(data stored in SCRATCH3701 zone)

HOGENOM6: LACBA_1_PE6

ID   LACBA_1_PE6                          STANDARD;      PRT;   844 AA.
AC   LACBA_1_PE6; Q03UD9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (LACBA_1.PE6).
GN   OrderedLocusNames=LVIS_0006;
OS   LACTOBACILLUS BREVIS ATCC 367.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=387344;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACBA_1.PE6.
CC       Lactobacillus brevis ATCC 367, complete genome.
CC       NRRL Y-1140) chromosome F, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q03UD9_LACBA
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q03UD9; -.
DR   EMBL; CP000416; ABJ63183.1; -; Genomic_DNA.
DR   RefSeq; YP_794214.1; NC_008497.1.
DR   ProteinModelPortal; Q03UD9; -.
DR   SMR; Q03UD9; 32-488.
DR   STRING; Q03UD9; -.
DR   GeneID; 4414203; -.
DR   GenomeReviews; CP000416_GR; LVIS_0006.
DR   KEGG; lbr:LVIS_0006; -.
DR   NMPDR; fig|387344.8.peg.7; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q03UD9; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LACBA_1.PE6; -.
DR   PRODOM; LACBA_1_PE6.
DR   SWISS-2DPAGE; LACBA_1_PE6.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   844 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MADQDYLGRV TDVDLSQTMR TSFLDYAMSV IVQRALPDVR DGLKPVHRRI LYDMHELGIT
     PDKPFRKSAR MVGDVLGKYH PHGDSAVYES MVRMAQDFSY RYMLVDGHGN FGSVDGDGAA
     AMRYTEARLS KIAMEMLRDI NKDTIDFQDN YDGSEREPVV LPSRFPNLLV NGASGIAVGM
     ATNIPPHNLT EVISALHILM KNPDASLADL MEALPGPDFP TGGIVMGKAA IRRAYETGKG
     TITLRAKVDI EEEKNGKQRI VATEIPYMVN KAKLIERIAE LARDKRIEGI TDVNDETDRT
     GMRIVIDVRR DASAEVILNN LYKMTLMQTS FGINMLAIVN GAPKVLGLKA ILQYYLEFQL
     EVIRRRTEFD LRKAEARAHI LEGLRIALDH IDEIITIIRQ SQTADVAKQE LITRFSLSDK
     QSQAILDMRL VRLTGLEREK VEKEYADVMA NIKDYKEILA SKERQQAIIY EELLEIQNKF
     GDDRRTELMV GEVLSLEDED LIAEEDVVVS LTHNGYIKRL PTSEFKAQNR GGKGVQGMGV
     HDDDFIEHLV ATSTHDMLLF FTNTGKVYRM KGYEIPEYGR TAKGIPVINL LGINNNEHVQ
     AVINVANPGE NDNRDLFFTT VQGTVKRTPV DEFANIRSNG LKAINLKEDD ELIDVDIINA
     DANMIIGTHL GYAVSFAATD VRSMGRSATG VRGIRLREHD YVIGASVLKP DSKVFVISEK
     GYGKQTAAAE YPIKGRGGKG IKTVNVSTKN GPLAGLTTLD GDEDIMLVTN KGVMIRFSAS
     DVSETGRATL GVHLIRLADD TAVATMAKVA KEDETADEAP VVDGETPATT DGPVVPESDD
     PTEA
//

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