(data stored in ACNUC7421 zone)

HOGENOM: LACCS_1_PE1000

ID   LACCS_1_PE1000                       STANDARD;      PRT;   312 AA.
AC   LACCS_1_PE1000; D5H362;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ribonuclease Z; Short=RNase Z; EC=3.1.26 11;AltName:
DE   Full=tRNA 3 endonuclease;AltName: Full=tRNase Z; (LACCS_1.PE1000).
GN   Name=elaC; Synonyms=rnz; OrderedLocusNames=LCRIS_01000;
OS   LACTOBACILLUS CRISPATUS ST1.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=748671;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACCS_1.PE1000.
CC       Lactobacillus crispatus ST1, complete genome.
CC       NRRL Y-1140) chromosome F, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:D5H362_LACCS
CC   -!- FUNCTION: Zinc phosphodiesterase, which displays some tRNA 3'-
CC       processing endonuclease activity. Probably involved in tRNA
CC       maturation, by removing a 3'-trailer from precursor tRNA (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: Endonucleolytic cleavage of RNA, removing
CC       extra 3' nucleotides from tRNA precursor, generating 3' termini of
CC       tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-
CC       phosphoryl group is left at the trailer molecule.
CC   -!- COFACTOR: Binds 2 zinc ions (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the RNase Z family.
CC   -!- GENE_FAMILY: HOG000272419 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D5H362; -.
DR   EMBL; FN692037; CBL50447.1; -; Genomic_DNA.
DR   RefSeq; YP_003601472.1; NC_014106.1.
DR   ProteinModelPortal; D5H362; -.
DR   GeneID; 9106342; -.
DR   GenomeReviews; FN692037_GR; LCRIS_01000.
DR   KEGG; lcr:LCRIS_01000; -.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042779; P:tRNA 3'-trailer cleavage; IEA:InterPro.
DR   HAMAP; MF_01818; RNase_Z; 1; -.
DR   InterPro; IPR001279; Beta-lactamas-like.
DR   InterPro; IPR013471; RNase_Z.
DR   SMART; SM00849; Lactamase_B; 1.
DR   TIGRFAMs; TIGR02651; RNase_Z; 1.
DR   HOGENOMDNA; LACCS_1.PE1000; -.
KW   ribonuclease z;
KW   Complete proteome; Endonuclease; Hydrolase; Metal-binding; Nuclease;
KW   tRNA processing; Zinc.
SQ   SEQUENCE   312 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MELQFLGTGA GQPSKQRNVS SVALKLLDEL NEIWLFDVGE ATQHQILRTN IKLRKVTKIF
     ISHNHGDHIF GLPGLLSTRS FQGDVGPITI YGPSGIEEFV RTALKVSRTK ISYPIRFVEL
     AKSGLICEDK GFRVYTEQLD HRIPSFGFRV VEASHPGELL IDKLAQYNVP NGPLLGKLKN
     GEKVTLADGT VLDGKNFLGP TKSGRIVTVI YDTRSTPSIA RLAKDADVLV HESTFAGDEQ
     KLAHDYYHST SVEAAKIARK DNVKLLCLNH ISARYMGAKA KKLEKQAKKV FSNTVLVNDF
     DQINIPMKGS EK
//

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