(data stored in ACNUC7421 zone)

HOGENOM: LACAR_1_PE1

ID   LACAR_1_PE1                          STANDARD;      PRT;   455 AA.
AC   LACAR_1_PE1; E4SJ56;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (LACAR_1.PE1).
GN   Name=dnaA; OrderedLocusNames=LA2_00005;
OS   LACTOBACILLUS AMYLOVORUS GRL 1112.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=695560;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACAR_1.PE1.
CC       Lactobacillus amylovorus GRL 1112 chromosome, complete genome.
CC       NRRL Y-1140) chromosome F, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E4SJ56_LACAR
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- SIMILARITY: Belongs to the dnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E4SJ56; -.
DR   EMBL; CP002338; ADQ58004.1; -; Genomic_DNA.
DR   RefSeq; YP_004030799.1; NC_014724.1.
DR   GeneID; 10024112; -.
DR   GenomeReviews; CP002338_GR; LA2_00005.
DR   KEGG; lam:LA2_00005; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:HAMAP.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:HAMAP.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; LACAR_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   455 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MFDIEKFWQH FNDEMRARFN EVAYNAWFKN TKPISYDKKT HELQILVQNP VAKGYWEKNL
     SSQLIQSAYG YAGIEILPVF KISEDSDTPE RIVTPEPQHD IRVQPRNREQ QEFTKDLKLN
     EKYTFDNFVQ GEGNKLAAGA ALAVADSPGS FYNPLFIFGG VGLGKTHLMQ AIGHQMLLER
     PNAKVVYIQS ETFVNDFINS IKNKTQDQFR EKYRTCDLLL VDDIQFFAKK EGIQEEFFHT
     FETLYNDQKQ IVMTSDRLPT EIPDLSERLV SRFTWGLQVE ITPPDLETRI AILRRKAESE
     GLTIDDNTLD YIASQVDTNI RELEGALVKV QAYATIEKAD IDVNLAREAL VDLKLVQKNR
     GLQISKIQEV VANYFQTSTA ELKGKKRVRQ IVVPRQIAMY LSRELTDASL PKIGQEFGGK
     DHTTVMHAYD KIDKQMKTDA DIKTAVFDLK QMLEH
//

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