(data stored in SCRATCH3701 zone)

HOGENOM6: LACAR_1_PE6

ID   LACAR_1_PE6                          STANDARD;      PRT;   821 AA.
AC   LACAR_1_PE6; E4SJ61;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; (LACAR_1.PE6).
GN   OrderedLocusNames=LA2_00030;
OS   LACTOBACILLUS AMYLOVORUS GRL 1112.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=695560;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACAR_1.PE6.
CC       Lactobacillus amylovorus GRL 1112 chromosome, complete genome.
CC       NRRL Y-1140) chromosome F, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E4SJ61_LACAR
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E4SJ61; -.
DR   EMBL; CP002338; ADQ58009.1; -; Genomic_DNA.
DR   RefSeq; YP_004030804.1; NC_014724.1.
DR   GeneID; 10021991; -.
DR   GenomeReviews; CP002338_GR; LA2_00030.
DR   KEGG; lam:LA2_00030; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LACAR_1.PE6; -.
DR   PRODOM; LACAR_1_PE6.
DR   SWISS-2DPAGE; LACAR_1_PE6.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   821 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDENQTQDHR IRNVDLTSMM RSSFLDYAMS VIVARALPDV RDGLKPVQRR ILYGMSELGV
     TPDKPYKKSA RIVGEVMGKF HPHGDSSIYL AMAHMAQDFS YRYMLVDGHG NFGSVDGDEP
     AAMRYTEARM SKIAVEMLRD INKNTIDWQR NYDDTENEPV VLPARIPNLL VNGANGIAVG
     MTTNIPPHNL SEVISGLHML MKNPDATTKD LMKVIPGPDF PTGGIIMGRG GIYRAYETGK
     GNIVVRAKTN IETEKSGRER IIVSEIPFMV NKAELVKKIA DLAREKIIDG ITGVRDESDQ
     TGMRITIDIR RDASASVVLN NLFKQTQMQA NFGMNMVAIV DGAPHYLTLK QMLQYYLDHQ
     EDVVTRRTKF ELAKAEARAH ILEGLRIALD NIDEIVHIIR SSHSSDIAKA TLISRFGLDD
     KQSQAILDMR LVRLTGLERD KVEAEYKDLQ AKIADYKDIL AKPERIDQII YDELLDIQKR
     FGDKRRTEIG ASEVVSIEDE DLIEKQNILL TVTHNGYIKR MPIQEFKTQN RGGKGIKGMG
     VQDGDFIEHL IYSSTHDMLL FFTNAGKVYS KKAYEIPEYG RMAKGLPVVN LLQLEKGEKV
     QTVINIPENA DDNYLFFITK MGTVKRTHVS EFSNIRNSGL IALTLRDGDE LSNVLTTDGN
     QNILIGTHLG YAVTFKESDV RAMGRTAAGV RGINLRENDY VVGSGVLGKD DQVLVISEKG
     YGKRTPAAEY PVKGRGGKGI KTANITEKNG PLAGVIVVDK GKDIMVITTN GIMIRFKTKD
     VSQTGRSTMG VRLIKVNDDS KVASLTIVPT EAEQNQTDDD E
//

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