEAVSLPAFL EWLNEQ
//

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