(data stored in SCRATCH3701 zone)

HOGENOM6: LACC3_2_PE6

ID   LACC3_2_PE6                          STANDARD;      PRT;   873 AA.
AC   LACC3_2_PE6; Q03D50;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (LACC3_2.PE6).
GN   OrderedLocusNames=LSEI_0006;
OS   LACTOBACILLUS CASEI ATCC 334.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=321967;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACC3_2.PE6.
CC       Lactobacillus casei ATCC 334, complete genome.
CC       NRRL Y-1140) chromosome F, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q03D50_LACC3
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q03D50; -.
DR   EMBL; CP000423; ABJ68872.1; -; Genomic_DNA.
DR   RefSeq; YP_805314.1; NC_008526.1.
DR   ProteinModelPortal; Q03D50; -.
DR   SMR; Q03D50; 31-487.
DR   STRING; Q03D50; -.
DR   GeneID; 4419513; -.
DR   GenomeReviews; CP000423_GR; LSEI_0006.
DR   KEGG; lca:LSEI_0006; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q03D50; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LACC3_2.PE6; -.
DR   PRODOM; LACC3_2_PE6.
DR   SWISS-2DPAGE; LACC3_2_PE6.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   873 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDDRQESRIT NVNLGETMRK SFLEYAMSVI VARALPDVRD GLKPVQRRIL YGMNELGVTP
     DKPYKKSARI VGDVMGKYHP HGDSSIYEGL VRMAQDFSYR YMLVDGHGNF GSVDGDGAAA
     MRYTEARMSK IAVEMLRDIN KDTIDFQDNY DGTEKEPVVL PARFPNLLVN GATGIAVGMT
     TNIPPHNLSE TISALHVLMD NPDATTADLM QALPGPDFPT GGVVMGKSGI RHAYETGRGT
     IVLRGKVDVQ TEKSGRERIV ITEIPYMVNK AKMVERIADL VHEKKIDGIV TLRDESDRDG
     MRIVIDVRRD ASASVILNNL YKLTPLQTGF SFNMVAIVNG APKVLSLKQI LQYYLDHQEN
     VIRRRTQFDL RKANAREHIL EGLRIALDHI DEIITIIRSS ETGDKAKVIL MDKFKLSDKQ
     SQAILDMRLV RLTGLEREKV ESEYKDVEAA IADYTDILAR PERVHQIIYN ELLDIQKKFG
     DKRRTELLVG EVLSLEDEDL IEQEDVVITL SHNGYVKRLA TSEFKAQNRG GRGIQGMNVH
     DDDFVERLIS TSTHDVLLFF TNKGKVYRSK GYEIPEYGRT AKGIPIINLL GVGAGEKIQT
     VINVHEGEND DRYLFFVTQK GVVKRTPVKE FANIRSNGLI ALNLKDEDEL NNVILTSGQD
     NILIGTHLGY SVTFKEQDVR SMGRSATGVR GIRLREHDYV VGSDILKPDS EVFVISEKGY
     GKRTAAKEYP IKGRGGKGIK TANITAKNGP LAGVTTVDGT EDILVMTDSG VMIRFNIQSV
     SQTGRATLGV RLIRVDDDAK VATMAKVEPE SDDPDDGSKP DQPTSPTDGS AAPTSQQPAD
     GSYAGDADQQ VSQLLDRAEA DQPEQHDTGD QPE
//

If you have problems or comments...

PBIL Back to PBIL home page